American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting, issue 38, pages 262-279

Global Epidemiology, Prevention, and Management of Hepatocellular Carcinoma

Mak Lung-Yi 1
Cruz Ramon Vania 1
Chinchilla-López Paulina 1
Torres Harrys A. 1
Loconte Noelle K 1
Rice John P. 1
Foxhall Lewis E. 1
Sturgis Erich M. 1
Merrill Janette K 1
Bailey Howard H. 1
Méndez-Sánchez Nahum 1
Yuen Man-Fung 1
Hwang Jessica P. 1
1
 
From the Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China; Liver Research Unit, Medica Sur Clinic and Foundation, Mexico City, Mexico; The University of Texas MD Anderson Cancer Center, Houston, TX; University of Wisconsin Carbone Cancer Center, Madison, WI; University of Wisconsin School of Medicine, Madison, WI; American Society of Clinical Oncology, Alexandria, VA.
Publication typeJournal Article
Publication date2018-05-08
General Medicine
Abstract

The incidence rate of hepatocellular carcinoma (HCC) is rising. It is one of the most common cancers worldwide and accounts for substantial morbidity and mortality. Chronic hepatitis B virus (HBV) infection, chronic hepatitis C virus (HCV) infection, and nonalcoholic fatty liver disease (NAFLD) are the most important etiologies of HCC, and effective screening and management strategies are crucial to reduce the HCC risk. For HBV, which accounts for the majority of HCC cases, most infections were acquired via perinatal and early horizontal transmission. Universal vaccination of newborns has led to a decline in HCC incidence compared with the pre-vaccination era. Effective antiviral therapies with nucleos(t)ide analogues or pegylated interferon reduced the incidence of HCC. For HCV, the emergence of effective direct-acting antiviral (DAA) agents has substantially improved cure rates; therefore all patients with HCV should be considered for DAA treatment. The most important obstacle in eliminating HCV is access to therapy. For NAFLD, the global incidence is increasing rapidly, thus its impact on HCC incidence may be explosive. Progression to HCC in NAFLD happens particularly in those with nonalcoholic steatohepatitis (NASH) and exacerbated by metabolic syndrome, or PNPLA3 gene polymorphism. Lifestyle changes are imperative while drug therapy has yet to demonstrate substantive protective effects on HCC prevention. For management of HCC, early diagnosis via imaging surveillance among persons with HCC risk factors remains the most important strategy to identify early-stage disease appropriate for resection or transplantation.

