Nanomedicine: Nanotechnology, Biology, and Medicine, volume 25, pages 102171

Temperature-controlled magnetic nanoparticles hyperthermia inhibits primary tumor growth and metastases dissemination

Garanina A. S. 1, 2
Naumenko Victor 3, 4
Myrovali E 7
Petukhova Anna Y 8
Klimyuk Svetlana V 8
Ilyasov Artem R 8
Angelakeris Mavroeidis 7
Wiedwald U. 4, 10
Majouga Alexander G. 2, 4, 11
Publication typeJournal Article
Publication date2020-04-01
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor5.4
ISSN15499634, 15499642
Medicine (miscellaneous)
Pharmaceutical Science
Molecular Medicine
General Materials Science
Bioengineering
Biomedical Engineering
Abstract
Magnetic hyperthermia (MHT) is a promising approach for cancer therapy. However, a systematic MHT characterization as function of temperature on the therapeutic efficiency is barely analyzed. Here, we first perform comparative temperature-dependent analysis of the cobalt ferrite nanoparticles-mediated MHT effectiveness in two murine tumors models - breast (4T1) and colon (CT26) cancer in vitro and in vivo. The overall MHT killing capacity in vitro increased with the temperature and CT26 cells were more sensitive than 4T1 when heated to 43 °C. Well in line with the in vitro data, such heating cured non-metastatic CT26 tumors in vivo, while only inhibiting metastatic 4T1 tumor growth without improving the overall survival. High-temperature MHT (>47 °C) resulted in complete 4T1 primary tumor clearance, 25-40% long-term survival rates, and, importantly, more effective prevention of metastasis comparing to surgical extraction. Thus, the specific MHT temperature must be defined for each tumor individually to ensure a successful antitumor therapy.

Citations by journals

1
2
3
4
Nanomaterials
Nanomaterials, 4, 7.84%
Nanomaterials
4 publications, 7.84%
Pharmaceutics
Pharmaceutics, 2, 3.92%
Pharmaceutics
2 publications, 3.92%
Chemical Communications
Chemical Communications, 2, 3.92%
Chemical Communications
2 publications, 3.92%
Pharmaceuticals
Pharmaceuticals, 2, 3.92%
Pharmaceuticals
2 publications, 3.92%
Journal of Physical Chemistry Letters
Journal of Physical Chemistry Letters, 1, 1.96%
Journal of Physical Chemistry Letters
1 publication, 1.96%
Bulletin of the Russian Academy of Sciences: Physics
Bulletin of the Russian Academy of Sciences: Physics, 1, 1.96%
Bulletin of the Russian Academy of Sciences: Physics
1 publication, 1.96%
Journal of Biomedical Nanotechnology
Journal of Biomedical Nanotechnology, 1, 1.96%
Journal of Biomedical Nanotechnology
1 publication, 1.96%
AIP Advances
AIP Advances, 1, 1.96%
AIP Advances
1 publication, 1.96%
Molecules
Molecules, 1, 1.96%
Molecules
1 publication, 1.96%
Polymers
Polymers, 1, 1.96%
Polymers
1 publication, 1.96%
Cancers
Cancers, 1, 1.96%
Cancers
1 publication, 1.96%
Materials
Materials, 1, 1.96%
Materials
1 publication, 1.96%
Life
Life, 1, 1.96%
Life
1 publication, 1.96%
Membranes
Membranes, 1, 1.96%
Membranes
1 publication, 1.96%
Journal of Materials Science
Journal of Materials Science, 1, 1.96%
Journal of Materials Science
1 publication, 1.96%
Journal of Radioanalytical and Nuclear Chemistry
Journal of Radioanalytical and Nuclear Chemistry, 1, 1.96%
Journal of Radioanalytical and Nuclear Chemistry
1 publication, 1.96%
Scientific Reports
Scientific Reports, 1, 1.96%
Scientific Reports
1 publication, 1.96%
Journal of Materials Research
Journal of Materials Research, 1, 1.96%
Journal of Materials Research
1 publication, 1.96%
Materials Today: Proceedings
Materials Today: Proceedings, 1, 1.96%
Materials Today: Proceedings
1 publication, 1.96%
Materials and Design
Materials and Design, 1, 1.96%
Materials and Design
1 publication, 1.96%
Materials Science in Semiconductor Processing
Materials Science in Semiconductor Processing, 1, 1.96%
Materials Science in Semiconductor Processing
1 publication, 1.96%
Journal of Magnetism and Magnetic Materials
Journal of Magnetism and Magnetic Materials, 1, 1.96%
Journal of Magnetism and Magnetic Materials
1 publication, 1.96%
Ceramics International
Ceramics International, 1, 1.96%
Ceramics International
1 publication, 1.96%
Nonlinear Dynamics
Nonlinear Dynamics, 1, 1.96%
Nonlinear Dynamics
1 publication, 1.96%
Ultrasound in Medicine and Biology
Ultrasound in Medicine and Biology, 1, 1.96%
Ultrasound in Medicine and Biology
1 publication, 1.96%
Biocybernetics and Biomedical Engineering
Biocybernetics and Biomedical Engineering, 1, 1.96%
Biocybernetics and Biomedical Engineering
1 publication, 1.96%
Biomedicine and Pharmacotherapy
Biomedicine and Pharmacotherapy, 1, 1.96%
Biomedicine and Pharmacotherapy
1 publication, 1.96%
IEEJ Transactions on Electrical and Electronic Engineering
IEEJ Transactions on Electrical and Electronic Engineering, 1, 1.96%
IEEJ Transactions on Electrical and Electronic Engineering
1 publication, 1.96%
Advanced healthcare materials
Advanced healthcare materials, 1, 1.96%
Advanced healthcare materials
1 publication, 1.96%
1
2
3
4

