Colloids and Surfaces B: Biointerfaces, volume 184, pages 110464

Enzymatic degradation of the polymer capsules with a hydrophobic core in the presence of Langmuir lipid monolayer as a model of the cellular membrane.

Publication typeJournal Article
Publication date2019-12-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5.8
ISSN09277765, 18734367
Physical and Theoretical Chemistry
General Medicine
Colloid and Surface Chemistry
Biotechnology
Surfaces and Interfaces
Abstract
Submicrocapsules were prepared from diethylaminoethyl dextran (DEAE-D), xanthan gum (XG) and bovine serum albumin (BSA) on oil cores by ultrasonic treatment. These capsules were modified with poly-L-lysine (PLL) via electrostatic adsorption. The behavior of the capsules was investigated at an air-water interface after their introduction into an aqueous subphase. The interaction of the capsules with 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) monolayer formed on the water surface (model cellular membrane) was studied both upon their introduction under the condensed monolayer and with the use of a dilute colloidal solution of the capsules as a subphase. Biodegradation of the proteinaceous capsules with subsequent oil-core release was demonstrated by influence of pronase. The Langmuir lipid monolayer was found to be a good model for investigation of drug release from the capsules in the presence of the cellular membrane.

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Mironov E. P. et al. Enzymatic degradation of the polymer capsules with a hydrophobic core in the presence of Langmuir lipid monolayer as a model of the cellular membrane. // Colloids and Surfaces B: Biointerfaces. 2019. Vol. 184. p. 110464.
GOST all authors (up to 50) Copy
Mironov E. P., Borodina T. N., Trushina D. B., Yurina D. G., Borodina T., Bukreeva T. V. Enzymatic degradation of the polymer capsules with a hydrophobic core in the presence of Langmuir lipid monolayer as a model of the cellular membrane. // Colloids and Surfaces B: Biointerfaces. 2019. Vol. 184. p. 110464.
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TY - JOUR
DO - 10.1016/j.colsurfb.2019.110464
UR - https://doi.org/10.1016%2Fj.colsurfb.2019.110464
TI - Enzymatic degradation of the polymer capsules with a hydrophobic core in the presence of Langmuir lipid monolayer as a model of the cellular membrane.
T2 - Colloids and Surfaces B: Biointerfaces
AU - Mironov, Evgenii P
AU - Borodina, Tatiana N
AU - Trushina, Daria B
AU - Yurina, Daria G
AU - Borodina, Tatiana
AU - Bukreeva, Tatiana V
PY - 2019
DA - 2019/12/01 00:00:00
PB - Elsevier
SP - 110464
VL - 184
SN - 0927-7765
SN - 1873-4367
ER -
BibTex
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BibTex Copy
@article{2019_Mironov,
author = {Evgenii P Mironov and Tatiana N Borodina and Daria B Trushina and Daria G Yurina and Tatiana Borodina and Tatiana V Bukreeva},
title = {Enzymatic degradation of the polymer capsules with a hydrophobic core in the presence of Langmuir lipid monolayer as a model of the cellular membrane.},
journal = {Colloids and Surfaces B: Biointerfaces},
year = {2019},
volume = {184},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016%2Fj.colsurfb.2019.110464},
pages = {110464},
doi = {10.1016/j.colsurfb.2019.110464}
}
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