Open Access
Open access
Nucleic Acids Research, volume 42, issue D1, pages D98-D103

NONCODEv4: exploring the world of long non-coding RNA genes

Xie Chaoyong
Yuan Jiao
Li Hui
Li Ming
Zhao Guoguang
Bu Dechao
Zhu Weimin
Wu Wei
Wu Di
Zhao Yi
Publication typeJournal Article
Publication date2013-11-26
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor14.9
ISSN03051048, 13624962
PubMed ID:  24285305
Genetics
Abstract
NONCODE (http://www.bioinfo.org/noncode/) is an integrated knowledge database dedicated to non-coding RNAs (excluding tRNAs and rRNAs). Non-coding RNAs (ncRNAs) have been implied in diseases and identified to play important roles in various biological processes. Since NONCODE version 3.0 was released 2 years ago, discovery of novel ncRNAs has been promoted by high-throughput RNA sequencing (RNA-Seq). In this update of NONCODE, we expand the ncRNA data set by collection of newly identified ncRNAs from literature published in the last 2 years and integration of the latest version of RefSeq and Ensembl. Particularly, the number of long non-coding RNA (lncRNA) has increased sharply from 73 327 to 210 831. Owing to similar alternative splicing pattern to mRNAs, the concept of lncRNA genes was put forward to help systematic understanding of lncRNAs. The 56 018 and 46 475 lncRNA genes were generated from 95 135 and 67 628 lncRNAs for human and mouse, respectively. Additionally, we present expression profile of lncRNA genes by graphs based on public RNA-seq data for human and mouse, as well as predict functions of these lncRNA genes. The improvements brought to the database also include an incorporation of an ID conversion tool from RefSeq or Ensembl ID to NONCODE ID and a service of lncRNA identification. NONCODE is also accessible through http://www.noncode.org/.

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GOST |
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GOST Copy
Xie C. et al. NONCODEv4: exploring the world of long non-coding RNA genes // Nucleic Acids Research. 2013. Vol. 42. No. D1. p. D98-D103.
GOST all authors (up to 50) Copy
Xie C., Yuan J., Li H., Li M., Zhao G., Bu D., Zhu W., Wu W., Wu D., Zhao Y. NONCODEv4: exploring the world of long non-coding RNA genes // Nucleic Acids Research. 2013. Vol. 42. No. D1. p. D98-D103.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1093/nar/gkt1222
UR - https://doi.org/10.1093%2Fnar%2Fgkt1222
TI - NONCODEv4: exploring the world of long non-coding RNA genes
T2 - Nucleic Acids Research
AU - Xie, Chaoyong
AU - Yuan, Jiao
AU - Li, Hui
AU - Li, Ming
AU - Zhao, Guoguang
AU - Bu, Dechao
AU - Zhu, Weimin
AU - Wu, Wei
AU - Wu, Di
AU - Zhao, Yi
PY - 2013
DA - 2013/11/26 00:00:00
PB - Oxford University Press
SP - D98-D103
IS - D1
VL - 42
PMID - 24285305
SN - 0305-1048
SN - 1362-4962
ER -
BibTex |
Cite this
BibTex Copy
@article{2013_Xie,
author = {Chaoyong Xie and Jiao Yuan and Hui Li and Ming Li and Guoguang Zhao and Dechao Bu and Weimin Zhu and Wei Wu and Di Wu and Yi Zhao},
title = {NONCODEv4: exploring the world of long non-coding RNA genes},
journal = {Nucleic Acids Research},
year = {2013},
volume = {42},
publisher = {Oxford University Press},
month = {nov},
url = {https://doi.org/10.1093%2Fnar%2Fgkt1222},
number = {D1},
pages = {D98--D103},
doi = {10.1093/nar/gkt1222}
}
MLA
Cite this
MLA Copy
Xie, Chaoyong, et al. “NONCODEv4: exploring the world of long non-coding RNA genes.” Nucleic Acids Research, vol. 42, no. D1, Nov. 2013, pp. D98-D103. https://doi.org/10.1093%2Fnar%2Fgkt1222.
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