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Acta Pharmaceutica Sinica B, volume 11, issue 8, pages 2265-2285

Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

Zhang Mingming ¹

Gao Shan ¹

Yang Dongjuan ¹

Fang Yan ¹

Lin Xiaojie ¹

Jin Xuechao ¹

LIU Yuli ¹

Xiu Liu Xiu Liu ¹

Su Kexin ¹

Shi Kai ¹

Hide authors affiliations Show authors affiliations: 1 affiliation

Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 117004, China |

Publication type: Journal Article

Publication date: 2021-08-01

Elsevier

Journal: Acta Pharmaceutica Sinica B

Quartile SCImago

Quartile WOS

Impact factor: 14.5

ISSN: 22113835, 22113843

DOI: 10.1016/j.apsb.2021.03.033

Copy DOI

PubMed ID: 34522587

General Pharmacology, Toxicology and Pharmaceutics

Abstract

The administration of nanoparticles (NPs) first faces the challenges of evading renal filtration and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the expanded endothelial space and penetrated the dense stroma of tumor microenvironment to tumor cells. As long as possible to prolong the time of NPs remaining in tumor tissue, NPs release active agent and induce pharmacological action. This review provides a comprehensive summary of the physical and chemical properties of NPs and the influence of various biological factors in tumor microenvironment, and discusses how to improve the final efficacy through adjusting the characteristics and structure of NPs. Perspectives and future directions are also provided.

By date By citations

Citations by journals

	2 4 6 8 10
Acta Pharmaceutica Sinica B	Acta Pharmaceutica Sinica B, 10, 10.99% Acta Pharmaceutica Sinica B 10 publications, 10.99%
Pharmaceutics	Pharmaceutics, 5, 5.49% Pharmaceutics 5 publications, 5.49%
Journal of Drug Delivery Science and Technology	Journal of Drug Delivery Science and Technology, 5, 5.49% Journal of Drug Delivery Science and Technology 5 publications, 5.49%
International Journal of Nanomedicine	International Journal of Nanomedicine, 4, 4.4% International Journal of Nanomedicine 4 publications, 4.4%
Nanomaterials	Nanomaterials, 3, 3.3% Nanomaterials 3 publications, 3.3%
Molecules	Molecules, 3, 3.3% Molecules 3 publications, 3.3%
Journal of Controlled Release	Journal of Controlled Release, 3, 3.3% Journal of Controlled Release 3 publications, 3.3%
Biomedicine and Pharmacotherapy	Biomedicine and Pharmacotherapy, 3, 3.3% Biomedicine and Pharmacotherapy 3 publications, 3.3%
Gels	Gels, 2, 2.2% Gels 2 publications, 2.2%
Chinese Chemical Letters	Chinese Chemical Letters, 2, 2.2% Chinese Chemical Letters 2 publications, 2.2%
Advanced Science	Advanced Science, 2, 2.2% Advanced Science 2 publications, 2.2%
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology	Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2, 2.2% Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2 publications, 2.2%
International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 2, 2.2% International Journal of Biological Macromolecules 2 publications, 2.2%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 1, 1.1% International Journal of Molecular Sciences 1 publication, 1.1%
Cancers	Cancers, 1, 1.1% Cancers 1 publication, 1.1%
Frontiers in Toxicology	Frontiers in Toxicology, 1, 1.1% Frontiers in Toxicology 1 publication, 1.1%
Journal of Nanobiotechnology	Journal of Nanobiotechnology, 1, 1.1% Journal of Nanobiotechnology 1 publication, 1.1%
Acta Pharmacologica Sinica	Acta Pharmacologica Sinica, 1, 1.1% Acta Pharmacologica Sinica 1 publication, 1.1%
Journal of Industrial and Engineering Chemistry	Journal of Industrial and Engineering Chemistry, 1, 1.1% Journal of Industrial and Engineering Chemistry 1 publication, 1.1%
International Journal of Pharmaceutics	International Journal of Pharmaceutics, 1, 1.1% International Journal of Pharmaceutics 1 publication, 1.1%
Colloids and Surfaces B: Biointerfaces	Colloids and Surfaces B: Biointerfaces, 1, 1.1% Colloids and Surfaces B: Biointerfaces 1 publication, 1.1%
European Polymer Journal	European Polymer Journal, 1, 1.1% European Polymer Journal 1 publication, 1.1%
Biochimica et Biophysica Acta - Reviews on Cancer	Biochimica et Biophysica Acta - Reviews on Cancer, 1, 1.1% Biochimica et Biophysica Acta - Reviews on Cancer 1 publication, 1.1%
Pharmacology and Therapeutics	Pharmacology and Therapeutics, 1, 1.1% Pharmacology and Therapeutics 1 publication, 1.1%
Advanced healthcare materials	Advanced healthcare materials, 1, 1.1% Advanced healthcare materials 1 publication, 1.1%
Biomedical Materials & Devices	Biomedical Materials & Devices, 1, 1.1% Biomedical Materials & Devices 1 publication, 1.1%
Current Cancer Drug Targets	Current Cancer Drug Targets, 1, 1.1% Current Cancer Drug Targets 1 publication, 1.1%
Molecular Pharmaceutics	Molecular Pharmaceutics, 1, 1.1% Molecular Pharmaceutics 1 publication, 1.1%
Drug Delivery	Drug Delivery, 1, 1.1% Drug Delivery 1 publication, 1.1%
	2 4 6 8 10

