N-Propargylic β-Enaminones: Common Intermediates for the Synthesis of Polysubstituted Pyrroles and Pyridines
Publication type: Journal Article
Publication date: 2008-05-29
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
18507386
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
N-Propargylic β-enaminones have been used as common intermediates for the synthesis of polysubstituted pyrroles and pyridines. Best results have been obtained using DMSO as solvent. In the presence of Cs2CO3 N-propargylic β-enaminones are cyclized to pyrroles in good to high yields, whereas omitting bases and using CuBr leads to the selective formation of pyridines.
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214
Total citations:
214
Citations from 2024:
13
(6%)
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GOST
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Cacchi S., Fabrizi G., Filisti E. N-Propargylic β-Enaminones: Common Intermediates for the Synthesis of Polysubstituted Pyrroles and Pyridines // Organic Letters. 2008. Vol. 10. No. 13. pp. 2629-2632.
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Cacchi S., Fabrizi G., Filisti E. N-Propargylic β-Enaminones: Common Intermediates for the Synthesis of Polysubstituted Pyrroles and Pyridines // Organic Letters. 2008. Vol. 10. No. 13. pp. 2629-2632.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/ol800518j
UR - https://doi.org/10.1021/ol800518j
TI - N-Propargylic β-Enaminones: Common Intermediates for the Synthesis of Polysubstituted Pyrroles and Pyridines
T2 - Organic Letters
AU - Cacchi, Sandro
AU - Fabrizi, Giancarlo
AU - Filisti, Eleonora
PY - 2008
DA - 2008/05/29
PB - American Chemical Society (ACS)
SP - 2629-2632
IS - 13
VL - 10
PMID - 18507386
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2008_Cacchi,
author = {Sandro Cacchi and Giancarlo Fabrizi and Eleonora Filisti},
title = {N-Propargylic β-Enaminones: Common Intermediates for the Synthesis of Polysubstituted Pyrroles and Pyridines},
journal = {Organic Letters},
year = {2008},
volume = {10},
publisher = {American Chemical Society (ACS)},
month = {may},
url = {https://doi.org/10.1021/ol800518j},
number = {13},
pages = {2629--2632},
doi = {10.1021/ol800518j}
}
Cite this
MLA
Copy
Cacchi, Sandro, et al. “N-Propargylic β-Enaminones: Common Intermediates for the Synthesis of Polysubstituted Pyrroles and Pyridines.” Organic Letters, vol. 10, no. 13, May. 2008, pp. 2629-2632. https://doi.org/10.1021/ol800518j.