Three-dimensional model of biomatrix as a method of studying blood vessels and nerve growth in tissue engineering structures
Publication type: Journal Article
Publication date: 2016-05-01
scimago Q4
wos Q4
SJR: 0.153
CiteScore: 1.1
Impact factor: 0.5
ISSN: 00271314, 19350260
General Chemistry
Abstract
The method involves isolating and culturing ex vivo cultures of mouse dorsal root ganglia and abdominal aorta in a three-dimensional gel (Matrigel). Unlike other explant cultures, this technique allows to study the physiological and biochemical processes in the tissue explants of dorsal root ganglia and abdominal aorta in three-dimensional space but in contrast to a two-dimensional adhesive culture. Administration of the tested substances to the Matrigel allows analyzing their effects on the growth of blood vessels and neurites from the explants for 21 days. The developed method can be applied in modern cardiological and neurobiological research and explores how new therapeutic agents can accelerate the regeneration of blood vessels and nerves.
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Semina E. V. et al. Three-dimensional model of biomatrix as a method of studying blood vessels and nerve growth in tissue engineering structures // Moscow University Chemistry Bulletin. 2016. Vol. 71. No. 3. pp. 172-177.
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Semina E. V., Rubina K. A., Sysoeva V. Yu., Stepanova V. V., Tkachuk V. A. Three-dimensional model of biomatrix as a method of studying blood vessels and nerve growth in tissue engineering structures // Moscow University Chemistry Bulletin. 2016. Vol. 71. No. 3. pp. 172-177.
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RIS
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TY - JOUR
DO - 10.3103/s0027131416030081
UR - https://doi.org/10.3103/s0027131416030081
TI - Three-dimensional model of biomatrix as a method of studying blood vessels and nerve growth in tissue engineering structures
T2 - Moscow University Chemistry Bulletin
AU - Semina, E V
AU - Rubina, K A
AU - Sysoeva, V Yu
AU - Stepanova, V V
AU - Tkachuk, V. A.
PY - 2016
DA - 2016/05/01
PB - Pleiades Publishing
SP - 172-177
IS - 3
VL - 71
SN - 0027-1314
SN - 1935-0260
ER -
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BibTex (up to 50 authors)
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@article{2016_Semina,
author = {E V Semina and K A Rubina and V Yu Sysoeva and V V Stepanova and V. A. Tkachuk},
title = {Three-dimensional model of biomatrix as a method of studying blood vessels and nerve growth in tissue engineering structures},
journal = {Moscow University Chemistry Bulletin},
year = {2016},
volume = {71},
publisher = {Pleiades Publishing},
month = {may},
url = {https://doi.org/10.3103/s0027131416030081},
number = {3},
pages = {172--177},
doi = {10.3103/s0027131416030081}
}
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MLA
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Semina, E. V., et al. “Three-dimensional model of biomatrix as a method of studying blood vessels and nerve growth in tissue engineering structures.” Moscow University Chemistry Bulletin, vol. 71, no. 3, May. 2016, pp. 172-177. https://doi.org/10.3103/s0027131416030081.