Journal of Biochemical and Molecular Toxicology, volume 32, issue 12, pages e22225
Toxicity of iron oxide nanoparticles: Size and coating effects
Abakumov Maxim A.
1, 2
,
Semkina Alevtina S.
1
,
Skorikov Alexander S.
3
,
Vishnevskiy Daniil A
1
,
Ivanova Anna V.
2
,
Mironova Elena
4
,
Majouga Alexander G.
2, 5
,
Чехонин В. П.
1
Publication type: Journal Article
Publication date: 2018-10-05
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor: 3.6
ISSN: 10956670, 10990461
Biochemistry
Molecular Biology
General Medicine
Molecular Medicine
Health, Toxicology and Mutagenesis
Toxicology
Abstract
Toxicological research of novel nanomaterials is a major developmental step of their clinical approval. Since iron oxide magnetic nanoparticles have a great potential in cancer treatment and diagnostics, the investigation of their toxic properties is very topical. In this paper we synthesized bovine serum albumin‐coated iron oxide nanoparticles with different sizes and their polyethylene glycol derivative. To prove high biocompatibility of obtained nanoparticles the number of in vitro toxicological tests on human fibroblasts and U251 glioblastoma cells was performed. It was shown that albumin nanoparticles’ coating provides a stable and biocompatible shell and prevents cytotoxicity of magnetite core. On long exposure times (48 hours), cytotoxicity of iron oxide nanoparticles takes place due to free radical production, but this toxic effect may be neutralized by using polyethylene glycol modification.
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1
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1 publication, 1.27%
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1 publication, 1.27%
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1
2
3
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Citations by publishers
2
4
6
8
10
12
14
16
18
20
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Elsevier
|
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19 publications, 24.05%
|
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12 publications, 15.19%
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Wiley
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4 publications, 5.06%
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4 publications, 5.06%
|
Taylor & Francis
|
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3 publications, 3.8%
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2 publications, 2.53%
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|
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2 publications, 2.53%
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2 publications, 2.53%
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1 publication, 1.27%
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1 publication, 1.27%
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Hindawi Limited
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World Scientific
|
World Scientific
1 publication, 1.27%
|
American Institute of Physics (AIP)
|
American Institute of Physics (AIP)
1 publication, 1.27%
|
BMFH Press
|
BMFH Press, 1, 1.27%
BMFH Press
1 publication, 1.27%
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Hans Publishers
|
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1 publication, 1.27%
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Walter de Gruyter
|
Walter de Gruyter
1 publication, 1.27%
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Bentham Science
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1 publication, 1.27%
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2
4
6
8
10
12
14
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18
20
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Abakumov M. A. et al. Toxicity of iron oxide nanoparticles: Size and coating effects // Journal of Biochemical and Molecular Toxicology. 2018. Vol. 32. No. 12. p. e22225.
GOST all authors (up to 50)
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Abakumov M. A., Semkina A. S., Skorikov A. S., Vishnevskiy D. A., Ivanova A. V., Mironova E., Davydova G. A., Majouga A. G., Чехонин В. П. Toxicity of iron oxide nanoparticles: Size and coating effects // Journal of Biochemical and Molecular Toxicology. 2018. Vol. 32. No. 12. p. e22225.
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RIS
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TY - JOUR
DO - 10.1002/jbt.22225
UR - https://doi.org/10.1002%2Fjbt.22225
TI - Toxicity of iron oxide nanoparticles: Size and coating effects
T2 - Journal of Biochemical and Molecular Toxicology
AU - Semkina, Alevtina S.
AU - Skorikov, Alexander S.
AU - Vishnevskiy, Daniil A
AU - Ivanova, Anna V.
AU - Mironova, Elena
AU - Abakumov, Maxim A.
AU - Davydova, Galina A
AU - Majouga, Alexander G.
AU - Чехонин, В. П.
PY - 2018
DA - 2018/10/05 00:00:00
PB - Wiley
SP - e22225
IS - 12
VL - 32
SN - 1095-6670
SN - 1099-0461
ER -
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@article{2018_Abakumov,
author = {Alevtina S. Semkina and Alexander S. Skorikov and Daniil A Vishnevskiy and Anna V. Ivanova and Elena Mironova and Maxim A. Abakumov and Galina A Davydova and Alexander G. Majouga and В. П. Чехонин},
title = {Toxicity of iron oxide nanoparticles: Size and coating effects},
journal = {Journal of Biochemical and Molecular Toxicology},
year = {2018},
volume = {32},
publisher = {Wiley},
month = {oct},
url = {https://doi.org/10.1002%2Fjbt.22225},
number = {12},
pages = {e22225},
doi = {10.1002/jbt.22225}
}
Cite this
MLA
Copy
Abakumov, Maxim A., et al. “Toxicity of iron oxide nanoparticles: Size and coating effects.” Journal of Biochemical and Molecular Toxicology, vol. 32, no. 12, Oct. 2018, p. e22225. https://doi.org/10.1002%2Fjbt.22225.