Russian Chemical Bulletin, volume 67, issue 4, pages 614-623

Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics

Publication typeJournal Article
Publication date2018-04-01
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor1.7
ISSN10665285, 15739171
General Chemistry
Abstract
The methods of the fabrication of polymers based on aspartic and glutamic acids as monomers are reviewed. The methods are perspective from the viewpoint of green chemistry and economics. Actual tendencies existing in the application of the polymers in medicinal chemistry and pharmaceutics are also considered. The results of using mentioned polymers of amino acids to obtain stable nanosized enzymatic complex drugs, based on organophosphate hydrolase and possessing both antibacterial and antineurotoxic action are presented. The drugs are effective destructors of N-acyl homoserine lactones, playing the role of signaling molecules for the quorum response of gram-negative bacteria. These enzymatic-polymer complexes in combination with well-known antibiotics reduce antimicrobial doses inhibiting growth of the pathogens.

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Maslova O. V., Senko O. V., Efremenko E. N. Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics // Russian Chemical Bulletin. 2018. Vol. 67. No. 4. pp. 614-623.
GOST all authors (up to 50) Copy
Maslova O. V., Senko O. V., Efremenko E. N. Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics // Russian Chemical Bulletin. 2018. Vol. 67. No. 4. pp. 614-623.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s11172-018-2115-6
UR - https://doi.org/10.1007%2Fs11172-018-2115-6
TI - Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics
T2 - Russian Chemical Bulletin
AU - Maslova, O. V.
AU - Senko, O V
AU - Efremenko, E N
PY - 2018
DA - 2018/04/01 00:00:00
PB - Springer Nature
SP - 614-623
IS - 4
VL - 67
SN - 1066-5285
SN - 1573-9171
ER -
BibTex |
Cite this
BibTex Copy
@article{2018_Maslova
author = {O. V. Maslova and O V Senko and E N Efremenko},
title = {Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics},
journal = {Russian Chemical Bulletin},
year = {2018},
volume = {67},
publisher = {Springer Nature},
month = {apr},
url = {https://doi.org/10.1007%2Fs11172-018-2115-6},
number = {4},
pages = {614--623},
doi = {10.1007/s11172-018-2115-6}
}
MLA
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MLA Copy
Maslova, O. V., et al. “Aspartic and glutamic acids polymers: preparation and applications in medicinal chemistry and pharmaceutics.” Russian Chemical Bulletin, vol. 67, no. 4, Apr. 2018, pp. 614-623. https://doi.org/10.1007%2Fs11172-018-2115-6.
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