Journal of Magnetism and Magnetic Materials, volume 475, pages 108-114

Human serum albumin as an effective coating for hydrophobic photosensitizes immobilization on magnetic nanoparticles

Abakumov Maxim
Chekhonin Vladimir
Kireev Igor
Semkina Alevtina 2
Majouga Alexander
Vlasova Kseniya
Grin Mikhail 1
Smirnov A.V. 1
Vedenyapina Daria 1
Kireev I. 5
Чехонин В. П. 6
Publication typeJournal Article
Publication date2019-04-01
Quartile SCImago
Q2
Quartile WOS
Q3
Impact factor2.7
ISSN03048853
Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Abstract
Abstract Magnetic nanoparticles are widely used in various fields of biomedicine. They can combine both therapy and diagnostics modalities thus opening many opportunities for their application. In our work, we have evaluated their ability to work as contrast agents for magnetic resonance imagining and drug delivery systems for photosensitizers. We have shown that after formation of human serum albumin retains ability to bind photosensitizers and they do not lose their optical properties. To obtain stable water solution suitable for long term storage we have additionally modified human serum albumin with polyethylene glycol. It was shown that such modification allows to increase overall stability over time.

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Ostroverkhov P. et al. Human serum albumin as an effective coating for hydrophobic photosensitizes immobilization on magnetic nanoparticles // Journal of Magnetism and Magnetic Materials. 2019. Vol. 475. pp. 108-114.
GOST all authors (up to 50) Copy
Semkina A., Nikitin A., Majouga A., Grin M., Vlasova K., Smirnov A., Abakumov M., Chekhonin V., Kireev I., Vedenyapina M. D., Ostroverkhov P., Nikitin A. A., Smirnov A., Vedenyapina D., Vlasova K. Y., Kireev I., Чехонин В. П., Majouga A. G., Abakumov M. A. Human serum albumin as an effective coating for hydrophobic photosensitizes immobilization on magnetic nanoparticles // Journal of Magnetism and Magnetic Materials. 2019. Vol. 475. pp. 108-114.
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RIS Copy
TY - JOUR
DO - 10.1016/j.jmmm.2018.10.135
UR - https://doi.org/10.1016%2Fj.jmmm.2018.10.135
TI - Human serum albumin as an effective coating for hydrophobic photosensitizes immobilization on magnetic nanoparticles
T2 - Journal of Magnetism and Magnetic Materials
AU - Ostroverkhov, Petr
AU - Semkina, Alevtina
AU - Vedenyapina, Marina D.
AU - Kireev, Igor
AU - Chekhonin, Vladimir
AU - Abakumov, Maxim
AU - Smirnov, Alexander
AU - Vlasova, Kseniya
AU - Grin, Mikhail
AU - Majouga, Alexander
AU - Nikitin, Aleksey
AU - Nikitin, Aleksey A
AU - Smirnov, A.V.
AU - Vedenyapina, Daria
AU - Vlasova, Kseniya Yu.
AU - Kireev, I.
AU - Чехонин, В. П.
AU - Majouga, Alexander G.
AU - Abakumov, Maxim A.
PY - 2019
DA - 2019/04/01 00:00:00
PB - Elsevier
SP - 108-114
VL - 475
SN - 0304-8853
ER -
BibTex
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BibTex Copy
@article{2019_Ostroverkhov,
author = {Petr Ostroverkhov and Alevtina Semkina and Marina D. Vedenyapina and Igor Kireev and Vladimir Chekhonin and Maxim Abakumov and Alexander Smirnov and Kseniya Vlasova and Mikhail Grin and Alexander Majouga and Aleksey Nikitin and Aleksey A Nikitin and A.V. Smirnov and Daria Vedenyapina and Kseniya Yu. Vlasova and I. Kireev and В. П. Чехонин and Alexander G. Majouga and Maxim A. Abakumov},
title = {Human serum albumin as an effective coating for hydrophobic photosensitizes immobilization on magnetic nanoparticles},
journal = {Journal of Magnetism and Magnetic Materials},
year = {2019},
volume = {475},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016%2Fj.jmmm.2018.10.135},
pages = {108--114},
doi = {10.1016/j.jmmm.2018.10.135}
}
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