Russian Chemical Bulletin, volume 67, issue 4, pages 600-613

Quantum dots in proteomic studies and medical diagnostics

Gladyshev P. P. 1
Tumanov Yu V 2
Ibragimova S A 1
Kouznetsov V. V. 3
Gribova E D 1
Publication typeJournal Article
Publication date2018-04-01
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor1.7
ISSN10665285, 15739171
General Chemistry
Abstract
Modern medical diagnostics requires the detection of minor amounts of target proteins at the background of numerous different biological components. With rare exception, these problems cannot be solved by purely physical research methods. In this case, the simplest and efficient approach is concerned with the principles of complementary affine interactions of biopolymers. In this case, high sensitivity of the analysis is achieved by the introduction of labels with certain physical properties in affinity bioreagents. This review is focused on the development of proteomic studies and medical diagnostics with the use of colloidal quantum dots (QDs) as labels in affinity bioreagents. This review is devoted to the description of in vitro proteomic approaches used in the studies and diagnostics, where the problem related to toxicity is not as crucial as in therapy and no restrictions on the types and composition of QDs are imposed. In this case, QDs are considered to be one of the key components of a bioanalytical system. The problems of proteomic medical diagnostics are discussed from the viewpoint of analytical chemistry with the account for the structure and properties of macromolecular analytes and appropriate bioreagents.

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Russian Chemical Bulletin
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Springer Nature
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Gladyshev P. P. et al. Quantum dots in proteomic studies and medical diagnostics // Russian Chemical Bulletin. 2018. Vol. 67. No. 4. pp. 600-613.
GOST all authors (up to 50) Copy
Gladyshev P. P., Tumanov Yu. V., Ibragimova S. A., Kouznetsov V. V., Gribova E. D. Quantum dots in proteomic studies and medical diagnostics // Russian Chemical Bulletin. 2018. Vol. 67. No. 4. pp. 600-613.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1007/s11172-018-2114-7
UR - https://doi.org/10.1007%2Fs11172-018-2114-7
TI - Quantum dots in proteomic studies and medical diagnostics
T2 - Russian Chemical Bulletin
AU - Gladyshev, P. P.
AU - Tumanov, Yu V
AU - Ibragimova, S A
AU - Kouznetsov, V. V.
AU - Gribova, E D
PY - 2018
DA - 2018/04/01 00:00:00
PB - Springer Nature
SP - 600-613
IS - 4
VL - 67
SN - 1066-5285
SN - 1573-9171
ER -
BibTex |
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BibTex Copy
@article{2018_Gladyshev,
author = {P. P. Gladyshev and Yu V Tumanov and S A Ibragimova and V. V. Kouznetsov and E D Gribova},
title = {Quantum dots in proteomic studies and medical diagnostics},
journal = {Russian Chemical Bulletin},
year = {2018},
volume = {67},
publisher = {Springer Nature},
month = {apr},
url = {https://doi.org/10.1007%2Fs11172-018-2114-7},
number = {4},
pages = {600--613},
doi = {10.1007/s11172-018-2114-7}
}
MLA
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MLA Copy
Gladyshev, P. P., et al. “Quantum dots in proteomic studies and medical diagnostics.” Russian Chemical Bulletin, vol. 67, no. 4, Apr. 2018, pp. 600-613. https://doi.org/10.1007%2Fs11172-018-2114-7.
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