Pancreas, volume 39, issue 4, pages 425-435
Phenotype and Genotype of Pancreatic Cancer Cell Lines
Deer Emily L.
1
,
González-Hernández Jessica
2, 3
,
Coursen Jill D.
3
,
Shea Jill E.
3
,
Ngatia Josephat
3, 4
,
Scaife Courtney L
3
,
Firpo Matthew A.
3
,
Mulvihill Sean J.
3
1
Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA.
|
2
University of Puerto Rico
|
3
University Of Utah
|
4
University Of Florida
|
Publication type: Journal Article
Publication date: 2010-04-16
PubMed ID:
20418756
Endocrinology
Endocrinology, Diabetes and Metabolism
Hepatology
Internal Medicine
Abstract
Abstract The dismal prognosis of pancreatic adenocarcinoma is due in part to a lack of molecular information regarding disease development. Established cell lines remain a useful tool for investigating these molecular events. Here we present a review of available information on commonly used pancreatic adenocarcinoma cell lines as a resource to help investigators select the cell lines most appropriate for their particular research needs. Information on clinical history; in vitro and in vivo growth characteristics; phenotypic characteristics, such as adhesion, invasion, migration, and tumorigenesis; and genotypic status of commonly altered genes (KRAS, p53, p16, and SMAD4) was evaluated. Identification of both consensus and discrepant information in the literature suggests careful evaluation before selection of cell lines and attention be given to cell line authentication.
Citations by journals
5
10
15
20
25
30
35
|
|
Cancers
|
Cancers
34 publications, 4.86%
|
Oncotarget
|
Oncotarget
30 publications, 4.29%
|
PLoS ONE
|
PLoS ONE
28 publications, 4.01%
|
Scientific Reports
|
Scientific Reports
22 publications, 3.15%
|
International Journal of Molecular Sciences
|
International Journal of Molecular Sciences
18 publications, 2.58%
|
Pancreas
|
Pancreas
15 publications, 2.15%
|
Cancer Research
|
Cancer Research
13 publications, 1.86%
|
Cells
|
Cells
12 publications, 1.72%
|
Cancer Letters
|
Cancer Letters
12 publications, 1.72%
|
Advances in Biological Regulation
|
Advances in Biological Regulation
9 publications, 1.29%
|
BMC Cancer
|
BMC Cancer
8 publications, 1.14%
|
International Journal of Oncology
|
International Journal of Oncology
7 publications, 1%
|
Biomedicines
|
Biomedicines
7 publications, 1%
|
Frontiers in Oncology
|
Frontiers in Oncology
7 publications, 1%
|
Cancer Cell International
|
Cancer Cell International
7 publications, 1%
|
Oncology Reports
|
Oncology Reports
6 publications, 0.86%
|
Frontiers in Cell and Developmental Biology
|
Frontiers in Cell and Developmental Biology
6 publications, 0.86%
|
Journal of Experimental and Clinical Cancer Research
|
Journal of Experimental and Clinical Cancer Research
6 publications, 0.86%
|
Nature Communications
|
Nature Communications
6 publications, 0.86%
|
Carcinogenesis
|
Carcinogenesis
6 publications, 0.86%
|
Clinical Cancer Research
|
Clinical Cancer Research
6 publications, 0.86%
|
Frontiers in Immunology
|
Frontiers in Immunology
5 publications, 0.72%
|
Cellular oncology (Dordrecht)
|
Cellular oncology (Dordrecht)
5 publications, 0.72%
|
Cell Reports
|
Cell Reports
5 publications, 0.72%
|
International Journal of Pharmaceutics
|
International Journal of Pharmaceutics
5 publications, 0.72%
|
Molecular Cancer Therapeutics
|
Molecular Cancer Therapeutics
5 publications, 0.72%
|
Aging
|
Aging
4 publications, 0.57%
|
Cell Death and Disease
|
Cell Death and Disease
4 publications, 0.57%
|
Oncogene
|
Oncogene
4 publications, 0.57%
|
5
10
15
20
25
30
35
|
Citations by publishers
20
40
60
80
100
120
140
|
|
Elsevier
|
Elsevier
124 publications, 17.74%
|
Springer Nature
|
Springer Nature
120 publications, 17.17%
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
89 publications, 12.73%
|
Wiley
|
Wiley
50 publications, 7.15%
|
Impact Journals
|
Impact Journals
34 publications, 4.86%
|
Public Library of Science (PLoS)
|
Public Library of Science (PLoS)
29 publications, 4.15%
|
American Association for Cancer Research (AACR)
|
American Association for Cancer Research (AACR)
29 publications, 4.15%
|
Frontiers Media S.A.
|
Frontiers Media S.A.
