British Journal of Pharmacology, volume 151, issue 8, pages 1154-1165
Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease
Publication type: Journal Article
Publication date: 2007-08-01
Journal:
British Journal of Pharmacology
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 7.3
ISSN: 00071188, 14765381
PubMed ID:
17519949
Pharmacology
Abstract
Mitochondria play a central role in cell life and death and are known to be important in a wide range of diseases including the cancer, diabetes, cardiovascular disease, and the age-related neurodegenerative diseases. The unique structural and functional characteristics of mitochondria enable the selective targeting of drugs designed to modulate the function of this organelle for therapeutic gain. This review discusses mitochondrial drug targeting strategies and a variety of novel mitochondrial drug targets including the electron transport chain, mitochondrial permeability transition, Bcl-2 family proteins and mitochondrial DNA. Mitochondrial drug-targeting strategies will open up avenues for manipulating mitochondrial functions and allow for selective protection or eradication of cells for therapeutic gain in a variety of diseases. British Journal of Pharmacology (2007) 151, 1154–1165; doi:10.1038/sj.bjp.0707288
Citations by journals
|
1
2
3
4
5
|
|
|
Mitochondrion
|
Mitochondrion
5 publications, 2.98%
|
|
Antioxidants
|
Antioxidants
3 publications, 1.79%
|
|
Journal of Inorganic Biochemistry
|
Journal of Inorganic Biochemistry
3 publications, 1.79%
|
|
Bioorganic and Medicinal Chemistry Letters
|
Bioorganic and Medicinal Chemistry Letters
3 publications, 1.79%
|
|
Neural Regeneration Research
|
Neural Regeneration Research
3 publications, 1.79%
|
|
Journal of Clinical Investigation
|
Journal of Clinical Investigation
2 publications, 1.19%
|
|
Antioxidants and Redox Signaling
|
Antioxidants and Redox Signaling
2 publications, 1.19%
|
|
International Journal of Molecular Sciences
|
International Journal of Molecular Sciences
2 publications, 1.19%
|
|
Scientific Reports
|
Scientific Reports
2 publications, 1.19%
|
|
Acta Pharmacologica Sinica
|
Acta Pharmacologica Sinica
2 publications, 1.19%
|
|
Neurochemical Research
|
Neurochemical Research
2 publications, 1.19%
|
|
Nature Reviews Drug Discovery
|
Nature Reviews Drug Discovery
2 publications, 1.19%
|
|
Translational Stroke Research
|
Translational Stroke Research
2 publications, 1.19%
|
|
Journal of Drug Delivery Science and Technology
|
Journal of Drug Delivery Science and Technology
2 publications, 1.19%
|
|
Sensors and Actuators, B: Chemical
|
Sensors and Actuators, B: Chemical
2 publications, 1.19%
|
|
Biomaterials
|
Biomaterials
2 publications, 1.19%
|
|
Current Opinion in Chemical Biology
|
Current Opinion in Chemical Biology
2 publications, 1.19%
|
|
Food and Chemical Toxicology
|
Food and Chemical Toxicology
2 publications, 1.19%
|
|
Journal of Controlled Release
|
Journal of Controlled Release
2 publications, 1.19%
|
|
Bioorganic and Medicinal Chemistry
|
Bioorganic and Medicinal Chemistry
2 publications, 1.19%
|
|
Molecular Pharmaceutics
|
Molecular Pharmaceutics
2 publications, 1.19%
|
|
Journal of the American Chemical Society
|
Journal of the American Chemical Society
2 publications, 1.19%
|
|
Chemical Science
|
Chemical Science
2 publications, 1.19%
|
|
Evidence-based Complementary and Alternative Medicine
|
Evidence-based Complementary and Alternative Medicine
2 publications, 1.19%
|
|
Archiv der Pharmazie
|
Archiv der Pharmazie
1 publication, 0.6%
|
|
Molecular Biology Reports
|
Molecular Biology Reports
1 publication, 0.6%
|
|
Current Medicinal Chemistry
|
Current Medicinal Chemistry
1 publication, 0.6%
|
|
Medecine/Sciences
|
Medecine/Sciences, 1, 0.6%
Medecine/Sciences
1 publication, 0.6%
|
|
Translational Vision Science and Technology
|
Translational Vision Science and Technology
1 publication, 0.6%
|
|
1
2
3
4
5
|
Citations by publishers
|
10
20
30
40
50
60
|
|
|
Elsevier
|
Elsevier
54 publications, 32.14%
|
|
Springer Nature
|
Springer Nature
24 publications, 14.29%
|
|
Wiley
|
Wiley
14 publications, 8.33%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
12 publications, 7.14%
|
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
10 publications, 5.95%
|
|
Royal Society of Chemistry (RSC)
|
Royal Society of Chemistry (RSC)
5 publications, 2.98%
|
|
Taylor & Francis
|
Taylor & Francis
4 publications, 2.38%
|
|
Wolters Kluwer Health
|
Wolters Kluwer Health
3 publications, 1.79%
|
|
Hindawi Limited
|
Hindawi Limited
3 publications, 1.79%
|
|
American Society for Clinical Investigation
|
American Society for Clinical Investigation
2 publications, 1.19%
|
|
Bentham Science
|
Bentham Science
2 publications, 1.19%
|
|
Mary Ann Liebert
|
Mary Ann Liebert
2 publications, 1.19%
|
|
Portland Press
|
Portland Press
2 publications, 1.19%
|
|
Frontiers Media S.A.
