Open Access
Journal of Biomedical Optics, volume 21, issue 2, pages 25006
Computational model of bladder tissue based on its measured optical properties
2
State University—Education-Science-Production Complex, Biomedical Photonics Instrumentation Group, Scientific-Educational Centre of “Biomedical Engineering,” Oryol 302020, Russia
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Publication type: Journal Article
Publication date: 2016-02-15
Journal:
Journal of Biomedical Optics
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor: 3.5
ISSN: 10833668, 15602281
Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Biomedical Engineering
Abstract
Urinary bladder diseases are a common problem throughout the world and often difficult to accurately diagnose. Furthermore, they pose a heavy financial burden on health services. Urinary bladder tissue from male pigs was spectrophotometrically measured and the resulting data used to calculate the absorption, transmission, and reflectance parameters, along with the derived coefficients of scattering and absorption. These were employed to create a "generic" computational bladder model based on optical properties, simulating the propagation of photons through the tissue at different wavelengths. Using the Monte-Carlo method and fluorescence spectra of UV and blue excited wavelength, diagnostically important biomarkers were modeled. Additionally, the multifunctional noninvasive diagnostics system "LAKK-M" was used to gather fluorescence data to further provide essential comparisons. The ultimate goal of the study was to successfully simulate the effects of varying excited radiation wavelengths on bladder tissue to determine the effectiveness of photonics diagnostic devices. With increased accuracy, this model could be used to reliably aid in differentiating healthy and pathological tissues within the bladder and potentially other hollow organs.
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Citations by publishers
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Multidisciplinary Digital Publishing Institute (MDPI)
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Pleiades Publishing
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Pleiades Publishing
1 publication, 4.55%
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IEEE
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IEEE
1 publication, 4.55%
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Taylor & Francis
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1 publication, 4.55%
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First Pavlov State Medical University of St. Petersburg
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First Pavlov State Medical University of St. Petersburg
1 publication, 4.55%
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Rafailov I. E. et al. Computational model of bladder tissue based on its measured optical properties // Journal of Biomedical Optics. 2016. Vol. 21. No. 2. p. 25006.
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Rafailov I. E., Dremin V. V., Litvinova K., Dunaev A. V., Socolovski S., Rafailov E. Computational model of bladder tissue based on its measured optical properties // Journal of Biomedical Optics. 2016. Vol. 21. No. 2. p. 25006.
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TY - JOUR
DO - 10.1117/1.JBO.21.2.025006
UR - https://doi.org/10.1117%2F1.JBO.21.2.025006
TI - Computational model of bladder tissue based on its measured optical properties
T2 - Journal of Biomedical Optics
AU - Rafailov, Ilya E.
AU - Dremin, Victor V.
AU - Litvinova, Karina
AU - Dunaev, Andrey V.
AU - Socolovski, Sergey
AU - Rafailov, Edik
PY - 2016
DA - 2016/02/15 00:00:00
PB - SPIE
SP - 25006
IS - 2
VL - 21
SN - 1083-3668
SN - 1560-2281
ER -
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@article{2016_Rafailov,
author = {Ilya E. Rafailov and Victor V. Dremin and Karina Litvinova and Andrey V. Dunaev and Sergey Socolovski and Edik Rafailov},
title = {Computational model of bladder tissue based on its measured optical properties},
journal = {Journal of Biomedical Optics},
year = {2016},
volume = {21},
publisher = {SPIE},
month = {feb},
url = {https://doi.org/10.1117%2F1.JBO.21.2.025006},
number = {2},
pages = {25006},
doi = {10.1117/1.JBO.21.2.025006}
}
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MLA
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Rafailov, Ilya E., et al. “Computational model of bladder tissue based on its measured optical properties.” Journal of Biomedical Optics, vol. 21, no. 2, Feb. 2016, p. 25006. https://doi.org/10.1117%2F1.JBO.21.2.025006.