Studies on Nitrofuran Derivatives. IV. Synthesis of 2- or 4-[2-(5-Nitro-2-furyl) vinyl] pyrimidine Derivatives
1
Research Laboratory, Dainippon Pharmaceutical Co., Ltd., Research Laboratory, Dainippon Pharmaceutical Co., Ltd., Research Laboratory, Dainippon Pharmaceutical Co., Ltd., Research Laboratory, Dainippon Pharmaceutical Co., Ltd.
Publication type: Journal Article
Publication date: 2011-12-08
scimago Q3
wos Q3
SJR: 0.349
CiteScore: 2.7
Impact factor: 1.3
ISSN: 00092363, 13475223
PubMed ID:
5864700
General Chemistry
Drug Discovery
General Medicine
Abstract
To test the antibacterial activity, 2- or 4-[2-(5-nitro-2-furyl) vinyl] pyrimidines were synthesized by the condensation of 5-nitro-2-furaldehyde (Va) with the active methyl group of pyrimidines. It has been found that Va predominantly condensed with the 4-methyl group of 2, 4-dimethylpyrimidine and in the reaction of Va with 2, 4-dimethylpyrimidine containing a functional group in the 6-position, the active hydrogen reactivity between the 2-methyl group and 4-methyl group is affected by the presence of group in the 6-position : in 2, 4-dimethylpyrimidines substituted by the hydroxy, amino and alkoxy group in the 6-position, the 2-methyl group was founded to be more active, while in the ones substituted by the acetamido, dimethylamino and chloro group, the 4-methyl group was more reactive.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
|
|
|
Cumulative Index of Heterocyclic Systems
2 publications, 66.67%
|
|
|
Chemistry of Heterocyclic Compounds
1 publication, 33.33%
|
|
|
1
2
|
Publishers
|
1
2
|
|
|
Wiley
2 publications, 66.67%
|
|
|
Springer Nature
1 publication, 33.33%
|
|
|
1
2
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
3
Total citations:
3
Citations from 2024:
0
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Fujita A. et al. Studies on Nitrofuran Derivatives. IV. Synthesis of 2- or 4-[2-(5-Nitro-2-furyl) vinyl] pyrimidine Derivatives // Chemical and Pharmaceutical Bulletin. 2011. Vol. 13. No. 10. pp. 1183-1193.
GOST all authors (up to 50)
Copy
Fujita A., Yamamoto T., Minami S., Takamatsu H. Studies on Nitrofuran Derivatives. IV. Synthesis of 2- or 4-[2-(5-Nitro-2-furyl) vinyl] pyrimidine Derivatives // Chemical and Pharmaceutical Bulletin. 2011. Vol. 13. No. 10. pp. 1183-1193.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1248/cpb.13.1183
UR - https://doi.org/10.1248/cpb.13.1183
TI - Studies on Nitrofuran Derivatives. IV. Synthesis of 2- or 4-[2-(5-Nitro-2-furyl) vinyl] pyrimidine Derivatives
T2 - Chemical and Pharmaceutical Bulletin
AU - Fujita, Akio
AU - Yamamoto, Tadatsugu
AU - Minami, Shinsaku
AU - Takamatsu, Hideji
PY - 2011
DA - 2011/12/08
PB - Pharmaceutical Society of Japan
SP - 1183-1193
IS - 10
VL - 13
PMID - 5864700
SN - 0009-2363
SN - 1347-5223
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2011_Fujita,
author = {Akio Fujita and Tadatsugu Yamamoto and Shinsaku Minami and Hideji Takamatsu},
title = {Studies on Nitrofuran Derivatives. IV. Synthesis of 2- or 4-[2-(5-Nitro-2-furyl) vinyl] pyrimidine Derivatives},
journal = {Chemical and Pharmaceutical Bulletin},
year = {2011},
volume = {13},
publisher = {Pharmaceutical Society of Japan},
month = {dec},
url = {https://doi.org/10.1248/cpb.13.1183},
number = {10},
pages = {1183--1193},
doi = {10.1248/cpb.13.1183}
}
Cite this
MLA
Copy
Fujita, Akio, et al. “Studies on Nitrofuran Derivatives. IV. Synthesis of 2- or 4-[2-(5-Nitro-2-furyl) vinyl] pyrimidine Derivatives.” Chemical and Pharmaceutical Bulletin, vol. 13, no. 10, Dec. 2011, pp. 1183-1193. https://doi.org/10.1248/cpb.13.1183.