Open Access
Open access
The Lancet Oncology, volume 18, issue 11, pages e653-e706

Future cancer research priorities in the USA: a Lancet Oncology Commission

Jaffee Elizabeth
Dang Chi Van
Agus David
Alexander B.
Kenneth C. Anderson (2) Kenneth R.
Ashworth Alan
Barker Anna D
Bastani Roshan
Bhatia Sangeeta N.
BLUESTONE JEFFREY A.
Brawley Otis W.
Butte A.
Coit Daniel G.
Davidson Nancy E.
Davis Mark E.
DEPINHO RONALD A.
Diasio Robert B.
Draetta Giulio F.
Frazier Lindsay
Futreal P. Andrew
Gambhir Sam S.
Ganz Patricia A.
Garraway Levi A.
Gerson S.
Gupta Sumit
Heath J. P.
Hoffman Ruth I
Hudis Cliff
Halbert Chanita Hughes
Ibrahim Ramy
Jadvar Hossein
Kavanagh Brian D.
Lippman Scott M
Mankoff David A.
Mardis Elaine R.
Mayer Deborah K.
McMasters Kelly M.
Meropol Neal J.
Mitchell Beverly S.
Naredi Peter
Ornish Dean
Diaz Adrian
Peppercorn Jeff
Raghavan Derek
Ritchie Christine
Schwarz Sally W.
Sullivan Richard F.
WAHL RICHARD L
Wolchok Jedd D.
Wong Sandra L.
YUNG ALFRED
Publication typeJournal Article
Publication date2017-11-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor51.1
ISSN14702045, 14745488
Oncology
Abstract
We are in the midst of a technological revolution that is providing new insights into human biology and cancer. In this era of big data, we are amassing large amounts of information that is transforming how we approach cancer treatment and prevention. Enactment of the Cancer Moonshot within the 21st Century Cures Act in the USA arrived at a propitious moment in the advancement of knowledge, providing nearly US$2 billion of funding for cancer research and precision medicine. In 2016, the Blue Ribbon Panel (BRP) set out a roadmap of recommendations designed to exploit new advances in cancer diagnosis, prevention, and treatment. Those recommendations provided a high-level view of how to accelerate the conversion of new scientific discoveries into effective treatments and prevention for cancer. The US National Cancer Institute is already implementing some of those recommendations. As experts in the priority areas identified by the BRP, we bolster those recommendations to implement this important scientific roadmap. In this Commission, we examine the BRP recommendations in greater detail and expand the discussion to include additional priority areas, including surgical oncology, radiation oncology, imaging, health systems and health disparities, regulation and financing, population science, and oncopolicy. We prioritise areas of research in the USA that we believe would accelerate efforts to benefit patients with cancer. Finally, we hope the recommendations in this report will facilitate new international collaborations to further enhance global efforts in cancer control.