Citations by publishers

	5 10 15 20 25 30 35
Elsevier	Elsevier, 35, 38.46% Elsevier 35 publications, 38.46%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 16, 17.58% Multidisciplinary Digital Publishing Institute (MDPI) 16 publications, 17.58%
Springer Nature	Springer Nature, 10, 10.99% Springer Nature 10 publications, 10.99%
Wiley	Wiley, 7, 7.69% Wiley 7 publications, 7.69%
American Chemical Society (ACS)	American Chemical Society (ACS), 6, 6.59% American Chemical Society (ACS) 6 publications, 6.59%
Dove Medical Press	Dove Medical Press, 4, 4.4% Dove Medical Press 4 publications, 4.4%
Frontiers Media S.A.	Frontiers Media S.A., 1, 1.1% Frontiers Media S.A. 1 publication, 1.1%
Korean Society of Industrial Engineering Chemistry	Korean Society of Industrial Engineering Chemistry, 1, 1.1% Korean Society of Industrial Engineering Chemistry 1 publication, 1.1%
Bentham Science	Bentham Science, 1, 1.1% Bentham Science 1 publication, 1.1%
Taylor & Francis	Taylor & Francis, 1, 1.1% Taylor & Francis 1 publication, 1.1%
Oxford University Press	Oxford University Press, 1, 1.1% Oxford University Press 1 publication, 1.1%
IntechOpen	IntechOpen, 1, 1.1% IntechOpen 1 publication, 1.1%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 1.1% Royal Society of Chemistry (RSC) 1 publication, 1.1%
	5 10 15 20 25 30 35

We do not take into account publications that without a DOI.
Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
Statistics recalculated weekly.

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Zhang M. et al. Influencing factors and strategies of enhancing nanoparticles into tumors in vivo // Acta Pharmaceutica Sinica B. 2021. Vol. 11. No. 8. pp. 2265-2285.

GOST all authors (up to 50) Copy

Zhang M., Gao S., Yang D., Fang Y., Lin X., Jin X., LIU Y., Xiu Liu X. L., Su K., Shi K. Influencing factors and strategies of enhancing nanoparticles into tumors in vivo // Acta Pharmaceutica Sinica B. 2021. Vol. 11. No. 8. pp. 2265-2285.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.apsb.2021.03.033

UR - https://doi.org/10.1016%2Fj.apsb.2021.03.033

TI - Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

T2 - Acta Pharmaceutica Sinica B

AU - Zhang, Mingming

AU - Gao, Shan

AU - Yang, Dongjuan

AU - Fang, Yan

AU - Lin, Xiaojie

AU - Jin, Xuechao

AU - LIU, Yuli

AU - Xiu Liu, Xiu Liu

AU - Su, Kexin

AU - Shi, Kai

PY - 2021

DA - 2021/08/01 00:00:00

PB - Elsevier

SP - 2265-2285

IS - 8

VL - 11

PMID - 34522587

SN - 2211-3835

SN - 2211-3843

ER -

BibTex |

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BibTex Copy

@article{2021_Zhang,

author = {Mingming Zhang and Shan Gao and Dongjuan Yang and Yan Fang and Xiaojie Lin and Xuechao Jin and Yuli LIU and Xiu Liu Xiu Liu and Kexin Su and Kai Shi},

title = {Influencing factors and strategies of enhancing nanoparticles into tumors in vivo},

journal = {Acta Pharmaceutica Sinica B},

year = {2021},

volume = {11},

publisher = {Elsevier},

month = {aug},

url = {https://doi.org/10.1016%2Fj.apsb.2021.03.033},

number = {8},

pages = {2265--2285},

doi = {10.1016/j.apsb.2021.03.033}

}

MLA

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MLA Copy

Zhang, Mingming, et al. “Influencing factors and strategies of enhancing nanoparticles into tumors in vivo.” Acta Pharmaceutica Sinica B, vol. 11, no. 8, Aug. 2021, pp. 2265-2285. https://doi.org/10.1016%2Fj.apsb.2021.03.033.

Found error?

Publisher

Elsevier

Journal

Acta Pharmaceutica Sinica B

Quartile SCImago

Quartile WOS

Impact factor

14.5

ISSN

22113835 (Print)
22113843 (Electronic)