|
Frontiers Media S.A.
2 publications, 1.19%
|
|
Editions E D K
|
Editions E D K, 1, 0.6%
Editions E D K
1 publication, 0.6%
|
|
Association for Research in Vision and Ophthalmology (ARVO)
|
Association for Research in Vision and Ophthalmology (ARVO)
1 publication, 0.6%
|
|
Impact Journals
|
Impact Journals
1 publication, 0.6%
|
|
S. Karger AG
|
S. Karger AG
1 publication, 0.6%
|
|
World Scientific
|
World Scientific
1 publication, 0.6%
|
|
Future Science
|
Future Science, 1, 0.6%
Future Science
1 publication, 0.6%
|
|
SAGE
|
SAGE
1 publication, 0.6%
|
|
Higher Education Press
|
Higher Education Press
1 publication, 0.6%
|
|
King Saud University
|
King Saud University
1 publication, 0.6%
|
|
American Society for Biochemistry and Molecular Biology
|
American Society for Biochemistry and Molecular Biology
1 publication, 0.6%
|
|
Oxford University Press
|
Oxford University Press
1 publication, 0.6%
|
|
Zhejiang University Press
|
Zhejiang University Press, 1, 0.6%
Zhejiang University Press
1 publication, 0.6%
|
|
Walter de Gruyter
|
Walter de Gruyter
1 publication, 0.6%
|
|
American Association for Cancer Research (AACR)
|
American Association for Cancer Research (AACR)
1 publication, 0.6%
|
|
American Medical Association (AMA)
|
American Medical Association (AMA)
1 publication, 0.6%
|
|
10
20
30
40
50
60
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2007,2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["","","","","","","","","","","","","","","","","",""],"datasets":[{"label":"Citations number","data":[1,10,14,8,12,7,10,11,9,15,12,6,3,10,10,14,11,5],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["0.6","5.95","8.33","4.76","7.14","4.17","5.95","6.55","5.36","8.93","7.14","3.57","1.79","5.95","5.95","8.33","6.55","2.98"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Mitochondrion","Antioxidants","Journal of Inorganic Biochemistry","Bioorganic and Medicinal Chemistry Letters","Neural Regeneration Research","Journal of Clinical Investigation","Antioxidants and Redox Signaling","International Journal of Molecular Sciences","Scientific Reports","Acta Pharmacologica Sinica","Neurochemical Research","Nature Reviews Drug Discovery","Translational Stroke Research","Journal of Drug Delivery Science and Technology","Sensors and Actuators, B: Chemical","Biomaterials","Current Opinion in Chemical Biology","Food and Chemical Toxicology","Journal of Controlled Release","Bioorganic and Medicinal Chemistry","Molecular Pharmaceutics","Journal of the American Chemical Society","Chemical Science","Evidence-based Complementary and Alternative Medicine","Archiv der Pharmazie","Molecular Biology Reports","Current Medicinal Chemistry","Medecine\/Sciences","Translational Vision Science and Technology"],"ids":[18142,16381,6830,8828,20777,1384,5732,14627,13767,13018,10309,14344,11369,17907,22419,13732,5052,8445,14351,1162,19735,4813,9646,23195,15226,2791,17087,3775,15561],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/aFa86lAy63Pq5tYKiOsH017UsgJA6uk6ed66C0Ns_medium.webp","\/storage\/images\/resized\/Zy5YST233rzRbZP24I24MzZm64hz20ZV9qQopmMn_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp","","\/storage\/images\/resized\/5UMgKnFqPQsuIMt03SiGJWWld9jmDgeekKAEN0Wm_medium.webp"],"datasets":[{"label":"","data":[5,3,3,3,3,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[2.98,1.79,1.79,1.79,1.79,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,1.19,0.6,0.6,0.6,0.6,0.6],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Springer Nature","Wiley","Multidisciplinary Digital Publishing Institute (MDPI)","American Chemical Society (ACS)","Royal Society of Chemistry (RSC)","Taylor & Francis","Wolters Kluwer Health","Hindawi Limited","American Society for Clinical Investigation","Bentham Science","Mary Ann Liebert","Portland Press","Frontiers Media S.A.","Editions E D K","Association for Research in Vision and Ophthalmology (ARVO)","Impact Journals","S. Karger AG","World Scientific","Future Science","SAGE","Higher Education Press","King Saud University","American Society for Biochemistry and Molecular Biology","Oxford University Press","Zhejiang University Press","Walter de Gruyter","American Association for Cancer Research (AACR)","American Medical Association (AMA)"],"ids":[17,8,11,202,40,123,18,32,6921,564,39,230,801,208,1381,1778,342,6998,23,5592,31,321,171,2090,19,1497,4,2286,2676],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/aFa86lAy63Pq5tYKiOsH017UsgJA6uk6ed66C0Ns_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp","\/storage\/images\/resized\/Zy5YST233rzRbZP24I24MzZm64hz20ZV9qQopmMn_medium.webp","\/storage\/images\/resized\/nUqNrP9GnM1t0BrAIXp1LBodjU8aIJ2Fk4pLfGhZ_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","","\/storage\/images\/resized\/5UMgKnFqPQsuIMt03SiGJWWld9jmDgeekKAEN0Wm_medium.webp","\/storage\/images\/resized\/HY0CXgRt044tzIAB16PDvDzdHeKHGtSvlMH0yWf6_medium.webp","\/storage\/images\/resized\/dzjTgJDYMoGfxybjlxLdd3z4gHYG42WZR0UxSYzy_medium.webp","\/storage\/images\/resized\/jZQkhOOcY9wrGwZm7XGRwMe8H7fThQu3KamISuun_medium.webp","","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp","\/storage\/images\/resized\/fzjeYAS7sc3p4k3vIdQIac4L4J6MUyfSbYzJSIAv_medium.webp","\/storage\/images\/resized\/9z7b0TQJNgUxZHYXLrTmbnjJn9y5iq56Wxtqb1Lv_medium.webp","\/storage\/images\/resized\/OuA6WPZekwEiUM99mP2pSqj4yHPxHezM6xgLhAjO_medium.webp","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","","\/storage\/images\/resized\/3SpVxcYL33bOvPq4sHxJLH2NeKNeDloahSUpNiO4_medium.webp","\/storage\/images\/resized\/cfuVw6XIq2mATDNJdXiose3W8qYbkmaVSpHoP8XL_medium.webp","\/storage\/images\/resized\/brnEFyEeTGw9nlsHnEHbyCV6AqrisRCX7QF1dLtY_medium.webp"],"datasets":[{"label":"","data":[54,24,14,12,10,5,4,3,3,2,2,2,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[32.14,14.29,8.33,7.14,5.95,2.98,2.38,1.79,1.79,1.19,1.19,1.19,1.19,1.19,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6,0.6],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Armstrong J. S. Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease // British Journal of Pharmacology. 2007. Vol. 151. No. 8. pp. 1154-1165.
GOST all authors (up to 50)
Copy
Armstrong J. S. Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease // British Journal of Pharmacology. 2007. Vol. 151. No. 8. pp. 1154-1165.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1038/sj.bjp.0707288
UR - https://doi.org/10.1038%2Fsj.bjp.0707288
TI - Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease
T2 - British Journal of Pharmacology
AU - Armstrong, J. S.
PY - 2007
DA - 2007/08/01 00:00:00
PB - Wiley
SP - 1154-1165
IS - 8
VL - 151
PMID - 17519949
SN - 0007-1188
SN - 1476-5381
ER -
Cite this
BibTex
Copy
@article{2007_Armstrong,
author = {J. S. Armstrong},
title = {Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease},
journal = {British Journal of Pharmacology},
year = {2007},
volume = {151},
publisher = {Wiley},
month = {aug},
url = {https://doi.org/10.1038%2Fsj.bjp.0707288},
number = {8},
pages = {1154--1165},
doi = {10.1038/sj.bjp.0707288}
}
Cite this
MLA
Copy
Armstrong, J. S.. “Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease.” British Journal of Pharmacology, vol. 151, no. 8, Aug. 2007, pp. 1154-1165. https://doi.org/10.1038%2Fsj.bjp.0707288.