Studies in Natural Products Chemistry, pages 385-441

Amicoumacins and Related Compounds: Chemistry and Biology

Publication typeBook Chapter
Publication date2018-01-01
Quartile SCImago
Quartile WOS
Impact factor
ISSN15725995
Abstract
The review will cover main classes of 3,4-dihydroisocoumarin-derived natural and bioactive compounds with main focus on antibiotics, amicoumacins and xenocoumacins. The 3,4-dihydroisocoumarin natural compounds were reviewed many years ago (Hill, 1986 [2]; McInerney and Taylor, 1995 [7]). The recent short account on amicoumacins is in Chinese and does not contain any synthetic data (Han et al., 2013 [23]). Amicoumacins A, B, and C, although discovered in the early 1980s, recently attracted attention of researchers again. These compounds have antibacterial, antiinflammatory, antiulcer (gastroprotective), herbicidal, and cytotoxic activity. Their potent antiulcerogenic action without any anticholinergic and antihistaminergic effects is the most attractive feature of this unique class of drugs. Recently, the researchers made insight into 3,4-dihydroisocoumarin and amicoumacin biosynthesis (Li et al., 2012, 2015 , ; Reimer et al., 2011 [46]; Sun et al., 2012 [80]). An impressive progress is achieved in the chemical synthesis of 3,4-dihydroisocoumarin antibiotics (Enomoto and Kuwahara, 2009, 2009 , ; Rao et al., 2014 [99]; Suzuki et al., 2015 [100]). New amicoumacin-related bioactive compounds are isolated and characterized (Bai et al., 2014 [45]; Liu et al., 2013 [42]). Recent biochemical studies revealed that amicoumacin belongs to a new class of protein synthesis inhibitors that binds to the ribosome (Lama et al., 2012 [51]; Polikanov et al., 2014 [81]). Thus, studies on amicoumacin family members undergo a renaissance, and an account on their recent chemistry and biology would be useful and well timed.

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Tyurin A. P. et al. Amicoumacins and Related Compounds: Chemistry and Biology // Studies in Natural Products Chemistry. 2018. pp. 385-441.
GOST all authors (up to 50) Copy
Tyurin A. P., Efimenko T. A., Prokhorenko I. A., Rogozhin E. A., Malanicheva I. A., Zenkova V. A., Ефременкова О. В., Korshun V. A. Amicoumacins and Related Compounds: Chemistry and Biology // Studies in Natural Products Chemistry. 2018. pp. 385-441.
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TY - GENERIC
DO - 10.1016/B978-0-444-64068-0.00012-7
UR - https://doi.org/10.1016%2FB978-0-444-64068-0.00012-7
TI - Amicoumacins and Related Compounds: Chemistry and Biology
T2 - Studies in Natural Products Chemistry
AU - Tyurin, Anton P
AU - Efimenko, T A
AU - Prokhorenko, Igor A
AU - Rogozhin, E. A.
AU - Malanicheva, I. A.
AU - Zenkova, Valentina A
AU - Ефременкова, О. В.
AU - Korshun, Vladimir A.
PY - 2018
DA - 2018/01/01 00:00:00
PB - Elsevier
SP - 385-441
SN - 1572-5995
ER -
BibTex
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BibTex Copy
@incollection{2018_Tyurin,
author = {Anton P Tyurin and T A Efimenko and Igor A Prokhorenko and E. A. Rogozhin and I. A. Malanicheva and Valentina A Zenkova and О. В. Ефременкова and Vladimir A. Korshun},
title = {Amicoumacins and Related Compounds: Chemistry and Biology},
publisher = {Elsevier},
year = {2018},
pages = {385--441},
month = {jan}
}
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