Trends in Genetics, volume 31, issue 8, pages 445-453

Metabolic regulation in model ascomycetes – adjusting similar genomes to different lifestyles

Whiteway Malcolm 1
Tebung Walters A 1
Choudhury Baharul I 1
Rodríguez-Ortiz Roberto 1
1
 
Biology Department, Concordia University, 7141 Sherbrooke Street West, Montreal, Quebec H4B 1R6, Canada.
Publication typeJournal Article
Publication date2015-08-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor11.4
ISSN01689525, 13624555
Genetics
Abstract
The related yeasts Saccharomyces cerevisiae and Candida albicans have similar genomes but very different lifestyles. These fungi have modified transcriptional and post-translational regulatory processes to adapt their similar genomes to the distinct biological requirements of the two yeasts. We review recent findings comparing the differences between these species, highlighting how they have achieved specialized metabolic capacities tailored to their lifestyles despite sharing similar genomes. Studying this transcriptional and post-transcriptional rewiring may improve our ability to interpret phenotype from genotype.

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GOST |
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GOST Copy
Whiteway M. et al. Metabolic regulation in model ascomycetes – adjusting similar genomes to different lifestyles // Trends in Genetics. 2015. Vol. 31. No. 8. pp. 445-453.
GOST all authors (up to 50) Copy
Whiteway M., Tebung W. A., Choudhury B. I., Rodríguez-Ortiz R. Metabolic regulation in model ascomycetes – adjusting similar genomes to different lifestyles // Trends in Genetics. 2015. Vol. 31. No. 8. pp. 445-453.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.tig.2015.05.002
UR - https://doi.org/10.1016%2Fj.tig.2015.05.002
TI - Metabolic regulation in model ascomycetes – adjusting similar genomes to different lifestyles
T2 - Trends in Genetics
AU - Whiteway, Malcolm
AU - Tebung, Walters A
AU - Choudhury, Baharul I
AU - Rodríguez-Ortiz, Roberto
PY - 2015
DA - 2015/08/01 00:00:00
PB - Elsevier
SP - 445-453
IS - 8
VL - 31
SN - 0168-9525
SN - 1362-4555
ER -
BibTex |
Cite this
BibTex Copy
@article{2015_Whiteway,
author = {Malcolm Whiteway and Walters A Tebung and Baharul I Choudhury and Roberto Rodríguez-Ortiz},
title = {Metabolic regulation in model ascomycetes – adjusting similar genomes to different lifestyles},
journal = {Trends in Genetics},
year = {2015},
volume = {31},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016%2Fj.tig.2015.05.002},
number = {8},
pages = {445--453},
doi = {10.1016/j.tig.2015.05.002}
}
MLA
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MLA Copy
Whiteway, Malcolm, et al. “Metabolic regulation in model ascomycetes – adjusting similar genomes to different lifestyles.” Trends in Genetics, vol. 31, no. 8, Aug. 2015, pp. 445-453. https://doi.org/10.1016%2Fj.tig.2015.05.002.
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