Nature, volume 362, issue 6422, pages 709-715
Instability and decay of the primary structure of DNA
1
Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms. Hertfordshire, UK
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Publication type: Journal Article
Publication date: 1993-04-01
DOI:
10.1038/362709a0
Multidisciplinary
Abstract
Although DNA is the carrier of genetic information, it has limited chemical stability. Hydrolysis, oxidation and nonenzymatic methylation of DNA occur at significant ratesin vivo, and are counteracted by specific DNA repair processes. The spontaneous decay of DNA is likely to be a major factor in mutagenesis, carcinogenesis and ageing, and also sets limits for the recovery of DNA fragments from fossils.
Citations by journals
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Journal of Biological Chemistry
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Journal of Biological Chemistry
155 publications, 3.8%
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DNA Repair
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DNA Repair
139 publications, 3.4%
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Nucleic Acids Research
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Nucleic Acids Research
132 publications, 3.23%
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PLoS ONE
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PLoS ONE
77 publications, 1.89%
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
74 publications, 1.81%
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International Journal of Molecular Sciences
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International Journal of Molecular Sciences
49 publications, 1.2%
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Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
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Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
47 publications, 1.15%
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Biochemistry
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Biochemistry
34 publications, 0.83%
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Nature
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Nature
33 publications, 0.81%
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Mutation Research/DNA Repair
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Mutation Research/DNA Repair
31 publications, 0.76%
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Journal of Molecular Biology
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Journal of Molecular Biology
31 publications, 0.76%
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Scientific Reports
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Scientific Reports
31 publications, 0.76%
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Journal of Bacteriology
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Journal of Bacteriology
28 publications, 0.69%
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Journal of the American Chemical Society
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Journal of the American Chemical Society
27 publications, 0.66%
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Journal of Archaeological Science
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Journal of Archaeological Science
27 publications, 0.66%
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Science
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Science
27 publications, 0.66%
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Forensic Science International: Genetics
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Forensic Science International: Genetics
26 publications, 0.64%
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Molecular Cell
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Molecular Cell
24 publications, 0.59%
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Genes
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Genes
24 publications, 0.59%
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Mechanisms of Ageing and Development
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Mechanisms of Ageing and Development
23 publications, 0.56%
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Molecular and Cellular Biology
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Molecular and Cellular Biology
22 publications, 0.54%
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Methods in Molecular Biology
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Methods in Molecular Biology
20 publications, 0.49%
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Nature Communications
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Nature Communications
20 publications, 0.49%
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BioEssays
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BioEssays
20 publications, 0.49%
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Molecular Ecology
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Molecular Ecology
18 publications, 0.44%
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Chemical Research in Toxicology
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Chemical Research in Toxicology
18 publications, 0.44%
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Oncogene
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Oncogene
17 publications, 0.42%
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Environmental and Molecular Mutagenesis
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Environmental and Molecular Mutagenesis
17 publications, 0.42%
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Molecular Ecology Resources
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Molecular Ecology Resources
17 publications, 0.42%
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Citations by publishers
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1200
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Elsevier
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Elsevier
1044 publications, 25.57%
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Springer Nature
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Springer Nature
464 publications, 11.36%
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Wiley
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Wiley
387 publications, 9.48%
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Oxford University Press
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Oxford University Press
231 publications, 5.66%
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American Chemical Society (ACS)
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American Chemical Society (ACS)
180 publications, 4.41%
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
158 publications, 3.87%
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American Society for Biochemistry and Molecular Biology
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American Society for Biochemistry and Molecular Biology
157 publications, 3.85%
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Taylor & Francis
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Taylor & Francis
115 publications, 2.82%
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Public Library of Science (PLoS)
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Public Library of Science (PLoS)
93 publications, 2.28%
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American Society for Microbiology
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American Society for Microbiology
83 publications, 2.03%
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Proceedings of the National Academy of Sciences (PNAS)
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Proceedings of the National Academy of Sciences (PNAS)
74 publications, 1.81%
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Frontiers Media S.A.
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Frontiers Media S.A.
57 publications, 1.4%
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Royal Society of Chemistry (RSC)
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Royal Society of Chemistry (RSC)
44 publications, 1.08%
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Pleiades Publishing
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Pleiades Publishing
42 publications, 1.03%
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Annual Reviews
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Annual Reviews
33 publications, 0.81%
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American Association for the Advancement of Science (AAAS)
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American Association for the Advancement of Science (AAAS)
32 publications, 0.78%
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The Royal Society
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The Royal Society
29 publications, 0.71%
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Mary Ann Liebert
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Mary Ann Liebert
26 publications, 0.64%
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American Association for Cancer Research (AACR)
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American Association for Cancer Research (AACR)
20 publications, 0.49%
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Hindawi Limited
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Hindawi Limited
16 publications, 0.39%
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Cambridge University Press
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Cambridge University Press
15 publications, 0.37%
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Genetics Society of America
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Genetics Society of America
15 publications, 0.37%
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Cold Spring Harbor Laboratory
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Cold Spring Harbor Laboratory
14 publications, 0.34%
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SAGE
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SAGE
13 publications, 0.32%
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EMBO press
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EMBO press
11 publications, 0.27%
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Canadian Science Publishing
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Canadian Science Publishing
10 publications, 0.24%
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Impact Journals
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Impact Journals
10 publications, 0.24%
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Biophysical Society
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Biophysical Society
9 publications, 0.22%
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Portland Press
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Portland Press
9 publications, 0.22%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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MLA
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RIS
Copy
TY - JOUR
DO - 10.1038/362709a0
UR - https://doi.org/10.1038%2F362709a0
TI - Instability and decay of the primary structure of DNA
T2 - Nature
AU - Lindahl, Tomas
PY - 1993
DA - 1993/04/01 00:00:00
PB - Springer Nature
SP - 709-715
IS - 6422
VL - 362
SN - 0028-0836
SN - 1476-4687
ER -
Cite this
BibTex
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@article{1993_Lindahl
author = {Tomas Lindahl},
title = {Instability and decay of the primary structure of DNA},
journal = {Nature},
year = {1993},
volume = {362},
publisher = {Springer Nature},
month = {apr},
url = {https://doi.org/10.1038%2F362709a0},
number = {6422},
pages = {709--715},
doi = {10.1038/362709a0}
}
Cite this
MLA
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Lindahl, Tomas. “Instability and decay of the primary structure of DNA.” Nature, vol. 362, no. 6422, Apr. 1993, pp. 709-715. https://doi.org/10.1038%2F362709a0.