1,2,4-Thiadiazoles

In the present chapter, the synthesis, characterization and application of 1,2,4-thiadiazoles is compiled. New insights in structural properties obtained from spectroscopy are reported and information about thermodynamic aspects is updated. The chapter also covers current research about reactivity of 1,2,4-thidiazoles including reactions of the basic ring framework and substituents. Furthermore, new synthetic methods to build up 1,2,4-thiadiazoles are described. The last section briefly summarizes applications and important compounds based on 1,2,4-thiadiazoles.