Journal of Fluorine Chemistry, volume 163, pages 34-37

Synthesis of 1-aryl-4-tosyl-5-(trifluoromethyl)-1H-imidazoles

Publication typeJournal Article
Publication date2014-07-01
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor1.9
ISSN00221139
Organic Chemistry
Biochemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Environmental Chemistry
Abstract
A new synthetic protocol for the synthesis of 1,4,5-trisubstituted imidazoles containing trifluoromethyl group has been developed using van Leusen reaction, which incorporates two-component condensation reaction trifluoroacetimidoyl chlorides with tosylmethylisocyanide. This protocol provides a novel and improved method for obtaining trifluoromethyl containing 1,4,5-trisubstituted imidazoles in good yields.

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GOST Copy
Bunev A. S. et al. Synthesis of 1-aryl-4-tosyl-5-(trifluoromethyl)-1H-imidazoles // Journal of Fluorine Chemistry. 2014. Vol. 163. pp. 34-37.
GOST all authors (up to 50) Copy
Bunev A. S., Vasiliev M. A., Statsyuk V. E., Ostapenko G. I., Peregudov A. S. Synthesis of 1-aryl-4-tosyl-5-(trifluoromethyl)-1H-imidazoles // Journal of Fluorine Chemistry. 2014. Vol. 163. pp. 34-37.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.jfluchem.2014.04.013
UR - https://doi.org/10.1016%2Fj.jfluchem.2014.04.013
TI - Synthesis of 1-aryl-4-tosyl-5-(trifluoromethyl)-1H-imidazoles
T2 - Journal of Fluorine Chemistry
AU - Vasiliev, Maksim A.
AU - Statsyuk, Vladimir E.
AU - Ostapenko, Gennady I.
AU - Bunev, Alexander S.
AU - Peregudov, A. S.
PY - 2014
DA - 2014/07/01 00:00:00
PB - Elsevier
SP - 34-37
VL - 163
SN - 0022-1139
ER -
BibTex
Cite this
BibTex Copy
@article{2014_Bunev,
author = {Maksim A. Vasiliev and Vladimir E. Statsyuk and Gennady I. Ostapenko and Alexander S. Bunev and A. S. Peregudov},
title = {Synthesis of 1-aryl-4-tosyl-5-(trifluoromethyl)-1H-imidazoles},
journal = {Journal of Fluorine Chemistry},
year = {2014},
volume = {163},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016%2Fj.jfluchem.2014.04.013},
pages = {34--37},
doi = {10.1016/j.jfluchem.2014.04.013}
}
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