Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, volume 10, issue 3

Two decades of dendrimers as versatile MRI agents: a tale with and without metals.

McMahon Michael ^{1, 2}

Bulte Jeff W.M. ^{1, 2, 3, 4, 5}

Hide authors affiliations Show authors affiliations: 5 affiliations

The Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research The Johns Hopkins University School of Medicine Baltimore MD USA |

F. M. Kirby Research Center for Functional Brain Imaging Kennedy Krieger Institute Baltimore MD USA |

Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering The Johns Hopkins University School of Medicine Baltimore MD USA |

⁴

Department of Biomedical Engineering The Johns Hopkins University School of Medicine Baltimore MD USA |

⁵

Department of Oncology The Johns Hopkins University School of Medicine Baltimore MD USA |

Publication type: Journal Article

Publication date: 2017-09-11

Wiley

Journal: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Quartile SCImago

Quartile WOS

Impact factor: 8.6

ISSN: 19390041, 19395116

DOI: 10.1002/wnan.1496

Copy DOI

PubMed ID: 28895298

Medicine (miscellaneous)

Bioengineering

Biomedical Engineering

Abstract

Dendrimers or dendritic polymers are a class of compounds with great potential for nanomedical use. Some of their properties, including their rigidity, low polydispersity and the ease with which their surfaces can be modified make them particularly well suited for use as MRI diagnostic or theranostic agents. For the past 20 years, researchers have recognized this potential and refined dendrimer formulations to optimize these nanocarriers for a host of MRI applications, including blood pool imaging agents, lymph node imaging agents, tumor-targeted theranostic agents and cell tracking agents. This review summarizes the various types of dendrimers according to the type of MR contrast they can provide. This includes the metallic T1 , T2 and paraCEST imaging agents, and the non-metallic diaCEST and fluorinated (19 F) heteronuclear imaging agents. This article is categorized under: Diagnostic Tools > In Vivo Nanodiagnostics and Imaging Implantable Materials and Surgical Technologies > Nanomaterials and Implants.

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McMahon M. et al. Two decades of dendrimers as versatile MRI agents: a tale with and without metals. // Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 2017. Vol. 10. No. 3.

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McMahon M., Bulte J. W. Two decades of dendrimers as versatile MRI agents: a tale with and without metals. // Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 2017. Vol. 10. No. 3.

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RIS Copy

TY - JOUR

DO - 10.1002/wnan.1496

UR - https://doi.org/10.1002%2Fwnan.1496

TI - Two decades of dendrimers as versatile MRI agents: a tale with and without metals.

T2 - Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

AU - McMahon, Michael

AU - Bulte, Jeff W.M.

PY - 2017

DA - 2017/09/11 00:00:00

PB - Wiley

IS - 3

VL - 10

PMID - 28895298

SN - 1939-0041

SN - 1939-5116

ER -

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BibTex Copy

@article{2017_McMahon,

author = {Michael McMahon and Jeff W.M. Bulte},

title = {Two decades of dendrimers as versatile MRI agents: a tale with and without metals.},

journal = {Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology},

year = {2017},

volume = {10},

publisher = {Wiley},

month = {sep},

url = {https://doi.org/10.1002%2Fwnan.1496},

number = {3},

doi = {10.1002/wnan.1496}

}

Found error?

Publisher

Wiley

Journal

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Quartile SCImago

Quartile WOS

Impact factor

8.6

ISSN

19390041 (Print)
19395116 (Electronic)