European Polymer Journal, volume 133, pages 109722
Functionalized thermoresponsive microgels based on N-isopropylacrylamide: Energetics and mechanism of phase transitions
Manucha Walter
1
,
Burova Tatiana V
1
,
Grinberg Natalia V
1
,
Buyanovskaya Anastasiya G
1
,
Khokhlov Alexei R.
1, 2
,
Kozhunova Elena
2
,
Vyshivannaya Oxana V
1, 2
,
Nasimova Irina R
2
Publication type: Journal Article
Publication date: 2020-06-01
Journal:
European Polymer Journal
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 6
ISSN: 00143057
Materials Chemistry
Organic Chemistry
General Physics and Astronomy
Polymers and Plastics
Abstract
Abstract Nano- and micro-sized stimuli-responsive polymer containers capable of an effective controlled binding and release of ionic amphiphilic drugs are highly demanded in drug delivery. Thermoresponsive cross-linked microgels based on N-isopropylacrylamide (NIPAM) were synthesized by precipitation polymerization in aqueous media. The microgels were functionalized by the introduction of an ionic component (acrylic acid, AA, or vinyl sulfonate, VSA) either as a comonomer (NIPAM-co-AA and NIPAM-co-VSA microgels) or interpenetrating polymer network (PNIPAM-PAA microgel). The thermoresponsive behavior of the microgels was investigated by high-sensitivity differential scanning calorimetry. Thermodynamic parameters of the phase transitions (the transition temperature, enthalpy, and width) for the copolymer and interpenetrating microgels were determined. The copolymer microgels involving weak and strong ionogenic groups differ drastically by the transition energetics. This implies different types of their primary structures provided by either comonomer affinity or segregation in the reaction mixture under the polymerization conditions. The microgel functionalization via interpenetrating networks does not affect notably the transition temperature typical of the reference parent PNIPAM microgel but reduces the transition cooperativity. An analysis of the heat capacity profile of the microgel phase transition reveals some features of the mechanism of the thermoresponsivity in the microgels.
Citations by journals
|
1
2
3
|
|
|
European Polymer Journal
|
European Polymer Journal
3 publications, 20%
|
|
International Journal of Molecular Sciences
|
International Journal of Molecular Sciences
2 publications, 13.33%
|
|
Polymers
|
Polymers
2 publications, 13.33%
|
|
Macromolecules
|
Macromolecules
1 publication, 6.67%
|
|
International Journal of Biological Macromolecules
|
International Journal of Biological Macromolecules
1 publication, 6.67%
|
|
Journal of Physical Chemistry Letters
|
Journal of Physical Chemistry Letters
1 publication, 6.67%
|
|
Cellulose
|
Cellulose
1 publication, 6.67%
|
|
Polymer
|
Polymer
1 publication, 6.67%
|
|
Journal of Colloid and Interface Science
|
Journal of Colloid and Interface Science
1 publication, 6.67%
|
|
Pharmaceuticals
|
Pharmaceuticals
1 publication, 6.67%
|
|
Proceedings of universities. Applied chemistry and biotechnology
|
Proceedings of universities. Applied chemistry and biotechnology
1 publication, 6.67%
|
|
1
2
3
|
Citations by publishers
|
1
2
3
4
5
6
|
|
|
Elsevier
|
Elsevier
6 publications, 40%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
5 publications, 33.33%
|
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
2 publications, 13.33%
|
|
Springer Nature
|
Springer Nature
1 publication, 6.67%
|
|
Irkutsk National Research Technical University
|
Irkutsk National Research Technical University
1 publication, 6.67%
|
|
1
2
3
4
5
6
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2020,2021,2022,2023],"ids":[0,0,0,0],"codes":[0,0,0,0],"imageUrls":["","","",""],"datasets":[{"label":"Citations number","data":[4,3,5,3],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["26.67","20","33.33","20"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["European Polymer Journal","International Journal of Molecular Sciences","Polymers","Macromolecules","International Journal of Biological Macromolecules","Journal of Physical Chemistry Letters","Cellulose","Polymer","Journal of Colloid and Interface Science","Pharmaceuticals","Proceedings of universities. Applied chemistry and biotechnology"],"ids":[17319,14627,11204,20817,23035,21963,16441,19955,24202,1203,27984],"codes":[0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/bKpgtLRgEUS2yjwAv09mogh7UF6vC3G17WSy3dis_medium.webp"],"datasets":[{"label":"","data":[3,2,2,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[20,13.33,13.33,6.67,6.67,6.67,6.67,6.67,6.67,6.67,6.67],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","American Chemical Society (ACS)","Springer Nature","Irkutsk National Research Technical University"],"ids":[17,202,40,8,7440],"codes":[0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bKpgtLRgEUS2yjwAv09mogh7UF6vC3G17WSy3dis_medium.webp"],"datasets":[{"label":"","data":[6,5,2,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[40,33.33,13.33,6.67,6.67],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Manucha W. et al. Functionalized thermoresponsive microgels based on N-isopropylacrylamide: Energetics and mechanism of phase transitions // European Polymer Journal. 2020. Vol. 133. p. 109722.
GOST all authors (up to 50)
Copy
Manucha W., Burova T. V., Grinberg N. V., Buyanovskaya A. G., Khokhlov A. R., Kozhunova E., Vyshivannaya O. V., Nasimova I. R. Functionalized thermoresponsive microgels based on N-isopropylacrylamide: Energetics and mechanism of phase transitions // European Polymer Journal. 2020. Vol. 133. p. 109722.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.eurpolymj.2020.109722
UR - https://doi.org/10.1016%2Fj.eurpolymj.2020.109722
TI - Functionalized thermoresponsive microgels based on N-isopropylacrylamide: Energetics and mechanism of phase transitions
T2 - European Polymer Journal
AU - Manucha, Walter
AU - Burova, Tatiana V
AU - Grinberg, Natalia V
AU - Buyanovskaya, Anastasiya G
AU - Khokhlov, Alexei R.
AU - Kozhunova, Elena
AU - Vyshivannaya, Oxana V
AU - Nasimova, Irina R
PY - 2020
DA - 2020/06/01 00:00:00
PB - Elsevier
SP - 109722
VL - 133
SN - 0014-3057
ER -
Cite this
BibTex
Copy
@article{2020_Manucha,
author = {Walter Manucha and Tatiana V Burova and Natalia V Grinberg and Anastasiya G Buyanovskaya and Alexei R. Khokhlov and Elena Kozhunova and Oxana V Vyshivannaya and Irina R Nasimova},
title = {Functionalized thermoresponsive microgels based on N-isopropylacrylamide: Energetics and mechanism of phase transitions},
journal = {European Polymer Journal},
year = {2020},
volume = {133},
publisher = {Elsevier},
month = {jun},
url = {https://doi.org/10.1016%2Fj.eurpolymj.2020.109722},
pages = {109722},
doi = {10.1016/j.eurpolymj.2020.109722}
}
Profiles