Advanced Drug Delivery Reviews, volume 122, pages 20-30

The battle of “nano” paclitaxel

Sofias Alexandros Marios ^{1, 2}

Dunne Mike ³

Storm Gert ²

Allen Christine ¹

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University Of Toronto |

UTRECHT UNIVERSITY |

Leslie Dan Faculty of Pharmacy, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada. |

Publication type: Journal Article

Publication date: 2017-12-01

Elsevier

Journal: Advanced Drug Delivery Reviews

Quartile SCImago

Quartile WOS

Impact factor: 16.1

ISSN: 0169409X, 18728294

DOI: 10.1016/j.addr.2017.02.003

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Pharmaceutical Science

Abstract

Paclitaxel (PTX) is one of the three most widely used chemotherapeutic agents, together with doxorubicin and cisplatin, and is first or second line treatment for several types of cancers. In 2000, Taxol, the conventional formulation of PTX, became the best-selling cancer drug of all time with annual sales of 1.6 billion. In 2005, the introduction of the albumin-based formulation of PTX, known as Abraxane, ended Taxol's monopoly of the PTX market. Abraxane's ability to push the Taxol innovator and generic formulations aside attracted fierce competition amongst competitors worldwide to develop their own unique, new and improved formulation of PTX. At this time there are at least 18 companies focused on pre-clinical and/or clinical development of nano-formulations of PTX. These pharmaceutical companies are investing substantial capital to capture a share of the lucrative global PTX market. It is hoped that any formulation that dominates the market will result in tangible benefits to patients in terms of both survival and quality of life. Given all of this activity, here we address the question: Who is going to win the battle of "nano" paclitaxel?

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Citations by journals

	2 4 6 8 10 12
Journal of Controlled Release	Journal of Controlled Release, 11, 4.35% Journal of Controlled Release 11 publications, 4.35%
Molecules	Molecules, 7, 2.77% Molecules 7 publications, 2.77%
Advanced Drug Delivery Reviews	Advanced Drug Delivery Reviews, 7, 2.77% Advanced Drug Delivery Reviews 7 publications, 2.77%
International Journal of Pharmaceutics	International Journal of Pharmaceutics, 6, 2.37% International Journal of Pharmaceutics 6 publications, 2.37%
Nanomedicine	Nanomedicine, 5, 1.98% Nanomedicine 5 publications, 1.98%
Pharmaceutics	Pharmaceutics, 5, 1.98% Pharmaceutics 5 publications, 1.98%
Journal of Drug Delivery Science and Technology	Journal of Drug Delivery Science and Technology, 5, 1.98% Journal of Drug Delivery Science and Technology 5 publications, 1.98%
ACS applied materials & interfaces	ACS applied materials & interfaces, 5, 1.98% ACS applied materials & interfaces 5 publications, 1.98%
Journal of Materials Chemistry B	Journal of Materials Chemistry B, 5, 1.98% Journal of Materials Chemistry B 5 publications, 1.98%
Nano Research	Nano Research, 4, 1.58% Nano Research 4 publications, 1.58%
Cancers	Cancers, 4, 1.58% Cancers 4 publications, 1.58%
Frontiers in Pharmacology	Frontiers in Pharmacology, 4, 1.58% Frontiers in Pharmacology 4 publications, 1.58%
Journal of Nanobiotechnology	Journal of Nanobiotechnology, 4, 1.58% Journal of Nanobiotechnology 4 publications, 1.58%
Acta Pharmaceutica Sinica B	Acta Pharmaceutica Sinica B, 4, 1.58% Acta Pharmaceutica Sinica B 4 publications, 1.58%
ACS Biomaterials Science and Engineering	ACS Biomaterials Science and Engineering, 4, 1.58% ACS Biomaterials Science and Engineering 4 publications, 1.58%
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology	Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 4, 1.58% Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 4 publications, 1.58%
Nano Letters	Nano Letters, 3, 1.19% Nano Letters 3 publications, 1.19%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 3, 1.19% International Journal of Molecular Sciences 3 publications, 1.19%
Polymers	Polymers, 3, 1.19% Polymers 3 publications, 1.19%
Pharmaceutical Research	Pharmaceutical Research, 3, 1.19% Pharmaceutical Research 3 publications, 1.19%
Colloids and Surfaces B: Biointerfaces	Colloids and Surfaces B: Biointerfaces, 3, 1.19% Colloids and Surfaces B: Biointerfaces 3 publications, 1.19%
Biomedicine and Pharmacotherapy	Biomedicine and Pharmacotherapy, 3, 1.19% Biomedicine and Pharmacotherapy 3 publications, 1.19%
Nanomedicine: Nanotechnology, Biology, and Medicine	Nanomedicine: Nanotechnology, Biology, and Medicine, 3, 1.19% Nanomedicine: Nanotechnology, Biology, and Medicine 3 publications, 1.19%
Biomacromolecules	Biomacromolecules, 3, 1.19% Biomacromolecules 3 publications, 1.19%
Drug Delivery	Drug Delivery, 3, 1.19% Drug Delivery 3 publications, 1.19%
Evidence-based Complementary and Alternative Medicine	Evidence-based Complementary and Alternative Medicine, 3, 1.19% Evidence-based Complementary and Alternative Medicine 3 publications, 1.19%
Frontiers in Plant Science	Frontiers in Plant Science, 2, 0.79% Frontiers in Plant Science 2 publications, 0.79%
Current Medicinal Chemistry	Current Medicinal Chemistry, 2, 0.79% Current Medicinal Chemistry 2 publications, 0.79%
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	2 4 6 8 10 12

