Journal of Pharmaceutical and Biomedical Analysis, volume 34, issue 3, pages 501-507

Rapid HPLC method for the determination of paclitaxel in pharmaceutical forms without separation.

Badea Irinel 1
Ciutaru Dana 1
Lazar Lelia 1
Nicolescu Daniela 1
Tudose Aurel 1
1
 
Sindan Pharmaceutical Co., 11 Ion Mihalache Blvd. 78168, Bucharest, Romania
Publication typeJournal Article
Publication date2004-02-01
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor3.4
ISSN07317085, 1873264X
Drug Discovery
Spectroscopy
Pharmaceutical Science
Clinical Biochemistry
Analytical Chemistry
Abstract
A HPLC method has been developed for the in-process determination of the paclitaxel from dosage pharmaceutical forms. This method ensures the rapid determination of paclitaxel in the presence of polyoxyl castor oil--the main constituent of paclitaxel's clinical formulation vehicle. The method is simple and rapid and does not require any preliminary treatment of the sample. The method was fully validated.

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GOST |
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GOST Copy
Badea I. et al. Rapid HPLC method for the determination of paclitaxel in pharmaceutical forms without separation. // Journal of Pharmaceutical and Biomedical Analysis. 2004. Vol. 34. No. 3. pp. 501-507.
GOST all authors (up to 50) Copy
Badea I., Ciutaru D., Lazar L., Nicolescu D., Tudose A. Rapid HPLC method for the determination of paclitaxel in pharmaceutical forms without separation. // Journal of Pharmaceutical and Biomedical Analysis. 2004. Vol. 34. No. 3. pp. 501-507.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/S0731-7085(03)00628-9
UR - https://doi.org/10.1016%2FS0731-7085%2803%2900628-9
TI - Rapid HPLC method for the determination of paclitaxel in pharmaceutical forms without separation.
T2 - Journal of Pharmaceutical and Biomedical Analysis
AU - Badea, Irinel
AU - Ciutaru, Dana
AU - Lazar, Lelia
AU - Nicolescu, Daniela
AU - Tudose, Aurel
PY - 2004
DA - 2004/02/01 00:00:00
PB - Elsevier
SP - 501-507
IS - 3
VL - 34
SN - 0731-7085
SN - 1873-264X
ER -
BibTex |
Cite this
BibTex Copy
@article{2004_Badea,
author = {Irinel Badea and Dana Ciutaru and Lelia Lazar and Daniela Nicolescu and Aurel Tudose},
title = {Rapid HPLC method for the determination of paclitaxel in pharmaceutical forms without separation.},
journal = {Journal of Pharmaceutical and Biomedical Analysis},
year = {2004},
volume = {34},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016%2FS0731-7085%2803%2900628-9},
number = {3},
pages = {501--507},
doi = {10.1016/S0731-7085(03)00628-9}
}
MLA
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MLA Copy
Badea, Irinel, et al. “Rapid HPLC method for the determination of paclitaxel in pharmaceutical forms without separation..” Journal of Pharmaceutical and Biomedical Analysis, vol. 34, no. 3, Feb. 2004, pp. 501-507. https://doi.org/10.1016%2FS0731-7085%2803%2900628-9.
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