Open Access
FEMS Microbiology Reviews, volume 38, issue 2, pages 144-171
Biology of telomeres: lessons from budding yeast
Publication type: Journal Article
Publication date: 2014-03-01
Journal:
FEMS Microbiology Reviews
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 11.3
ISSN: 01686445, 15746976
Microbiology
Infectious Diseases
Abstract
Telomeres are nucleoprotein structures that cap the ends of the linear eukaryotic chromosomes and thereby protect their stability and integrity. Telomeres play central roles in maintaining the genome's integrity, distinguishing between the natural chromosomal ends and unwanted double-stranded breaks. In addition, telomeres are replicated by a special reverse transcriptase called telomerase, in a complex mechanism that is coordinated with the genome's replication. Telomeres also play an important role in tethering the chromosomes to the nuclear envelope, thus helping in positioning the chromosomes within the nucleus. The special chromatin configuration of telomeres affects the expression of nearby genes; nonetheless, telomeres are transcribed, creating noncoding RNA molecules that hybridize to the chromosomal ends and seem to play regulatory roles. The yeast Saccharomyces cerevisiae, with its sophisticated genetics and molecular biology, has provided many fundamental concepts in telomere biology, which were later found to be conserved in all organisms. Here, we present an overview of all the aspects of telomere biology investigated in yeast, which continues to provide new insights into this complex and important subject, which has significant medical implications, especially in the fields of aging and cancer.
Citations by journals
|
1
2
3
4
5
6
7
|
|
|
Current Genetics
|
Current Genetics
7 publications, 8.54%
|
|
PLoS Genetics
|
PLoS Genetics
6 publications, 7.32%
|
|
Genetics
|
Genetics
5 publications, 6.1%
|
|
Cells
|
Cells
4 publications, 4.88%
|
|
BMC Genomics
|
BMC Genomics
2 publications, 2.44%
|
|
Genes
|
Genes
2 publications, 2.44%
|
|
International Journal of Molecular Sciences
|
International Journal of Molecular Sciences
2 publications, 2.44%
|
|
Frontiers in Genetics
|
Frontiers in Genetics
2 publications, 2.44%
|
|
Scientific Reports
|
Scientific Reports
2 publications, 2.44%
|
|
DNA Repair
|
DNA Repair
2 publications, 2.44%
|
|
Yeast
|
Yeast
2 publications, 2.44%
|
|
Molecular Biology of the Cell
|
Molecular Biology of the Cell
2 publications, 2.44%
|
|
Nucleic Acids Research
|
Nucleic Acids Research
2 publications, 2.44%
|
|
Journal of Cell Biology
|
Journal of Cell Biology
2 publications, 2.44%
|
|
G3: Genes, Genomes, Genetics
|
G3: Genes, Genomes, Genetics
2 publications, 2.44%
|
|
Aging
|
Aging
1 publication, 1.22%
|
|
ACS Synthetic Biology
|
ACS Synthetic Biology
1 publication, 1.22%
|
|
Cancer Gene Therapy
|
Cancer Gene Therapy
1 publication, 1.22%
|
|
Genetica
|
Genetica
1 publication, 1.22%
|
|
BMC Biology
|
BMC Biology
1 publication, 1.22%
|
|
Cell Biochemistry and Biophysics
|
Cell Biochemistry and Biophysics
1 publication, 1.22%
|
|
BMC Genetics
|
BMC Genetics
1 publication, 1.22%
|
|
PLoS ONE
|
PLoS ONE
1 publication, 1.22%
|
|
Mutation Research - Reviews in Mutation Research
|
Mutation Research - Reviews in Mutation Research
1 publication, 1.22%
|
|
Mayo Clinic Proceedings
|
Mayo Clinic Proceedings
1 publication, 1.22%
|
|
Fungal Biology
|
Fungal Biology
1 publication, 1.22%
|
|
Journal of Molecular Biology
|
Journal of Molecular Biology
1 publication, 1.22%
|
|
Mechanisms of Ageing and Development
|
Mechanisms of Ageing and Development
1 publication, 1.22%
|
|
iScience
|
iScience
1 publication, 1.22%
|
|
1
2
3
4
5
6
7
|
Citations by publishers
|
2
4
6
8
10
12
14
16
18
|
|
|
Springer Nature
|
Springer Nature
17 publications, 20.73%
|
|
Elsevier
|
Elsevier
9 publications, 10.98%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
8 publications, 9.76%
|
|
Public Library of Science (PLoS)
|
Public Library of Science (PLoS)
7 publications, 8.54%
|
|
Genetics Society of America
|
Genetics Society of America
7 publications, 8.54%
|
|
Oxford University Press
|
Oxford University Press
4 publications, 4.88%
|
|
Wiley
|
Wiley
3 publications, 3.66%
|
|
Frontiers Media S.A.
|
Frontiers Media S.A.
