Open Access
Open access
volume 8 issue 11 pages 1471

Quantitative super-resolution solid immersion microscopy via refractive index profile reconstruction

N V Chernomyrdin 1, 2, 3
A.A. Gavdush 1
G R Musina 1
G M Katyba 1, 5
A M Khorokhorov 2
I E Spektor 1
Valery V. Tuchin 6, 7, 8, 9
Publication typeJournal Article
Publication date2021-11-11
scimago Q1
wos Q1
SJR3.080
CiteScore17.5
Impact factor8.5
ISSN23342536
Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Abstract

Solid Immersion (SI) microscopy is a modern imaging modality that overcomes the Abbe diffraction limit and offers novel applications in various branches of visible, infrared, terahertz, and millimeter-wave optics. Despite the widespread use, SI microscopy usually results in qualitative imaging. Indeed, it presents only the raw distributions (in the image plane) of the backscattered field intensity, while unlocking the information about the physical properties of an imaged object, such as its complex refractive index (RI) distribution, requires resolving the inverse problem and remains a daunting task. In this paper, a method for resolving the SI microscopy inverse problem is developed, capable of reconstructing the RI distribution at the object imaging plane with subwavelength spatial resolution, while performing only intensity measurements. The sample RI is retrieved via minimization of the error function that characterizes discrepancy between the experimental data and the predictions of analytical model. This model incorporates all the key features of the electromagnetic-wave interaction with the SI lens and an imaged object, including contributions of the evanescent and ordinary-reflected waves, as well as effects of light polarization and wide beam aperture. The model is verified numerically, using the finite-element frequency-domain method, and experimentally, using the in-house reflection-mode continuous-wave terahertz SI microscope. Spatial distributions of the terahertz RIs of different low-absorbing optical materials and highly absorbing biological objects were studied and compared to a priori known data to demonstrate the potential of the novel SI microscopy modality. Given the linear nature of the Maxwell’s equations, the developed method can be applied for subwavelength-resolution SI microscopy at other spectral ranges.

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GOST Copy
Chernomyrdin N. V. et al. Quantitative super-resolution solid immersion microscopy via refractive index profile reconstruction // Optica. 2021. Vol. 8. No. 11. p. 1471.
GOST all authors (up to 50) Copy
Chernomyrdin N. V., Skorobogatiy M., Gavdush A., Musina G. R., Katyba G. M., Komandin G. A., Khorokhorov A. M., Spektor I. E., Tuchin V. V., Zaytsev K. I. Quantitative super-resolution solid immersion microscopy via refractive index profile reconstruction // Optica. 2021. Vol. 8. No. 11. p. 1471.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1364/OPTICA.439286
UR - https://opg.optica.org/abstract.cfm?URI=optica-8-11-1471
TI - Quantitative super-resolution solid immersion microscopy via refractive index profile reconstruction
T2 - Optica
AU - Chernomyrdin, N V
AU - Skorobogatiy, M.
AU - Gavdush, A.A.
AU - Musina, G R
AU - Katyba, G M
AU - Komandin, Gennady A.
AU - Khorokhorov, A M
AU - Spektor, I E
AU - Tuchin, Valery V.
AU - Zaytsev, Kirill I.
PY - 2021
DA - 2021/11/11
PB - Optica Publishing Group
SP - 1471
IS - 11
VL - 8
SN - 2334-2536
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Chernomyrdin,
author = {N V Chernomyrdin and M. Skorobogatiy and A.A. Gavdush and G R Musina and G M Katyba and Gennady A. Komandin and A M Khorokhorov and I E Spektor and Valery V. Tuchin and Kirill I. Zaytsev},
title = {Quantitative super-resolution solid immersion microscopy via refractive index profile reconstruction},
journal = {Optica},
year = {2021},
volume = {8},
publisher = {Optica Publishing Group},
month = {nov},
url = {https://opg.optica.org/abstract.cfm?URI=optica-8-11-1471},
number = {11},
pages = {1471},
doi = {10.1364/OPTICA.439286}
}
MLA
Cite this
MLA Copy
Chernomyrdin, N. V., et al. “Quantitative super-resolution solid immersion microscopy via refractive index profile reconstruction.” Optica, vol. 8, no. 11, Nov. 2021, p. 1471. https://opg.optica.org/abstract.cfm?URI=optica-8-11-1471.