Angewandte Chemie - International Edition, volume 55, issue 44, pages 13658-13699
Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes
1
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering; Hunan University; Changsha 410082 P.R. China
|
3
Laboratory of Bioimaging Probe Development, A*STAR; Singapore
|
4
Department of Chemistry; Stanford University; USA
|
Publication type: Journal Article
Publication date: 2016-08-29
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 16.6
ISSN: 14337851, 15213773
General Chemistry
Catalysis
Abstract
Principle has it that even the most advanced super-resolution microscope would be futile in providing biological insight into subcellular matrices without well-designed fluorescent tags/probes. Developments in biology have increasingly been boosted by advances of chemistry, with one prominent example being small-molecule fluorescent probes that not only allow cellular-level imaging, but also subcellular imaging. A majority, if not all, of the chemical/biological events take place inside cellular organelles, and researchers have been shifting their attention towards these substructures with the help of fluorescence techniques. This Review summarizes the existing fluorescent probes that target chemical/biological events within a single organelle. More importantly, organelle-anchoring strategies are described and emphasized to inspire the design of new generations of fluorescent probes, before concluding with future prospects on the possible further development of chemical biology.
Citations by journals
|
5
10
15
20
25
30
35
40
45
|
|
|
Analytical Chemistry
|
Analytical Chemistry
44 publications, 7.01%
|
|
Sensors and Actuators, B: Chemical
|
Sensors and Actuators, B: Chemical
40 publications, 6.37%
|
|
Dyes and Pigments
|
Dyes and Pigments
32 publications, 5.1%
|
|
Chemical Communications
|
Chemical Communications
29 publications, 4.62%
|
|
Chemical Science
|
Chemical Science
28 publications, 4.46%
|
|
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
|
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
22 publications, 3.5%
|
|
Journal of Materials Chemistry B
|
Journal of Materials Chemistry B
22 publications, 3.5%
|
|
Chinese Chemical Letters
|
Chinese Chemical Letters
18 publications, 2.87%
|
|
New Journal of Chemistry
|
New Journal of Chemistry
15 publications, 2.39%
|
|
Analytica Chimica Acta
|
Analytica Chimica Acta
14 publications, 2.23%
|
|
Journal of the American Chemical Society
|
Journal of the American Chemical Society
13 publications, 2.07%
|
|
The Analyst
|
The Analyst
13 publications, 2.07%
|
|
Angewandte Chemie
|
Angewandte Chemie
12 publications, 1.91%
|
|
Angewandte Chemie - International Edition
|
Angewandte Chemie - International Edition
12 publications, 1.91%
|
|
Chemistry - A European Journal
|
Chemistry - A European Journal
11 publications, 1.75%
|
|
Organic and Biomolecular Chemistry
|
Organic and Biomolecular Chemistry
11 publications, 1.75%
|
|
Coordination Chemistry Reviews
|
Coordination Chemistry Reviews
9 publications, 1.43%
|
|
ACS Sensors
|
ACS Sensors
9 publications, 1.43%
|
|
ACS applied materials & interfaces
|
ACS applied materials & interfaces
9 publications, 1.43%
|
|
Talanta
|
Talanta
8 publications, 1.27%
|
|
Chemistry - An Asian Journal
|
Chemistry - An Asian Journal
8 publications, 1.27%
|
|
Frontiers in Chemistry
|
Frontiers in Chemistry
6 publications, 0.96%
|
|
ACS Applied Bio Materials
|
ACS Applied Bio Materials
6 publications, 0.96%
|
|
RSC Advances
|
RSC Advances
6 publications, 0.96%
|
|
Tetrahedron
|
Tetrahedron
5 publications, 0.8%
|
|
ChemistrySelect
|
ChemistrySelect
5 publications, 0.8%
|
|
ChemBioChem
|
ChemBioChem
5 publications, 0.8%
|
|
Analytical and Bioanalytical Chemistry
|
Analytical and Bioanalytical Chemistry
4 publications, 0.64%
|
|
Science China Chemistry
|
Science China Chemistry
4 publications, 0.64%
|
|
5
10
15
20
25
30
35
40
45
|
Citations by publishers
|
50
100
150
200
250
|
|
|
Elsevier
|
Elsevier
208 publications, 33.12%
|
|
Royal Society of Chemistry (RSC)
|
Royal Society of Chemistry (RSC)
148 publications, 23.57%
|
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
116 publications, 18.47%
|
|
Wiley
|
Wiley
85 publications, 13.54%
|
|
Springer Nature
|
Springer Nature
24 publications, 3.82%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
11 publications, 1.75%
|
|
Frontiers Media S.A.