Citations by publishers

	10 20 30 40 50 60 70
Elsevier	Elsevier, 70, 27.67% Elsevier 70 publications, 27.67%
American Chemical Society (ACS)	American Chemical Society (ACS), 28, 11.07% American Chemical Society (ACS) 28 publications, 11.07%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 28, 11.07% Multidisciplinary Digital Publishing Institute (MDPI) 28 publications, 11.07%
Springer Nature	Springer Nature, 26, 10.28% Springer Nature 26 publications, 10.28%
Wiley	Wiley, 18, 7.11% Wiley 18 publications, 7.11%
Taylor & Francis	Taylor & Francis, 12, 4.74% Taylor & Francis 12 publications, 4.74%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 11, 4.35% Royal Society of Chemistry (RSC) 11 publications, 4.35%
Frontiers Media S.A.	Frontiers Media S.A., 9, 3.56% Frontiers Media S.A. 9 publications, 3.56%
Future Medicine	Future Medicine, 6, 2.37% Future Medicine 6 publications, 2.37%
Bentham Science	Bentham Science, 5, 1.98% Bentham Science 5 publications, 1.98%
Dove Medical Press	Dove Medical Press, 4, 1.58% Dove Medical Press 4 publications, 1.58%
IOP Publishing	IOP Publishing, 3, 1.19% IOP Publishing 3 publications, 1.19%
Hindawi Limited	Hindawi Limited, 3, 1.19% Hindawi Limited 3 publications, 1.19%
SAGE	SAGE, 2, 0.79% SAGE 2 publications, 0.79%
Spandidos Publications	Spandidos Publications, 2, 0.79% Spandidos Publications 2 publications, 0.79%
Center of Pharmaceutical Analytics Ltd	Center of Pharmaceutical Analytics Ltd, 1, 0.4% Center of Pharmaceutical Analytics Ltd 1 publication, 0.4%
American Scientific Publishers	American Scientific Publishers, 1, 0.4% American Scientific Publishers 1 publication, 0.4%
Pleiades Publishing	Pleiades Publishing, 1, 0.4% Pleiades Publishing 1 publication, 0.4%
Institution of Engineering and Technology (IET)	Institution of Engineering and Technology (IET), 1, 0.4% Institution of Engineering and Technology (IET) 1 publication, 0.4%
World Scientific	World Scientific, 1, 0.4% World Scientific 1 publication, 0.4%
International Dose-Response Society	International Dose-Response Society, 1, 0.4% International Dose-Response Society 1 publication, 0.4%
Xi'an Jiaotong University	Xi'an Jiaotong University, 1, 0.4% Xi'an Jiaotong University 1 publication, 0.4%
Maruzen Co., Ltd/Maruzen Kabushikikaisha	Maruzen Co., Ltd/Maruzen Kabushikikaisha, 1, 0.4% Maruzen Co., Ltd/Maruzen Kabushikikaisha 1 publication, 0.4%
Bashkir State Medical University	Bashkir State Medical University, 1, 0.4% Bashkir State Medical University 1 publication, 0.4%
AME Publishing Company	AME Publishing Company, 1, 0.4% AME Publishing Company 1 publication, 0.4%
CSIRO Publishing	CSIRO Publishing, 1, 0.4% CSIRO Publishing 1 publication, 0.4%
	10 20 30 40 50 60 70

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Sofias A. M. et al. The battle of “nano” paclitaxel // Advanced Drug Delivery Reviews. 2017. Vol. 122. pp. 20-30.

GOST all authors (up to 50) Copy

Sofias A. M., Dunne M., Storm G., Allen C. The battle of “nano” paclitaxel // Advanced Drug Delivery Reviews. 2017. Vol. 122. pp. 20-30.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.addr.2017.02.003

UR - https://doi.org/10.1016%2Fj.addr.2017.02.003

TI - The battle of “nano” paclitaxel

T2 - Advanced Drug Delivery Reviews

AU - Sofias, Alexandros Marios

AU - Dunne, Mike

AU - Storm, Gert

AU - Allen, Christine

PY - 2017

DA - 2017/12/01 00:00:00

PB - Elsevier

SP - 20-30

VL - 122

SN - 0169-409X

SN - 1872-8294

ER -

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BibTex Copy

@article{2017_Sofias,

author = {Alexandros Marios Sofias and Mike Dunne and Gert Storm and Christine Allen},

title = {The battle of “nano” paclitaxel},

journal = {Advanced Drug Delivery Reviews},

year = {2017},

volume = {122},

publisher = {Elsevier},

month = {dec},

url = {https://doi.org/10.1016%2Fj.addr.2017.02.003},

pages = {20--30},

doi = {10.1016/j.addr.2017.02.003}

}

Found error?

Publisher

Elsevier

Journal

Advanced Drug Delivery Reviews

Quartile SCImago

Quartile WOS

Impact factor

16.1

ISSN

0169409X (Print)
18728294 (Electronic)