22 publications, 3.15%
|
Wolters Kluwer Health
|
Wolters Kluwer Health
20 publications, 2.86%
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
17 publications, 2.43%
|
Spandidos Publications
|
Spandidos Publications
14 publications, 2%
|
Royal Society of Chemistry (RSC)
|
Royal Society of Chemistry (RSC)
14 publications, 2%
|
Taylor & Francis
|
Taylor & Francis
13 publications, 1.86%
|
SAGE
|
SAGE
8 publications, 1.14%
|
Oxford University Press
|
Oxford University Press
6 publications, 0.86%
|
American Society for Biochemistry and Molecular Biology
|
American Society for Biochemistry and Molecular Biology
5 publications, 0.72%
|
Hindawi Limited
|
Hindawi Limited
5 publications, 0.72%
|
AME Publishing Company
|
AME Publishing Company
5 publications, 0.72%
|
Mary Ann Liebert
|
Mary Ann Liebert
4 publications, 0.57%
|
American Association for the Advancement of Science (AAAS)
|
American Association for the Advancement of Science (AAAS)
4 publications, 0.57%
|
Baishideng Publishing Group
|
Baishideng Publishing Group
3 publications, 0.43%
|
Proceedings of the National Academy of Sciences (PNAS)
|
Proceedings of the National Academy of Sciences (PNAS)
3 publications, 0.43%
|
Pleiades Publishing
|
Pleiades Publishing
2 publications, 0.29%
|
Neoplasia Press
|
Neoplasia Press, 2, 0.29%
Neoplasia Press
2 publications, 0.29%
|
Federation of American Societies for Experimental Biology (FASEB)
|
Federation of American Societies for Experimental Biology (FASEB)
2 publications, 0.29%
|
American Society for Microbiology
|
American Society for Microbiology
2 publications, 0.29%
|
Walter de Gruyter
|
Walter de Gruyter
2 publications, 0.29%
|
eLife Sciences Publications
|
eLife Sciences Publications
2 publications, 0.29%
|
Rockefeller University Press
|
Rockefeller University Press
2 publications, 0.29%
|
20
40
60
80
100
120
140
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["","","","","","","","","","","","","","",""],"datasets":[{"label":"Citations number","data":[1,8,23,15,47,34,63,67,64,67,76,81,79,59,15],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["0.14","1.14","3.29","2.15","6.72","4.86","9.01","9.59","9.16","9.59","10.87","11.59","11.3","8.44","2.15"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Cancers","Oncotarget","PLoS ONE","Scientific Reports","International Journal of Molecular Sciences","Pancreas","Cancer Research","Cells","Cancer Letters","Advances in Biological Regulation","BMC Cancer","International Journal of Oncology","Biomedicines","Frontiers in Oncology","Cancer Cell International","Oncology Reports","Frontiers in Cell and Developmental Biology","Journal of Experimental and Clinical Cancer Research","Nature Communications","Carcinogenesis","Clinical Cancer Research","Frontiers in Immunology","Cellular oncology (Dordrecht)","Cell Reports","International Journal of Pharmaceutics","Molecular Cancer Therapeutics","Aging","Cell Death and Disease","Oncogene"],"ids":[22471,8484,24963,13767,14627,8074,11199,25293,1654,1953,6868,18049,24421,10990,9737,18785,12128,5741,3231,4464,6723,1699,11996,9130,3305,16265,780,25236,20423],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/HY0CXgRt044tzIAB16PDvDzdHeKHGtSvlMH0yWf6_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/cfuVw6XIq2mATDNJdXiose3W8qYbkmaVSpHoP8XL_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/8zKfOwdd5XirYzTQfqwp7U8IEQc8ckIOjyYQSBkk_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/8zKfOwdd5XirYzTQfqwp7U8IEQc8ckIOjyYQSBkk_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","\/storage\/images\/resized\/cfuVw6XIq2mATDNJdXiose3W8qYbkmaVSpHoP8XL_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/cfuVw6XIq2mATDNJdXiose3W8qYbkmaVSpHoP8XL_medium.webp","\/storage\/images\/resized\/HY0CXgRt044tzIAB16PDvDzdHeKHGtSvlMH0yWf6_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp"],"datasets":[{"label":"","data":[34,30,28,22,18,15,13,12,12,9,8,7,7,7,7,6,6,6,6,6,6,5,5,5,5,5,4,4,4],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[4.86,4.29,4.01,3.15,2.58,2.15,1.86,1.72,1.72,1.29,1.14,1,1,1,1,0.86,0.86,0.86,0.86,0.86,0.86,0.72,0.72,0.72,0.72,0.72,0.57,0.57,0.57],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Springer Nature","Multidisciplinary Digital