|
Frontiers Media S.A.
7 publications, 1.11%
|
|
IOP Publishing
|
IOP Publishing
4 publications, 0.64%
|
|
Taylor & Francis
|
Taylor & Francis
2 publications, 0.32%
|
|
Walter de Gruyter
|
Walter de Gruyter
2 publications, 0.32%
|
|
Beilstein-Institut
|
Beilstein-Institut
1 publication, 0.16%
|
|
The Chemical Society of Japan
|
The Chemical Society of Japan
1 publication, 0.16%
|
|
International Union of Crystallography (IUCr)
|
International Union of Crystallography (IUCr)
1 publication, 0.16%
|
|
Society of Synthetic Organic Chemistry
|
Society of Synthetic Organic Chemistry
1 publication, 0.16%
|
|
Japan Society for Analytical Chemistry
|
Japan Society for Analytical Chemistry
1 publication, 0.16%
|
|
King Saud University
|
King Saud University
1 publication, 0.16%
|
|
Scientific Publishers
|
Scientific Publishers, 1, 0.16%
Scientific Publishers
1 publication, 0.16%
|
|
American Association for the Advancement of Science (AAAS)
|
American Association for the Advancement of Science (AAAS)
1 publication, 0.16%
|
|
Pleiades Publishing
|
Pleiades Publishing
1 publication, 0.16%
|
|
Proceedings of the National Academy of Sciences (PNAS)
|
Proceedings of the National Academy of Sciences (PNAS)
1 publication, 0.16%
|
|
50
100
150
200
250
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2016,2017,2018,2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0,0,0],"imageUrls":["","","","","","","","",""],"datasets":[{"label":"Citations number","data":[6,68,89,93,85,92,93,81,21],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["0.96","10.83","14.17","14.81","13.54","14.65","14.81","12.9","3.34"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Analytical Chemistry","Sensors and Actuators, B: Chemical","Dyes and Pigments","Chemical Communications","Chemical Science","Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy","Journal of Materials Chemistry B","Chinese Chemical Letters","New Journal of Chemistry","Analytica Chimica Acta","Journal of the American Chemical Society","The Analyst","Angewandte Chemie","Angewandte Chemie - International Edition","Chemistry - A European Journal","Organic and Biomolecular Chemistry","Coordination Chemistry Reviews","ACS Sensors","ACS applied materials & interfaces","Talanta","Chemistry - An Asian Journal","Frontiers in Chemistry","ACS Applied Bio Materials","RSC Advances","Tetrahedron","ChemistrySelect","ChemBioChem","Analytical and Bioanalytical Chemistry","Science China Chemistry"],"ids":[18157,22419,10101,9073,9646,6337,11516,20341,1404,19094,4813,9343,25450,19215,24708,541,13437,8271,1458,4331,10120,6407,21728,3100,3439,8021,12154,10563,14409],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp"],"datasets":[{"label":"","data":[44,40,32,29,28,22,22,18,15,14,13,13,12,12,11,11,9,9,9,8,8,6,6,6,5,5,5,4,4],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[7.01,6.37,5.1,4.62,4.46,3.5,3.5,2.87,2.39,2.23,2.07,2.07,1.91,1.91,1.75,1.75,1.43,1.43,1.43,1.27,1.27,0.96,0.96,0.96,0.8,0.8,0.8,0.64,0.64],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Royal Society of Chemistry (RSC)","American Chemical Society (ACS)","Wiley","Springer