Citations by journals

1
2
3
4
5
Cancers
Cancers, 5, 3.5%
Cancers
5 publications, 3.5%
Frontiers in Oncology
Frontiers in Oncology, 4, 2.8%
Frontiers in Oncology
4 publications, 2.8%
Frontiers in Pharmacology
Frontiers in Pharmacology, 4, 2.8%
Frontiers in Pharmacology
4 publications, 2.8%
Molecules
Molecules, 3, 2.1%
Molecules
3 publications, 2.1%
Scientific Reports
Scientific Reports, 3, 2.1%
Scientific Reports
3 publications, 2.1%
Future Oncology
Future Oncology, 2, 1.4%
Future Oncology
2 publications, 1.4%
Experimental and Therapeutic Medicine
Experimental and Therapeutic Medicine, 2, 1.4%
Experimental and Therapeutic Medicine
2 publications, 1.4%
International Journal of Oncology
International Journal of Oncology, 2, 1.4%
International Journal of Oncology
2 publications, 1.4%
Medicine (United States)
Medicine (United States), 2, 1.4%
Medicine (United States)
2 publications, 1.4%
World Chinese Journal of Digestology, 2, 1.4%
World Chinese Journal of Digestology
2 publications, 1.4%
Hepatology International
Hepatology International, 2, 1.4%
Hepatology International
2 publications, 1.4%
Human Cell
Human Cell, 2, 1.4%
Human Cell
2 publications, 1.4%
Cancer Management and Research
Cancer Management and Research, 2, 1.4%
Cancer Management and Research
2 publications, 1.4%
Journal of Hepatocellular Carcinoma
Journal of Hepatocellular Carcinoma, 2, 1.4%
Journal of Hepatocellular Carcinoma
2 publications, 1.4%
Annals of Translational Medicine
Annals of Translational Medicine, 2, 1.4%
Annals of Translational Medicine
2 publications, 1.4%
Journal of Cancer Research and Clinical Oncology
Journal of Cancer Research and Clinical Oncology, 1, 0.7%
Journal of Cancer Research and Clinical Oncology
1 publication, 0.7%
Doklady Biochemistry and Biophysics
Doklady Biochemistry and Biophysics, 1, 0.7%
Doklady Biochemistry and Biophysics
1 publication, 0.7%
Frontiers in Public Health
Frontiers in Public Health, 1, 0.7%
Frontiers in Public Health
1 publication, 0.7%
Open Biomarkers Journal
Open Biomarkers Journal, 1, 0.7%
Open Biomarkers Journal
1 publication, 0.7%
Anti-Cancer Agents in Medicinal Chemistry
Anti-Cancer Agents in Medicinal Chemistry, 1, 0.7%
Anti-Cancer Agents in Medicinal Chemistry
1 publication, 0.7%
Liver Cancer
Liver Cancer, 1, 0.7%
Liver Cancer
1 publication, 0.7%
Bioscience Reports
Bioscience Reports, 1, 0.7%
Bioscience Reports
1 publication, 0.7%
Hepatology Communications
Hepatology Communications, 1, 0.7%
Hepatology Communications
1 publication, 0.7%
Nursing
Nursing, 1, 0.7%
Nursing
1 publication, 0.7%
Hepatology
Hepatology, 1, 0.7%
Hepatology
1 publication, 0.7%
Chinese Medical Journal
Chinese Medical Journal, 1, 0.7%
Chinese Medical Journal
1 publication, 0.7%
American Journal of Surgical Pathology
American Journal of Surgical Pathology, 1, 0.7%
American Journal of Surgical Pathology
1 publication, 0.7%
World Journal of Clinical Cases
World Journal of Clinical Cases, 1, 0.7%
World Journal of Clinical Cases
1 publication, 0.7%
World Journal of Gastroenterology
World Journal of Gastroenterology, 1, 0.7%
World Journal of Gastroenterology
1 publication, 0.7%
1
2
3
4
5