Publishing Institute (MDPI)","Wiley","Impact Journals","Public Library of Science (PLoS)","American Association for Cancer Research (AACR)","Frontiers Media S.A.","Wolters Kluwer Health","American Chemical Society (ACS)","Spandidos Publications","Royal Society of Chemistry (RSC)","Taylor & Francis","SAGE","Oxford University Press","American Society for Biochemistry and Molecular Biology","Hindawi Limited","AME Publishing Company","Mary Ann Liebert","American Association for the Advancement of Science (AAAS)","Baishideng Publishing Group","Proceedings of the National Academy of Sciences (PNAS)","Pleiades Publishing","Neoplasia Press","Federation of American Societies for Experimental Biology (FASEB)","American Society for Microbiology","Walter de Gruyter","eLife Sciences Publications","Rockefeller University Press"],"ids":[17,8,202,11,342,344,2286,208,32,40,1097,123,18,31,19,2090,6921,1566,230,189,7719,162,101,4513,3243,142,4,6627,22],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/HY0CXgRt044tzIAB16PDvDzdHeKHGtSvlMH0yWf6_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/cfuVw6XIq2mATDNJdXiose3W8qYbkmaVSpHoP8XL_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/8zKfOwdd5XirYzTQfqwp7U8IEQc8ckIOjyYQSBkk_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","\/storage\/images\/resized\/OuA6WPZekwEiUM99mP2pSqj4yHPxHezM6xgLhAjO_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/PYBAYQjpFdxPQPRGY3kU5Xzbu0W7K7umVNk0TY9i_medium.webp","\/storage\/images\/resized\/Zy5YST233rzRbZP24I24MzZm64hz20ZV9qQopmMn_medium.webp","\/storage\/images\/resized\/s10mcsCV4OAUg9O2KrqOquQC0PhyLMI8hUUkuflM_medium.webp","\/storage\/images\/resized\/bKOjgSt9mSGUD9fzKZyqcKSIgDCDSMd1ZWjJOZzx_medium.webp","\/storage\/images\/resized\/mxFdPe9qujsfvfYfcN0QOclAiYORFb0xrRlwV8gs_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","","\/storage\/images\/resized\/dfTCxFYwjmdhSAwAcIOV9PfBdAN17zTMvybxH2kG_medium.webp","\/storage\/images\/resized\/VPE7q24PXoHr5SS2SqfEgxccSMUxWLfZINOX60uo_medium.webp","\/storage\/images\/resized\/3SpVxcYL33bOvPq4sHxJLH2NeKNeDloahSUpNiO4_medium.webp","\/storage\/images\/resized\/eIZgkq1MRZyJ3hBkdupnUUv7wgB6zCl9D99SlPN5_medium.webp","\/storage\/images\/resized\/lEA1FyUnFAZR1DchuczZi5bjAixG3TNeWVz6oF4R_medium.webp"],"datasets":[{"label":"","data":[124,120,89,50,34,29,29,22,20,17,14,14,13,8,6,5,5,5,4,4,3,3,2,2,2,2,2,2,2],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[17.74,17.17,12.73,7.15,4.86,4.15,4.15,3.15,2.86,2.43,2,2,1.86,1.14,0.86,0.72,0.72,0.72,0.57,0.57,0.43,0.43,0.29,0.29,0.29,0.29,0.29,0.29,0.29],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Deer E. L. et al. Phenotype and Genotype of Pancreatic Cancer Cell Lines // Pancreas. 2010. Vol. 39. No. 4. pp. 425-435.
GOST all authors (up to 50)
Copy
Deer E. L., González-Hernández J., Coursen J. D., Shea J. E., Ngatia J., Scaife C. L., Firpo M. A., Mulvihill S. J. Phenotype and Genotype of Pancreatic Cancer Cell Lines // Pancreas. 2010. Vol. 39. No. 4. pp. 425-435.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1097/MPA.0b013e3181c15963
UR - https://doi.org/10.1097%2FMPA.0b013e3181c15963
TI - Phenotype and Genotype of Pancreatic Cancer Cell Lines
T2 - Pancreas
AU - Deer, Emily L.
AU - González-Hernández, Jessica
AU - Coursen, Jill D.
AU - Shea, Jill E.
AU - Ngatia, Josephat
AU - Scaife, Courtney L
AU - Firpo, Matthew A.
AU - Mulvihill, Sean J.
PY - 2010
DA - 2010/04/16 00:00:00
PB - Wolters Kluwer Health
SP - 425-435
IS - 4
VL - 39
PMID - 20418756
SN - 0885-3177
SN - 1536-4828
ER -
Cite this
BibTex
Copy
@article{2010_Deer
author = {Emily L. Deer and Jessica González-Hernández and Jill D. Coursen and Jill E. Shea and Josephat Ngatia and Courtney L Scaife and Matthew A. Firpo and Sean J. Mulvihill},
title = {Phenotype and Genotype of Pancreatic Cancer Cell Lines},
journal = {Pancreas},
year = {2010},
volume = {39},
publisher = {Wolters Kluwer Health},
month = {apr},
url = {https://doi.org/10.1097%2FMPA.0b013e3181c15963},
number = {4},
pages = {425--435},
doi = {10.1097/MPA.0b013e3181c15963}
}
Cite this
MLA
Copy
Deer, Emily L., et al. “Phenotype and Genotype of Pancreatic Cancer Cell Lines.” Pancreas, vol. 39, no. 4, Apr. 2010, pp. 425-435. https://doi.org/10.1097%2FMPA.0b013e3181c15963.