Nature, volume 529, issue 7586, pages 336-343

Antibacterial drug discovery in the resistance era

BROWN Eric D. 1, 2
Wright Gerard D. 1, 2
1
 
Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada
2
 
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada
Publication typeJournal Article
Publication date2016-01-19
Journal: Nature
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor64.8
ISSN00280836, 14764687
Multidisciplinary
Abstract
The looming antibiotic-resistance crisis has penetrated the consciousness of clinicians, researchers, policymakers, politicians and the public at large. The evolution and widespread distribution of antibiotic-resistance elements in bacterial pathogens has made diseases that were once easily treatable deadly again. Unfortunately, accompanying the rise in global resistance is a failure in antibacterial drug discovery. Lessons from the history of antibiotic discovery and fresh understanding of antibiotic action and the cell biology of microorganisms have the potential to deliver twenty-first century medicines that are able to control infection in the resistance era.

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GOST |
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GOST Copy
BROWN E. et al. Antibacterial drug discovery in the resistance era // Nature. 2016. Vol. 529. No. 7586. pp. 336-343.
GOST all authors (up to 50) Copy
BROWN E., Wright G. Antibacterial drug discovery in the resistance era // Nature. 2016. Vol. 529. No. 7586. pp. 336-343.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1038/nature17042
UR - https://doi.org/10.1038%2Fnature17042
TI - Antibacterial drug discovery in the resistance era
T2 - Nature
AU - BROWN, Eric D.
AU - Wright, Gerard D.
PY - 2016
DA - 2016/01/19 00:00:00
PB - Springer Nature
SP - 336-343
IS - 7586
VL - 529
SN - 0028-0836
SN - 1476-4687
ER -
BibTex |
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BibTex Copy
@article{2016_BROWN
author = {Eric D. BROWN and Gerard D. Wright},
title = {Antibacterial drug discovery in the resistance era},
journal = {Nature},
year = {2016},
volume = {529},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1038%2Fnature17042},
number = {7586},
pages = {336--343},
doi = {10.1038/nature17042}
}
MLA
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MLA Copy
BROWN, Eric D., et al. “Antibacterial drug discovery in the resistance era.” Nature, vol. 529, no. 7586, Jan. 2016, pp. 336-343. https://doi.org/10.1038%2Fnature17042.
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