Open Access
Open access
ACS Nano, volume 3, issue 9, pages 2451-2460

Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition

Wang Hao 1, 2
Yang Ronghua 1
Yang Liu 3
1
 
Biomedical Engineering Center, State Key Lab of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China
3
 
Center for Research at the Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center and UF Genetics Institute, University of Florida, Gainesville, Florida 32611-7200
Publication typeJournal Article
Publication date2009-08-06
Journal: ACS Nano
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor17.1
ISSN19360851, 1936086X
PubMed ID:  19658387
General Physics and Astronomy
General Materials Science
General Engineering
Abstract
Nucleic acids, whether designed or selected in vitro, play important roles in biosensing, medical diagnostics, and therapy. Specifically, the conjugation of functional nucleic acid based probe molecules and nanomaterials has resulted in an unprecedented improvement in the field of molecular recognition. With their unique physical and chemical properties, nanomaterials facilitate the sensing process and amplify the signal of recognition events. Thus, the coupling of nucleic acids with various nanomaterials opens up a promising future for molecular recognition. The literature offers a broad spectrum of recent advances in biosensing by employing different nanoplatforms with designed nucleic acids, especially gold nanoparticles, carbon nanotubes, silica nanoparticles, and quantum dots. The advantages of these novel combinations are discussed from the perspective of molecular recognition in chemistry, biology, and medicine, along with the problems confronting future applications.

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GOST Copy
Wang H. et al. Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition // ACS Nano. 2009. Vol. 3. No. 9. pp. 2451-2460.
GOST all authors (up to 50) Copy
Wang H., Yang R., Yang L., Tan W. Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition // ACS Nano. 2009. Vol. 3. No. 9. pp. 2451-2460.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/nn9006303
UR - https://doi.org/10.1021%2Fnn9006303
TI - Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition
T2 - ACS Nano
AU - Wang, Hao
AU - Yang, Ronghua
AU - Yang, Liu
AU - Tan, Weihong
PY - 2009
DA - 2009/08/06 00:00:00
PB - American Chemical Society (ACS)
SP - 2451-2460
IS - 9
VL - 3
PMID - 19658387
SN - 1936-0851
SN - 1936-086X
ER -
BibTex |
Cite this
BibTex Copy
@article{2009_Wang,
author = {Hao Wang and Ronghua Yang and Liu Yang and Weihong Tan},
title = {Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition},
journal = {ACS Nano},
year = {2009},
volume = {3},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021%2Fnn9006303},
number = {9},
pages = {2451--2460},
doi = {10.1021/nn9006303}
}
MLA
Cite this
MLA Copy
Wang, Hao, et al. “Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition.” ACS Nano, vol. 3, no. 9, Aug. 2009, pp. 2451-2460. https://doi.org/10.1021%2Fnn9006303.
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