Coordination Chemistry Reviews, volume 309, pages 36-50

Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs

Publication typeJournal Article
Publication date2016-02-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor20.6
ISSN00108545
Materials Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Abstract
Water-soluble arene ruthenium complexes have been intensively studied as cytotoxic compounds for the last fifteen years, notably owing to the promising in vitro and in vivo evaluations of, respectively, RAPTA-C (η6-p-MeC6H4Pri)Ru(P-pta)Cl2 (pta = 1,3,5-triaza-7-phospha-tricyclo-[3.3.1.1]decane) from Dyson's laboratory, and the (η6-arene)Ru(en)Cl]+ (en = ethylenediamine, RAED) family of compounds from Sadler's laboratory. In this account we describe the discovery of thiolato-bridged dinuclear arene ruthenium complexes and highlight subsequent developments in the field, including their syntheses, structures, and the recent strategies for the design of thiolato-bridged dinuclear arene ruthenium bioconjugates.

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Furrer J., Süss-Fink G. Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs // Coordination Chemistry Reviews. 2016. Vol. 309. pp. 36-50.
GOST all authors (up to 50) Copy
Furrer J., Süss-Fink G. Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs // Coordination Chemistry Reviews. 2016. Vol. 309. pp. 36-50.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.ccr.2015.10.007
UR - https://doi.org/10.1016%2Fj.ccr.2015.10.007
TI - Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs
T2 - Coordination Chemistry Reviews
AU - Furrer, J.
AU - Süss-Fink, Georg
PY - 2016
DA - 2016/02/01 00:00:00
PB - Elsevier
SP - 36-50
VL - 309
SN - 0010-8545
ER -
BibTex
Cite this
BibTex Copy
@article{2016_Furrer,
author = {J. Furrer and Georg Süss-Fink},
title = {Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs},
journal = {Coordination Chemistry Reviews},
year = {2016},
volume = {309},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016%2Fj.ccr.2015.10.007},
pages = {36--50},
doi = {10.1016/j.ccr.2015.10.007}
}
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