том 133 страницы 56-61

Cytotoxic and antibacterial triterpenoids from the roots of Morinda officinalis var. officinalis

Hui Juan Zhai 1, 2
JINHAI YU 2
Jin Zhai 2
Hai-Shan Liu 2
Junsheng Zhang 2
Xiu-Qing Song 1, 2
Yuying Zhang 2
Hua Zhang 2
1
 
School of Chemistry and Chemical Engineering, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan 250022, China
2
 
School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan 250022, China.
Тип публикацииJournal Article
Дата публикации2019-03-01
scimago Q2
wos Q3
БС2
SJR0.537
CiteScore3.9
Impact factor2.6
ISSN0367326X, 18736971
Drug Discovery
General Medicine
Pharmacology
Краткое описание
Seven new pentacyclic triterpenoids including six ursane-type, marinoids A-F (1-6), and one oleanane-type, marinoid G (7), along with five known analogues (8-12), were separated from the roots of Morinda officinalis var. officinalis. Their structures were assigned by spectroscopic means especially analysis of 2D NMR data, with the absolute configurations of 1 and 2 being determined via comparison of their experimental ECD spectra with the computed ones. Selective compounds displayed cytotoxic activity against two human osteosarcoma cell lines and also antibacterial effects against one Gram positive and one Gram negative strains.
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Zhai H. J. et al. Cytotoxic and antibacterial triterpenoids from the roots of Morinda officinalis var. officinalis // Fitoterapia. 2019. Vol. 133. pp. 56-61.
ГОСТ со всеми авторами (до 50) Скопировать
Zhai H. J., YU J., Zhai J., Liu H., Zhang J., Song X., Zhang Y., Zhang H. Cytotoxic and antibacterial triterpenoids from the roots of Morinda officinalis var. officinalis // Fitoterapia. 2019. Vol. 133. pp. 56-61.
RIS |
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TY - JOUR
DO - 10.1016/j.fitote.2018.12.011
UR - https://doi.org/10.1016/j.fitote.2018.12.011
TI - Cytotoxic and antibacterial triterpenoids from the roots of Morinda officinalis var. officinalis
T2 - Fitoterapia
AU - Zhai, Hui Juan
AU - YU, JINHAI
AU - Zhai, Jin
AU - Liu, Hai-Shan
AU - Zhang, Junsheng
AU - Song, Xiu-Qing
AU - Zhang, Yuying
AU - Zhang, Hua
PY - 2019
DA - 2019/03/01
PB - Elsevier
SP - 56-61
VL - 133
PMID - 30579769
SN - 0367-326X
SN - 1873-6971
ER -
BibTex
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@article{2019_Zhai,
author = {Hui Juan Zhai and JINHAI YU and Jin Zhai and Hai-Shan Liu and Junsheng Zhang and Xiu-Qing Song and Yuying Zhang and Hua Zhang},
title = {Cytotoxic and antibacterial triterpenoids from the roots of Morinda officinalis var. officinalis},
journal = {Fitoterapia},
year = {2019},
volume = {133},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.fitote.2018.12.011},
pages = {56--61},
doi = {10.1016/j.fitote.2018.12.011}
}