Frontiers in Neuroendocrinology, volume 67, pages 101014

The critical impact of sex on preclinical alcohol research – Insights from zebrafish

Abreu Murilo S. 1
, 
Parker Matthew O. 2
, 
Kalueff Allan V. 3, 4, 5, 6, 7, 8, 9, 10
1
 
2
 
School of Pharmacy and Biomedical Science, University of Portsmouth, UK | 
3
 
4
 
5
 
6
 
7
 
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Publication type: Journal Article
Publication date: 2022-10-01
Quartile SCImago
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Impact factor: 7.4
ISSN: 00913022, 10956808
Endocrine and Autonomic Systems
Abstract
• Sex is an important biological variable in translational neuroscience research. • There are overt sex differences in clinical and preclinical alcohol research. • The use of zebrafish ( Danio rerio ) in pre-clinical alcohol research rapidly grows. • Here, we discuss zebrafish models to study sex differences in alcohol brain action. Sex is an important biological variable that is widely recognized in studies of alcohol-related effects. Complementing clinical and preclinical rodent research, the zebrafish ( Danio rerio ) is the second most used laboratory species, and a powerful model organism in biomedicine. Like clinical and rodent models, zebrafish demonstrate overt sex differences in alcohol-related responses. Collectively, this evidence shows that the zebrafish becomes a sensitive model species to further probe in-depth sex differences commonly reported in alcohol research.
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Abreu M. S. et al. The critical impact of sex on preclinical alcohol research – Insights from zebrafish // Frontiers in Neuroendocrinology. 2022. Vol. 67. p. 101014.
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Abreu M. S., Parker M. O., Kalueff A. V. The critical impact of sex on preclinical alcohol research – Insights from zebrafish // Frontiers in Neuroendocrinology. 2022. Vol. 67. p. 101014.
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TY - JOUR
DO - 10.1016/j.yfrne.2022.101014
UR - https://doi.org/10.1016%2Fj.yfrne.2022.101014
TI - The critical impact of sex on preclinical alcohol research – Insights from zebrafish
T2 - Frontiers in Neuroendocrinology
AU - Abreu, Murilo S.
AU - Parker, Matthew O.
AU - Kalueff, Allan V.
PY - 2022
DA - 2022/10/01 00:00:00
PB - Elsevier
SP - 101014
VL - 67
SN - 0091-3022
SN - 1095-6808
ER -
BibTex
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BibTex Copy
@article{2022_Abreu,
author = {Murilo S. Abreu and Matthew O. Parker and Allan V. Kalueff},
title = {The critical impact of sex on preclinical alcohol research – Insights from zebrafish},
journal = {Frontiers in Neuroendocrinology},
year = {2022},
volume = {67},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016%2Fj.yfrne.2022.101014},
pages = {101014},
doi = {10.1016/j.yfrne.2022.101014}
}
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