Open Access
Acta Naturae, volume 12, issue 1, pages 84-88
The telomeric Cdc13 protein from yeast hansenula polymorpha
Publication type: Journal Article
Publication date: 2020-04-16
PubMed ID:
32477602
Biochemistry
Molecular Biology
Molecular Medicine
Biotechnology
Abstract
Telomeres are special structures at the ends of chromosomes that play an important role in the protection of the genetic material. Telomere composition is very diverse; noticeable differences can often be observed even among closely related species. Here, we identify the homolog of telomeric protein Cdc13 in the thermotolerant yeast Hansenula polymorpha. We show that it can specifically bind single-stranded telomeric DNA, as well as interact with the Stn1 protein. In addition, we have uncovered an interaction between Cdc13 and TERT (one of the core components of the telomerase complex), which suggests that Cdc13 is potentially involved in telomerase recruitment to telomeres in H. polymorpha.
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eLife
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eLife
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eLife Sciences Publications
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eLife Sciences Publications
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Malyavko A. N., Dontsova O. A. The telomeric Cdc13 protein from yeast hansenula polymorpha // Acta Naturae. 2020. Vol. 12. No. 1. pp. 84-88.
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Malyavko A. N., Dontsova O. A. The telomeric Cdc13 protein from yeast hansenula polymorpha // Acta Naturae. 2020. Vol. 12. No. 1. pp. 84-88.
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TY - JOUR
DO - 10.32607/actanaturae.10944
UR - https://doi.org/10.32607%2Factanaturae.10944
TI - The telomeric Cdc13 protein from yeast hansenula polymorpha
T2 - Acta Naturae
AU - Malyavko, Alexander N
AU - Dontsova, Olga A.
PY - 2020
DA - 2020/04/16 00:00:00
PB - Acta Naturae Ltd
SP - 84-88
IS - 1
VL - 12
PMID - 32477602
SN - 2075-8251
SN - 2075-8243
ER -
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BibTex
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@article{2020_Malyavko,
author = {Alexander N Malyavko and Olga A. Dontsova},
title = {The telomeric Cdc13 protein from yeast hansenula polymorpha},
journal = {Acta Naturae},
year = {2020},
volume = {12},
publisher = {Acta Naturae Ltd},
month = {apr},
url = {https://doi.org/10.32607%2Factanaturae.10944},
number = {1},
pages = {84--88},
doi = {10.32607/actanaturae.10944}
}
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Malyavko, Alexander N., and Olga A. Dontsova. “The telomeric Cdc13 protein from yeast hansenula polymorpha.” Acta Naturae, vol. 12, no. 1, Apr. 2020, pp. 84-88. https://doi.org/10.32607%2Factanaturae.10944.
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