Nature","Multidisciplinary Digital Publishing Institute (MDPI)","Frontiers Media S.A.","IOP Publishing","Taylor & Francis","Walter de Gruyter","Beilstein-Institut","The Chemical Society of Japan","International Union of Crystallography (IUCr)","Society of Synthetic Organic Chemistry","Japan Society for Analytical Chemistry","King Saud University","Scientific Publishers","American Association for the Advancement of Science (AAAS)","Pleiades Publishing","Proceedings of the National Academy of Sciences (PNAS)"],"ids":[17,123,40,11,8,202,208,2075,18,4,6139,6950,730,1303,1070,171,562,189,101,162],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/3SpVxcYL33bOvPq4sHxJLH2NeKNeDloahSUpNiO4_medium.webp","\/storage\/images\/resized\/ex6KJoZujZOZFZh7jGfeHauiftuB3CI7iwJVFRDg_medium.webp","\/storage\/images\/resized\/ktSZPrGjOMvauY6mn7jk8bqo3Af0S6abv653w90B_medium.webp","\/storage\/images\/resized\/xG3oC19920mmFVqkoVEGKGaMCeoalzyvWxPkVox5_medium.webp","\/storage\/images\/resized\/QzzkQMUwda0fYU3txrAv3z24JfXJEjptEQpWMERc_medium.webp","\/storage\/images\/resized\/MriDiasGda8aAymM983PIz18dzVMXwO888XReHom_medium.webp","\/storage\/images\/resized\/9z7b0TQJNgUxZHYXLrTmbnjJn9y5iq56Wxtqb1Lv_medium.webp","","\/storage\/images\/resized\/s10mcsCV4OAUg9O2KrqOquQC0PhyLMI8hUUkuflM_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/mxFdPe9qujsfvfYfcN0QOclAiYORFb0xrRlwV8gs_medium.webp"],"datasets":[{"label":"","data":[208,148,116,85,24,11,7,4,2,2,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[33.12,23.57,18.47,13.54,3.82,1.75,1.11,0.64,0.32,0.32,0.16,0.16,0.16,0.16,0.16,0.16,0.16,0.16,0.16,0.16],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Wang X. et al. Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes // Angewandte Chemie - International Edition. 2016. Vol. 55. No. 44. pp. 13658-13699.
GOST all authors (up to 50)
Copy
Wang X., Zeng Z., Jiang J., Chang Y., Yuan L. Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes // Angewandte Chemie - International Edition. 2016. Vol. 55. No. 44. pp. 13658-13699.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/anie.201510721
UR - https://doi.org/10.1002%2Fanie.201510721
TI - Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes
T2 - Angewandte Chemie - International Edition
AU - Wang, Xu
AU - Yuan, Lin
AU - Zeng, Zebing
AU - Jiang, Jianhui
AU - Chang, Young-Tae
PY - 2016
DA - 2016/08/29 00:00:00
PB - Wiley
SP - 13658-13699
IS - 44
VL - 55
SN - 1433-7851
SN - 1521-3773
ER -
Cite this
BibTex
Copy
@article{2016_Wang,
author = {Xu Wang and Lin Yuan and Zebing Zeng and Jianhui Jiang and Young-Tae Chang},
title = {Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes},
journal = {Angewandte Chemie - International Edition},
year = {2016},
volume = {55},
publisher = {Wiley},
month = {aug},
url = {https://doi.org/10.1002%2Fanie.201510721},
number = {44},
pages = {13658--13699},
doi = {10.1002/anie.201510721}
}
Cite this
MLA
Copy
Wang, Xu, et al. “Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes.” Angewandte Chemie - International Edition, vol. 55, no. 44, Aug. 2016, pp. 13658-13699. https://doi.org/10.1002%2Fanie.201510721.