Citations by publishers

2
4
6
8
10
12
14
16
Multidisciplinary Digital Publishing Institute (MDPI)
Multidisciplinary Digital Publishing Institute (MDPI), 16, 31.37%
Multidisciplinary Digital Publishing Institute (MDPI)
16 publications, 31.37%
Elsevier
Elsevier, 8, 15.69%
Elsevier
8 publications, 15.69%
Springer Nature
Springer Nature, 5, 9.8%
Springer Nature
5 publications, 9.8%
Royal Society of Chemistry (RSC)
Royal Society of Chemistry (RSC), 5, 9.8%
Royal Society of Chemistry (RSC)
5 publications, 9.8%
Wiley
Wiley, 4, 7.84%
Wiley
4 publications, 7.84%
American Chemical Society (ACS)
American Chemical Society (ACS), 2, 3.92%
American Chemical Society (ACS)
2 publications, 3.92%
Pleiades Publishing
Pleiades Publishing, 2, 3.92%
Pleiades Publishing
2 publications, 3.92%
American Scientific Publishers
American Scientific Publishers, 1, 1.96%
American Scientific Publishers
1 publication, 1.96%
American Institute of Physics (AIP)
American Institute of Physics (AIP), 1, 1.96%
American Institute of Physics (AIP)
1 publication, 1.96%
Cambridge University Press
Cambridge University Press, 1, 1.96%
Cambridge University Press
1 publication, 1.96%
Taylor & Francis
Taylor & Francis, 1, 1.96%
Taylor & Francis
1 publication, 1.96%
Hindawi Limited
Hindawi Limited, 1, 1.96%
Hindawi Limited
1 publication, 1.96%
Frontiers Media S.A.
Frontiers Media S.A., 1, 1.96%
Frontiers Media S.A.
1 publication, 1.96%
2
4
6
8
10
12
14
16
  • We do not take into account publications that without a DOI.
  • Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
  • Statistics recalculated weekly.
Metrics
Share
Cite this
GOST |
Cite this
GOST Copy
Garanina A. S. et al. Temperature-controlled magnetic nanoparticles hyperthermia inhibits primary tumor growth and metastases dissemination // Nanomedicine: Nanotechnology, Biology, and Medicine. 2020. Vol. 25. p. 102171.
GOST all authors (up to 50) Copy
Garanina A. S., Naumenko V., Nikitin A. A., Myrovali E., Petukhova A. Y., Klimyuk S. V., Nalench Y. A., Ilyasov A. R., Vodopyanov S. S., Erofeev A. V., Gorelkin P., Angelakeris M., Savchenko A. G., Wiedwald U., Majouga A. G., Abakumov M. A. Temperature-controlled magnetic nanoparticles hyperthermia inhibits primary tumor growth and metastases dissemination // Nanomedicine: Nanotechnology, Biology, and Medicine. 2020. Vol. 25. p. 102171.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.nano.2020.102171
UR - https://doi.org/10.1016%2Fj.nano.2020.102171
TI - Temperature-controlled magnetic nanoparticles hyperthermia inhibits primary tumor growth and metastases dissemination
T2 - Nanomedicine: Nanotechnology, Biology, and Medicine
AU - Garanina, A. S.
AU - Naumenko, Victor
AU - Nikitin, Alexey A.
AU - Myrovali, E
AU - Petukhova, Anna Y
AU - Klimyuk, Svetlana V
AU - Nalench, Yulia A
AU - Ilyasov, Artem R
AU - Vodopyanov, Stepan S
AU - Erofeev, Alexander V.
AU - Gorelkin, Peter
AU - Angelakeris, Mavroeidis
AU - Savchenko, Alexander G.
AU - Wiedwald, U.
AU - Majouga, Alexander G.
AU - Abakumov, Maxim A.
PY - 2020
DA - 2020/04/01 00:00:00
PB - Elsevier
SP - 102171
VL - 25
SN - 1549-9634
SN - 1549-9642
ER -
BibTex
Cite this
BibTex Copy
@article{2020_Garanina
author = {A. S. Garanina and Victor Naumenko and Alexey A. Nikitin and E Myrovali and Anna Y Petukhova and Svetlana V Klimyuk and Yulia A Nalench and Artem R Ilyasov and Stepan S Vodopyanov and Alexander V. Erofeev and Peter Gorelkin and Mavroeidis Angelakeris and Alexander G. Savchenko and U. Wiedwald and Alexander G. Majouga and Maxim A. Abakumov},
title = {Temperature-controlled magnetic nanoparticles hyperthermia inhibits primary tumor growth and metastases dissemination},
journal = {Nanomedicine: Nanotechnology, Biology, and Medicine},
year = {2020},
volume = {25},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016%2Fj.nano.2020.102171},
pages = {102171},
doi = {10.1016/j.nano.2020.102171}
}
Found error?