Pancreatology, volume 18, issue 8, pages 862-867

Dilemma of elevated CA 19-9 in biliary pathology.

Tsen Adrianne 1
Barbara Mary 2
Rosenkranz Laura 3
1
 
University of Texas Health Science Center at San Antonio, 5623 Hamilton Wolfe, #712, San Antonio, TX 78240, USA
2
 
Department of Internal Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
3
 
Department of Gastroenterology and Advanced Therapeutic Endoscopy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
Publication typeJournal Article
Publication date2018-12-01
Journal: Pancreatology
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor3.6
ISSN14243903, 14243911
Endocrinology, Diabetes and Metabolism
Gastroenterology
Hepatology
Abstract
Carbohydrate antigen 19-9 (CA 19-9) is a tumor marker which has been extensively evaluated and widely utilized primarily in diagnosing and prognosticating pancreaticobiliary malignancies. Levels may be significantly influenced and elevated in cases of benign biliary conditions however, especially in obstructive jaundice, thereby posing difficulty in distinguishing between benign and malignant cholestasis. A myriad of studies have focused on elucidating proper use and interpretation of CA 19-9 in pancreatic cancer as well as in the setting of cholestasis. These studies have demonstrated that many factors influence CA 19-9 values and various methods for interpreting CA 19-9 in obstructive jaundice have been proposed. With improvements in diagnostic imaging, advancements in endoscopic modalities, and likelihood that management will not change based on the results of the test, clinicians should be cautious when ordering CA 19-9 and consider the reasons for measuring the tumor marker.

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Tsen A., Barbara M., Rosenkranz L. Dilemma of elevated CA 19-9 in biliary pathology. // Pancreatology. 2018. Vol. 18. No. 8. pp. 862-867.
GOST all authors (up to 50) Copy
Tsen A., Barbara M., Rosenkranz L. Dilemma of elevated CA 19-9 in biliary pathology. // Pancreatology. 2018. Vol. 18. No. 8. pp. 862-867.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.pan.2018.09.004
UR - https://doi.org/10.1016%2Fj.pan.2018.09.004
TI - Dilemma of elevated CA 19-9 in biliary pathology.
T2 - Pancreatology
AU - Tsen, Adrianne
AU - Barbara, Mary
AU - Rosenkranz, Laura
PY - 2018
DA - 2018/12/01 00:00:00
PB - Elsevier
SP - 862-867
IS - 8
VL - 18
SN - 1424-3903
SN - 1424-3911
ER -
BibTex |
Cite this
BibTex Copy
@article{2018_Tsen,
author = {Adrianne Tsen and Mary Barbara and Laura Rosenkranz},
title = {Dilemma of elevated CA 19-9 in biliary pathology.},
journal = {Pancreatology},
year = {2018},
volume = {18},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016%2Fj.pan.2018.09.004},
number = {8},
pages = {862--867},
doi = {10.1016/j.pan.2018.09.004}
}
MLA
Cite this
MLA Copy
Tsen, Adrianne, et al. “Dilemma of elevated CA 19-9 in biliary pathology..” Pancreatology, vol. 18, no. 8, Dec. 2018, pp. 862-867. https://doi.org/10.1016%2Fj.pan.2018.09.004.
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