Russian Chemical Bulletin, volume 67, issue 4, pages 614-623
Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics
Publication type: Journal Article
Publication date: 2018-04-01
Journal:
Russian Chemical Bulletin
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor: 1.7
ISSN: 10665285, 15739171
General Chemistry
Abstract
The methods of the fabrication of polymers based on aspartic and glutamic acids as monomers are reviewed. The methods are perspective from the viewpoint of green chemistry and economics. Actual tendencies existing in the application of the polymers in medicinal chemistry and pharmaceutics are also considered. The results of using mentioned polymers of amino acids to obtain stable nanosized enzymatic complex drugs, based on organophosphate hydrolase and possessing both antibacterial and antineurotoxic action are presented. The drugs are effective destructors of N-acyl homoserine lactones, playing the role of signaling molecules for the quorum response of gram-negative bacteria. These enzymatic-polymer complexes in combination with well-known antibiotics reduce antimicrobial doses inhibiting growth of the pathogens.
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Citations by publishers
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1 publication, 7.69%
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1 publication, 7.69%
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American Chemical Society (ACS)
1 publication, 7.69%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Maslova O. V., Senko O. V., Efremenko E. N. Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics // Russian Chemical Bulletin. 2018. Vol. 67. No. 4. pp. 614-623.
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Maslova O. V., Senko O. V., Efremenko E. N. Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics // Russian Chemical Bulletin. 2018. Vol. 67. No. 4. pp. 614-623.
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TY - JOUR
DO - 10.1007/s11172-018-2115-6
UR - https://doi.org/10.1007%2Fs11172-018-2115-6
TI - Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics
T2 - Russian Chemical Bulletin
AU - Maslova, O. V.
AU - Senko, O V
AU - Efremenko, E N
PY - 2018
DA - 2018/04/01 00:00:00
PB - Springer Nature
SP - 614-623
IS - 4
VL - 67
SN - 1066-5285
SN - 1573-9171
ER -
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@article{2018_Maslova
author = {O. V. Maslova and O V Senko and E N Efremenko},
title = {Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics},
journal = {Russian Chemical Bulletin},
year = {2018},
volume = {67},
publisher = {Springer Nature},
month = {apr},
url = {https://doi.org/10.1007%2Fs11172-018-2115-6},
number = {4},
pages = {614--623},
doi = {10.1007/s11172-018-2115-6}
}
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MLA
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Maslova, O. V., et al. “Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics.” Russian Chemical Bulletin, vol. 67, no. 4, Apr. 2018, pp. 614-623. https://doi.org/10.1007%2Fs11172-018-2115-6.