2 publications, 2.44%
|
|
American Society for Cell Biology (ASCB)
|
American Society for Cell Biology (ASCB)
2 publications, 2.44%
|
|
Rockefeller University Press
|
Rockefeller University Press
2 publications, 2.44%
|
|
Impact Journals
|
Impact Journals
1 publication, 1.22%
|
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
1 publication, 1.22%
|
|
Taylor & Francis
|
Taylor & Francis
1 publication, 1.22%
|
|
American Society of Plant Biologists
|
American Society of Plant Biologists
1 publication, 1.22%
|
|
EMBO press
|
EMBO press
1 publication, 1.22%
|
|
American Society for Microbiology
|
American Society for Microbiology
1 publication, 1.22%
|
|
Proceedings of the National Academy of Sciences (PNAS)
|
Proceedings of the National Academy of Sciences (PNAS)
1 publication, 1.22%
|
|
Annual Reviews
|
Annual Reviews
1 publication, 1.22%
|
|
2
4
6
8
10
12
14
16
18
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2015,2016,2017,2018,2019,2020,2021,2022,2023],"ids":[0,0,0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0,0,0],"imageUrls":["","","","","","","","",""],"datasets":[{"label":"Citations number","data":[4,10,14,6,11,7,10,11,9],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["4.88","12.2","17.07","7.32","13.41","8.54","12.2","13.41","10.98"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Current Genetics","PLoS Genetics","Genetics","Cells","BMC Genomics","Genes","International Journal of Molecular Sciences","Frontiers in Genetics","Scientific Reports","DNA Repair","Yeast","Molecular Biology of the Cell","Nucleic Acids Research","Journal of Cell Biology","G3: Genes, Genomes, Genetics","Aging","ACS Synthetic Biology","Cancer Gene Therapy","Genetica","BMC Biology","Cell Biochemistry and Biophysics","BMC Genetics","PLoS ONE","Mutation Research - Reviews in Mutation Research","Mayo Clinic Proceedings","Fungal Biology","Journal of Molecular Biology","Mechanisms of Ageing and Development","iScience"],"ids":[16818,785,10675,25293,7708,8879,14627,13242,13767,13424,11674,18406,23904,867,14038,780,5908,9086,19830,8160,2005,4042,24963,7208,3659,11372,19701,18301,6073],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/9EVpRifnnUJt6oHGY5GfsfSXTEz5wzbdgnZqiF5m_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/1pFWD0EzQnc5egizpglbyNDhAbHCAVj1O7hBchfP_medium.webp","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","\/storage\/images\/resized\/lEA1FyUnFAZR1DchuczZi5bjAixG3TNeWVz6oF4R_medium.webp","\/storage\/images\/resized\/9EVpRifnnUJt6oHGY5GfsfSXTEz5wzbdgnZqiF5m_medium.webp","\/storage\/images\/resized\/HY0CXgRt044tzIAB16PDvDzdHeKHGtSvlMH0yWf6_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[7,6,5,4,2,2,2,2,2,2,2,2,2,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[8.54,7.32,6.1,4.88,2.44,2.44,2.44,2.44,2.44,2.44,2.44,2.44,2.44,2.44,2.44,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Springer Nature","Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","Public Library of Science (PLoS)","Genetics Society of America","Oxford University Press","Wiley","Frontiers Media S.A.","American Society for Cell Biology (ASCB)","Rockefeller University Press","Impact Journals","American Chemical Society (ACS)","Taylor & Francis","American Society of Plant Biologists","EMBO press","American Society for Microbiology","Proceedings of the National Academy of Sciences (PNAS)","Annual Reviews"],"ids":[8,17,202,344,3356,19,11,208,4151,22,342,40,18,2122,9415,142,162,6941],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/9EVpRifnnUJt6oHGY5GfsfSXTEz5wzbdgnZqiF5m_medium.webp","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/1pFWD0EzQnc5egizpglbyNDhAbHCAVj1O7hBchfP_medium.webp","\/storage\/images\/resized\/lEA1FyUnFAZR1DchuczZi5bjAixG3TNeWVz6oF4R_medium.webp","\/storage\/images\/resized\/HY0CXgRt044tzIAB16PDvDzdHeKHGtSvlMH0yWf6_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/JLpI53lI44aNyHLD8xZshTDqAobKeIZXi5qWe93H_medium.webp","\/storage\/images\/resized\/1UiI5HycPsvulDeXOySNp0OuaMMmIKfPnsdKPyH0_medium.webp","\/storage\/images\/resized\/VPE7q24PXoHr5SS2SqfEgxccSMUxWLfZINOX60uo_medium.webp","\/storage\/images\/resized\/mxFdPe9qujsfvfYfcN0QOclAiYORFb0xrRlwV8gs_medium.webp","\/storage\/images\/resized\/A7oGMwx1m3fFJlKJvQUVra8h0itmEa7JZW0q3Q0b_medium.webp"],"datasets":[{"label":"","data":[17,9,8,7,7,4,3,2,2,2,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[20.73,10.98,9.76,8.54,8.54,4.88,3.66,2.44,2.44,2.44,1.22,1.22,1.22,1.22,1.22,1.22,1.22,1.22],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Kupiec M. Biology of telomeres: lessons from budding yeast // FEMS Microbiology Reviews. 2014. Vol. 38. No. 2. pp. 144-171.
GOST all authors (up to 50)
Copy
Kupiec M. Biology of telomeres: lessons from budding yeast // FEMS Microbiology Reviews. 2014. Vol. 38. No. 2. pp. 144-171.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1111/1574-6976.12054
UR - https://doi.org/10.1111%2F1574-6976.12054
TI - Biology of telomeres: lessons from budding yeast
T2 - FEMS Microbiology Reviews
AU - Kupiec, Martin
PY - 2014
DA - 2014/03/01 00:00:00
PB - Oxford University Press
SP - 144-171
IS - 2
VL - 38
SN - 0168-6445
SN - 1574-6976
ER -
Cite this
BibTex
Copy
@article{2014_Kupiec,
author = {Martin Kupiec},
title = {Biology of telomeres: lessons from budding yeast},
journal = {FEMS Microbiology Reviews},
year = {2014},
volume = {38},
publisher = {Oxford University Press},
month = {mar},
url = {https://doi.org/10.1111%2F1574-6976.12054},
number = {2},
pages = {144--171},
doi = {10.1111/1574-6976.12054}
}
Cite this
MLA
Copy
Kupiec, Martin. “Biology of telomeres: lessons from budding yeast.” FEMS Microbiology Reviews, vol. 38, no. 2, Mar. 2014, pp. 144-171. https://doi.org/10.1111%2F1574-6976.12054.