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GOST |
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GOST Copy
Jaffee E. et al. Future cancer research priorities in the USA: a Lancet Oncology Commission // The Lancet Oncology. 2017. Vol. 18. No. 11. p. e653-e706.
GOST all authors (up to 50) Copy
Jaffee E. et al. Future cancer research priorities in the USA: a Lancet Oncology Commission // The Lancet Oncology. 2017. Vol. 18. No. 11. p. e653-e706.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/S1470-2045(17)30698-8
UR - https://doi.org/10.1016%2FS1470-2045%2817%2930698-8
TI - Future cancer research priorities in the USA: a Lancet Oncology Commission
T2 - The Lancet Oncology
AU - Jaffee, Elizabeth
AU - Dang, Chi Van
AU - Agus, David
AU - Alexander, B.
AU - Kenneth C. Anderson (2), Kenneth R.
AU - Ashworth, Alan
AU - Barker, Anna D
AU - Bastani, Roshan
AU - Bhatia, Sangeeta N.
AU - BLUESTONE, JEFFREY A.
AU - Brawley, Otis W.
AU - Butte, A.
AU - Coit, Daniel G.
AU - Davidson, Nancy E.
AU - Davis, Mark E.
AU - DEPINHO, RONALD A.
AU - Diasio, Robert B.
AU - Draetta, Giulio F.
AU - Frazier, Lindsay
AU - Futreal, P. Andrew
AU - Gambhir, Sam S.
AU - Ganz, Patricia A.
AU - Garraway, Levi A.
AU - Gerson, S.
AU - Gupta, Sumit
AU - Heath, J. P.
AU - Hoffman, Ruth I
AU - Hudis, Cliff
AU - Halbert, Chanita Hughes
AU - Ibrahim, Ramy
AU - Jadvar, Hossein
AU - Kavanagh, Brian D.
AU - Kittles, Rick
AU - Le, Quynh Thu
AU - Lippman, Scott M
AU - Mankoff, David A.
AU - Mardis, Elaine R.
AU - Mayer, Deborah K.
AU - McMasters, Kelly M.
AU - Meropol, Neal J.
AU - Mitchell, Beverly S.
AU - Naredi, Peter
AU - Ornish, Dean
AU - Diaz, Adrian
AU - Peppercorn, Jeff
AU - Pomper, Martin
AU - Raghavan, Derek
AU - Ritchie, Christine
AU - Schwarz, Sally W.
AU - Sullivan, Richard F.
AU - WAHL, RICHARD L
AU - Wolchok, Jedd D.
AU - Wong, Sandra L.
AU - YUNG, ALFRED
PY - 2017
DA - 2017/11/01 00:00:00
PB - Elsevier
SP - e653-e706
IS - 11
VL - 18
PMID - 29208398
SN - 1470-2045
SN - 1474-5488
ER -
BibTex |
Cite this
BibTex Copy
@article{2017_Jaffee,
author = {Elizabeth Jaffee and Chi Van Dang and David Agus and B. Alexander and Kenneth R. Kenneth C. Anderson (2) and Alan Ashworth and Anna D Barker and Roshan Bastani and Sangeeta N. Bhatia and JEFFREY A. BLUESTONE and Otis W. Brawley and A. Butte and Daniel G. Coit and Nancy E. Davidson and Mark E. Davis and RONALD A. DEPINHO and Robert B. Diasio and Giulio F. Draetta and Lindsay Frazier and P. Andrew Futreal and Sam S. Gambhir and Patricia A. Ganz and Levi A. Garraway and S. Gerson and Sumit Gupta and J. P. Heath and Ruth I Hoffman and Cliff Hudis and Chanita Hughes Halbert and Ramy Ibrahim and Hossein Jadvar and Brian D. Kavanagh and Rick Kittles and Quynh Thu Le and Scott M Lippman and David A. Mankoff and Elaine R. Mardis and Deborah K. Mayer and Kelly M. McMasters and Neal J. Meropol and Beverly S. Mitchell and Peter Naredi and Dean Ornish and Adrian Diaz and Jeff Peppercorn and Martin Pomper and Derek Raghavan and Christine Ritchie and Sally W. Schwarz and Richard F. Sullivan and RICHARD L WAHL and Jedd D. Wolchok and Sandra L. Wong and ALFRED YUNG},
title = {Future cancer research priorities in the USA: a Lancet Oncology Commission},
journal = {The Lancet Oncology},
year = {2017},
volume = {18},
publisher = {Elsevier},
month = {nov},
url = {https://doi.org/10.1016%2FS1470-2045%2817%2930698-8},
number = {11},
pages = {e653--e706},
doi = {10.1016/S1470-2045(17)30698-8}
}
MLA
Cite this
MLA Copy
Jaffee, Elizabeth, et al. “Future cancer research priorities in the USA: a Lancet Oncology Commission.” The Lancet Oncology, vol. 18, no. 11, Nov. 2017, pp. e653-e706. https://doi.org/10.1016%2FS1470-2045%2817%2930698-8.
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