Citations by publishers

5
10
15
20
25
30
Springer Nature
Springer Nature, 26, 18.18%
Springer Nature
26 publications, 18.18%
Multidisciplinary Digital Publishing Institute (MDPI)
Multidisciplinary Digital Publishing Institute (MDPI), 15, 10.49%
Multidisciplinary Digital Publishing Institute (MDPI)
15 publications, 10.49%
Frontiers Media S.A.
Frontiers Media S.A., 14, 9.79%
Frontiers Media S.A.
14 publications, 9.79%
Wiley
Wiley, 12, 8.39%
Wiley
12 publications, 8.39%
Elsevier
Elsevier, 12, 8.39%
Elsevier
12 publications, 8.39%
Wolters Kluwer Health
Wolters Kluwer Health, 6, 4.2%
Wolters Kluwer Health
6 publications, 4.2%
AME Publishing Company
AME Publishing Company, 5, 3.5%
AME Publishing Company
5 publications, 3.5%
Spandidos Publications
Spandidos Publications, 4, 2.8%
Spandidos Publications
4 publications, 2.8%
Dove Medical Press
Dove Medical Press, 4, 2.8%
Dove Medical Press
4 publications, 2.8%
Baishideng Publishing Group
Baishideng Publishing Group, 3, 2.1%
Baishideng Publishing Group
3 publications, 2.1%
Taylor & Francis
Taylor & Francis, 3, 2.1%
Taylor & Francis
3 publications, 2.1%
Hindawi Limited
Hindawi Limited, 3, 2.1%
Hindawi Limited
3 publications, 2.1%
Pleiades Publishing
Pleiades Publishing, 2, 1.4%
Pleiades Publishing
2 publications, 1.4%
Bentham Science
Bentham Science, 2, 1.4%
Bentham Science
2 publications, 1.4%
Future Medicine
Future Medicine, 2, 1.4%
Future Medicine
2 publications, 1.4%
S. Karger AG
S. Karger AG, 2, 1.4%
S. Karger AG
2 publications, 1.4%
Shi Jie Wei Chang Bing Xue Za Zhi She, 2, 1.4%
Shi Jie Wei Chang Bing Xue Za Zhi She
2 publications, 1.4%
SAGE
SAGE, 2, 1.4%
SAGE
2 publications, 1.4%
Thieme
Thieme, 2, 1.4%
Thieme
2 publications, 1.4%
Public Library of Science (PLoS)
Public Library of Science (PLoS), 1, 0.7%
Public Library of Science (PLoS)
1 publication, 0.7%
Oxford University Press
Oxford University Press, 1, 0.7%
Oxford University Press
1 publication, 0.7%
Ob'edinennaya Redakcya OOO, 1, 0.7%
Ob'edinennaya Redakcya OOO
1 publication, 0.7%
Yonsei University, 1, 0.7%
Yonsei University
1 publication, 0.7%
Media Sphere Publishing Group
Media Sphere Publishing Group, 1, 0.7%
Media Sphere Publishing Group
1 publication, 0.7%
Turk Biyokimya Dernegi, 1, 0.7%
Turk Biyokimya Dernegi
1 publication, 0.7%
Scientific Centre for Family Health and Human Reproduction Problems
Scientific Centre for Family Health and Human Reproduction Problems, 1, 0.7%
Scientific Centre for Family Health and Human Reproduction Problems
1 publication, 0.7%
Grodno State Medical University
Grodno State Medical University, 1, 0.7%
Grodno State Medical University
1 publication, 0.7%
Jaypee Brothers Medical Publishing, 1, 0.7%
Jaypee Brothers Medical Publishing
1 publication, 0.7%
5
10
15
20
25
30
  • We do not take into account publications that without a DOI.
  • Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
  • Statistics recalculated weekly.
Metrics
Share
Cite this
GOST |
Cite this
GOST Copy
Mak L. et al. Global Epidemiology, Prevention, and Management of Hepatocellular Carcinoma // American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting. 2018. Vol. 38. pp. 262-279.
GOST all authors (up to 50) Copy
Mak L., Cruz Ramon V., Chinchilla-López P., Torres H. A., Loconte N. K., Rice J. P., Foxhall L. E., Sturgis E. M., Merrill J. K., Bailey H. H., Méndez-Sánchez N., Yuen M., Hwang J. P. Global Epidemiology, Prevention, and Management of Hepatocellular Carcinoma // American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting. 2018. Vol. 38. pp. 262-279.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1200/EDBK_200939
UR - https://doi.org/10.1200%2FEDBK_200939
TI - Global Epidemiology, Prevention, and Management of Hepatocellular Carcinoma
T2 - American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting
AU - Mak, Lung-Yi
AU - Cruz Ramon, Vania
AU - Chinchilla-López, Paulina
AU - Torres, Harrys A.
AU - Loconte, Noelle K
AU - Rice, John P.
AU - Foxhall, Lewis E.
AU - Sturgis, Erich M.
AU - Merrill, Janette K
AU - Bailey, Howard H.
AU - Méndez-Sánchez, Nahum
AU - Yuen, Man-Fung
AU - Hwang, Jessica P.
PY - 2018
DA - 2018/05/08 00:00:00
PB - American Society of Clinical Oncology (ASCO)
SP - 262-279
IS - 38
SN - 1548-8756
ER -
BibTex
Cite this
BibTex Copy
@article{2018_Mak
author = {Lung-Yi Mak and Vania Cruz Ramon and Paulina Chinchilla-López and Harrys A. Torres and Noelle K Loconte and John P. Rice and Lewis E. Foxhall and Erich M. Sturgis and Janette K Merrill and Howard H. Bailey and Nahum Méndez-Sánchez and Man-Fung Yuen and Jessica P. Hwang},
title = {Global Epidemiology, Prevention, and Management of Hepatocellular Carcinoma},
journal = {American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting},
year = {2018},
publisher = {American Society of Clinical Oncology (ASCO)},
month = {may},
url = {https://doi.org/10.1200%2FEDBK_200939},
number = {38},
pages = {262--279},
doi = {10.1200/EDBK_200939}
}
Found error?