Food Chemistry, volume 389, pages 133051

Nanopore-based aptasensor for label-free and sensitive vanillin determination in food samples

Elaguech Mohamed Amin ^{1, 2}

Bahri Mohamed ^{1, 2}

Djebbi Khouloud ^{1, 2}

Zhou Daming ^{1, 2}

Shi Bowen ^{1, 2}

Liang Liyuan ^{1, 2}

Komarova Natalia ³

Kuznetsov Alexander ^{3, 4}

TLILI CHAKER ^{1, 2}

Wang Deqiang ^{1, 2}

Hide authors affiliations Show authors affiliations: 4 affiliations

Chongqing School, University of Chinese Academy of Sciences (UCAS), Chongqing 400714, PR China |

Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, PR China |

SMC Technological Centre, Moscow 124498, Russia |

⁴

Institute of Nanotechnology of Microelectronics of the Russian Academy of Sciences, Moscow 119991, Russia |

Publication type: Journal Article

Publication date: 2022-09-01

Elsevier

Journal: Food Chemistry

Quartile SCImago

Quartile WOS

Impact factor: 8.8

ISSN: 03088146, 18737072

DOI: 10.1016/j.foodchem.2022.133051

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General Medicine

Analytical Chemistry

Food Science

Abstract

Dielectric breakdown technique was utlised to fabricate 5-6 nm nanopores for vanillin detection in various food samples. A highly selective aptamer (Van_74) with high binding affinity towards vanillin was used as capture probe. Under optimal conditions, aptamer/vanillin complex translocation induced deeper events than the bare aptamer. As a result, the proposed nanopore aptasensor exhibits a linear range from 0.5 to 5 nM (R2 = 0.972) and a low detection limit of 500 pM, which is significantly better than conventional platforms. Furthermore, our aptasensor showed excellent immunity against different interferons and was used to detect vanillin in different food samples. The food sample measurements were confirmed with an additional UV-Vis assay, the results of the two techniques were statistically evaluated and showed no statistically significant difference. Hence, this work represents a proof-of-concept involving the design and testing of aptamer/nanopore sensors for small molecules detection, which plays a critical role in food safety.

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Citations by journals

	1 2
Coordination Chemistry Reviews	Coordination Chemistry Reviews, 2, 18.18% Coordination Chemistry Reviews 2 publications, 18.18%
Sensors and Actuators, B: Chemical	Sensors and Actuators, B: Chemical, 2, 18.18% Sensors and Actuators, B: Chemical 2 publications, 18.18%
Nanomaterials	Nanomaterials, 1, 9.09% Nanomaterials 1 publication, 9.09%
Foods	Foods, 1, 9.09% Foods 1 publication, 9.09%
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 1, 9.09% Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 1 publication, 9.09%
Food Chemistry	Food Chemistry, 1, 9.09% Food Chemistry 1 publication, 9.09%
Analytical Letters	Analytical Letters, 1, 9.09% Analytical Letters 1 publication, 9.09%
Sensors & Diagnostics	Sensors & Diagnostics, 1, 9.09% Sensors & Diagnostics 1 publication, 9.09%
Microchemical Journal	Microchemical Journal, 1, 9.09% Microchemical Journal 1 publication, 9.09%
	1 2

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Elsevier	Elsevier, 7, 63.64% Elsevier 7 publications, 63.64%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 2, 18.18% Multidisciplinary Digital Publishing Institute (MDPI) 2 publications, 18.18%
Taylor & Francis	Taylor & Francis, 1, 9.09% Taylor & Francis 1 publication, 9.09%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 9.09% Royal Society of Chemistry (RSC) 1 publication, 9.09%
	1 2 3 4 5 6 7

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Elaguech M. A. et al. Nanopore-based aptasensor for label-free and sensitive vanillin determination in food samples // Food Chemistry. 2022. Vol. 389. p. 133051.

GOST all authors (up to 50) Copy

Elaguech M. A., Bahri M., Djebbi K., Zhou D., Shi B., Liang L., Komarova N., Kuznetsov A., TLILI C., Wang D. Nanopore-based aptasensor for label-free and sensitive vanillin determination in food samples // Food Chemistry. 2022. Vol. 389. p. 133051.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.foodchem.2022.133051

UR - https://doi.org/10.1016%2Fj.foodchem.2022.133051

TI - Nanopore-based aptasensor for label-free and sensitive vanillin determination in food samples

T2 - Food Chemistry

AU - Elaguech, Mohamed Amin

AU - Bahri, Mohamed

AU - Djebbi, Khouloud

AU - Zhou, Daming

AU - Shi, Bowen

AU - Liang, Liyuan

AU - Komarova, Natalia

AU - Kuznetsov, Alexander

AU - TLILI, CHAKER

AU - Wang, Deqiang

PY - 2022

DA - 2022/09/01 00:00:00

PB - Elsevier

SP - 133051

VL - 389

SN - 0308-8146

SN - 1873-7072

ER -

BibTex

Cite this

BibTex Copy

@article{2022_Elaguech,

author = {Mohamed Amin Elaguech and Mohamed Bahri and Khouloud Djebbi and Daming Zhou and Bowen Shi and Liyuan Liang and Natalia Komarova and Alexander Kuznetsov and CHAKER TLILI and Deqiang Wang},

title = {Nanopore-based aptasensor for label-free and sensitive vanillin determination in food samples},

journal = {Food Chemistry},

year = {2022},

volume = {389},

publisher = {Elsevier},

month = {sep},

url = {https://doi.org/10.1016%2Fj.foodchem.2022.133051},

pages = {133051},

doi = {10.1016/j.foodchem.2022.133051}

}

Found error?

Publisher

Elsevier

Journal

Food Chemistry

Quartile SCImago

Quartile WOS

Impact factor

8.8

ISSN

03088146 (Print)
18737072 (Electronic)

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Нанопоровые датчики с искусственными олигонуклеотидами помогли обнаружить ванилин