Coordination Chemistry Reviews, volume 280, pages 84-95

Applications of five-membered ring products of cyclometalation reactions as anticancer agents

Omae Iwao ¹

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Omae Research Laboratories, 335-23 Mizuno, Sayama, Saitama Prefecture, 350-1317, Japan |

Publication type: Journal Article

Publication date: 2014-11-01

Elsevier

Journal: Coordination Chemistry Reviews

Quartile SCImago

Quartile WOS

Impact factor: 20.6

ISSN: 00108545

DOI: 10.1016/j.ccr.2014.07.019

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Materials Chemistry

Inorganic Chemistry

Physical and Theoretical Chemistry

Abstract

The use of metal compounds as anticancer agents is one of the applications of the five-membered ring products of cyclometalation reactions, including those with Pt, Pd, Rh, Ir, Ru, Os and Au. The coordinating atoms in these anticancer agents are mainly N and, in very few cases, P, S and O. The substrates used for these cyclometalation reactions are mainly pyridine ring compounds, such as 2-phenylpyridines, benzo[ h ]quinolines, 2,6-diphenylpyridines and so on. The ancillary ligands used are bipyridines, 1,10-phenathrolines, 2,6-bispyridylpyridine, N -heterocyclic carbenes and so on. The platinum compounds of 2,6-phenylpyridylpyridine CNN pincer N -heterocyclic carbene, the gold compounds of 2,6-diphenylpyridine CNC pincer alkylphosphine or N -heterocarbene, and the osmium compounds of 2-phenylpyridine, phenyloxazole, m -bispyridylbenzenes cyclometalated 1,10-phenanthrolines or 2,6-bispyridylpyridines show very high cytotoxicity values compared to those of cisplatin.

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Citations by journals

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Journal of Organometallic Chemistry	Journal of Organometallic Chemistry, 16, 17.02% Journal of Organometallic Chemistry 16 publications, 17.02%
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Chemistry - A European Journal	Chemistry - A European Journal, 5, 5.32% Chemistry - A European Journal 5 publications, 5.32%
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Journal of Medicinal Chemistry	Journal of Medicinal Chemistry, 3, 3.19% Journal of Medicinal Chemistry 3 publications, 3.19%
Chemical Communications	Chemical Communications, 3, 3.19% Chemical Communications 3 publications, 3.19%
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Molecules	Molecules, 2, 2.13% Molecules 2 publications, 2.13%
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ACS Omega	ACS Omega, 2, 2.13% ACS Omega 2 publications, 2.13%
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BioMetals	BioMetals, 1, 1.06% BioMetals 1 publication, 1.06%
Journal of the Iranian Chemical Society	Journal of the Iranian Chemical Society, 1, 1.06% Journal of the Iranian Chemical Society 1 publication, 1.06%
Medicinal Chemistry Research	Medicinal Chemistry Research, 1, 1.06% Medicinal Chemistry Research 1 publication, 1.06%
Journal of Chemical Sciences	Journal of Chemical Sciences, 1, 1.06% Journal of Chemical Sciences 1 publication, 1.06%
Journal of Catalysis	Journal of Catalysis, 1, 1.06% Journal of Catalysis 1 publication, 1.06%
Journal of Industrial and Engineering Chemistry	Journal of Industrial and Engineering Chemistry, 1, 1.06% Journal of Industrial and Engineering Chemistry 1 publication, 1.06%
Journal of Inorganic Biochemistry	Journal of Inorganic Biochemistry, 1, 1.06% Journal of Inorganic Biochemistry 1 publication, 1.06%
ChemInform	ChemInform, 1, 1.06% ChemInform 1 publication, 1.06%
ChemCatChem	ChemCatChem, 1, 1.06% ChemCatChem 1 publication, 1.06%
Chemical Society Reviews	Chemical Society Reviews, 1, 1.06% Chemical Society Reviews 1 publication, 1.06%
Modern Research in Catalysis	Modern Research in Catalysis, 1, 1.06% Modern Research in Catalysis 1 publication, 1.06%
Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya	Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya, 1, 1.06% Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya 1 publication, 1.06%
	2 4 6 8 10 12 14 16

Citations by publishers

	5 10 15 20 25 30
Elsevier	Elsevier, 29, 30.85% Elsevier 29 publications, 30.85%
American Chemical Society (ACS)	American Chemical Society (ACS), 19, 20.21% American Chemical Society (ACS) 19 publications, 20.21%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 18, 19.15% Royal Society of Chemistry (RSC) 18 publications, 19.15%
Wiley	Wiley, 17, 18.09% Wiley 17 publications, 18.09%
Springer Nature	Springer Nature, 4, 4.26% Springer Nature 4 publications, 4.26%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 2, 2.13% Multidisciplinary Digital Publishing Institute (MDPI) 2 publications, 2.13%
Korean Society of Industrial Engineering Chemistry	Korean Society of Industrial Engineering Chemistry, 1, 1.06% Korean Society of Industrial Engineering Chemistry 1 publication, 1.06%
Scientific Research Publishing	Scientific Research Publishing, 1, 1.06% Scientific Research Publishing 1 publication, 1.06%
Pleiades Publishing	Pleiades Publishing, 1, 1.06% Pleiades Publishing 1 publication, 1.06%
	5 10 15 20 25 30

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Omae I. Applications of five-membered ring products of cyclometalation reactions as anticancer agents // Coordination Chemistry Reviews. 2014. Vol. 280. pp. 84-95.

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Omae I. Applications of five-membered ring products of cyclometalation reactions as anticancer agents // Coordination Chemistry Reviews. 2014. Vol. 280. pp. 84-95.

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TY - JOUR

DO - 10.1016/j.ccr.2014.07.019

UR - https://doi.org/10.1016%2Fj.ccr.2014.07.019

TI - Applications of five-membered ring products of cyclometalation reactions as anticancer agents

T2 - Coordination Chemistry Reviews

AU - Omae, Iwao

PY - 2014

DA - 2014/11/01 00:00:00

PB - Elsevier

SP - 84-95

VL - 280

SN - 0010-8545

ER -

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@article{2014_Omae,

author = {Iwao Omae},

title = {Applications of five-membered ring products of cyclometalation reactions as anticancer agents},

journal = {Coordination Chemistry Reviews},

year = {2014},

volume = {280},

publisher = {Elsevier},

month = {nov},

url = {https://doi.org/10.1016%2Fj.ccr.2014.07.019},

pages = {84--95},

doi = {10.1016/j.ccr.2014.07.019}

}

Found error?

Publisher

Elsevier

Journal

Coordination Chemistry Reviews

Quartile SCImago

Quartile WOS

Impact factor

20.6

ISSN

00108545 (Print)