Open Access

Frontiers in Microbiology, volume 9

Diversity, novelty, and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi, China

Jiang Zhong-Ke ¹

Tuo Li ²

Huang Da-Lin ³

Osterman Ilya A. ^{4, 5}

Tyurin Anton P ^{6, 7}

Liu Shao-Wei ¹

Lukyanov Dmitry A ⁴

Sergiev Petr V. ^{4, 5}

Dontsova Olga A. ^{4, 5}

Korshun Vladimir A ^{6, 7}

Li Fei-Na ¹

Sun Cheng-Hang ¹

Hide authors affiliations Show authors affiliations: 7 affiliations

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, China |

Research Center for Medicine and Biology, Zunyi Medical University, China |

College of Basic Medical Sciences, Guilin Medical University, China |

⁴

Department of Chemistry, A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Russia |

⁵

Skolkovo Institute of Science and Technology, Russia |

⁶

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russia |

⁷

Gause Institute of New Antibiotics, Russia |

Publication type: Journal Article

Publication date: 2018-05-04

Frontiers Media S.A.

Journal: Frontiers in Microbiology

Quartile SCImago

Quartile WOS

Impact factor: 5.2

ISSN: 1664302X

DOI: 10.3389/fmicb.2018.00868

Copy DOI

PubMed ID: 29780376

Microbiology (medical)

Microbiology

Abstract

Endophytic actinobacteria are one of the important pharmaceutical resources and well known for producing different types of bioactive substances. Nevertheless, detection of the novelty, diversity and bioactivity on endophytic actinobacteria isolated from mangrove plants are scarce. In this study, five different mangrove plants, Avicennia marina, Aegiceras corniculatum, Kandelia obovota, Bruguiera gymnorrhiza and Thespesia populnea,were collected from Beilun Estuary National Nature Reserve in Guangxi Zhuang Autonomous Region, China. One-hundred and one endophytic actinobacteria strains were recovered by culture-based approaches. They distributed in 7 orders，15 families and 28 genera including Streptomyces, Curtobacterium, Mycobacterium, Micrococcus, Brevibacterium, Kocuria, Nocardioides, Kineococcus, Kytococcus, Marmoricola, Microbacterium, Micromonospora, Actinoplanes, Agrococcus, Amnibacterium, Brachybacterium, Citricoccus, Dermacoccus, Glutamicibacter, Gordonia, Isoptericola, Janibacter, Leucobacter, Nocardia, Nocardiopsis, Pseudokineococcus, Sanguibacter, and Verrucosispora. Among them, seven strains were potentially new species of genera Nocardioides, Streptomyces, Amnibacterium, Marmoricola and Mycobacterium. Above all, strain 8BXZ-J1 has already been characterized as a new species of the genus Marmoricola. Sixty three out of 101 strains were chosen to screen antibacterial activities by paper-disc diffusion method and inhibitors of ribosome and DNA biosynthesis by means of a double fluorescent protein reporter. Thirty one strains exhibited positive results in at least one antibacterial assay. Notably, strain 8BXZ-J1 and three other potential novel species, 7BMP-1, 5BQP-J3 and 1BXZ-J1, all showed antibacterial bioactivity. In addition, twenty one strains showed inhibitory activities against at least one “ESKAPE” resistant pathogens. We also found that Streptomyces strains 2BBP-J2 and 1BBP-1 produce bioactive compound with inhibitory activity on protein biosynthesis as result of translation stalling. Meanwhile, Streptomyces strain 3BQP-1 produces bioactive compound inducing SOS-response due to DNA damage. In conclusion, this study proved mangrove plants harbored a high diversity of cultivable endophytic actinobacteria, which can be a promising source for discovery of novel species and bioactive compounds.

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Citations by journals

	1 2 3 4 5 6 7
Frontiers in Microbiology	Frontiers in Microbiology, 7, 12.07% Frontiers in Microbiology 7 publications, 12.07%
Microorganisms	Microorganisms, 3, 5.17% Microorganisms 3 publications, 5.17%
Marine Drugs	Marine Drugs, 2, 3.45% Marine Drugs 2 publications, 3.45%
Frontiers in Marine Science	Frontiers in Marine Science, 2, 3.45% Frontiers in Marine Science 2 publications, 3.45%
Journal of Applied Microbiology	Journal of Applied Microbiology, 2, 3.45% Journal of Applied Microbiology 2 publications, 3.45%
Molecular Plant-Microbe Interactions	Molecular Plant-Microbe Interactions, 2, 3.45% Molecular Plant-Microbe Interactions 2 publications, 3.45%
Antibiotics	Antibiotics, 1, 1.72% Antibiotics 1 publication, 1.72%
Journal of Pharmaceutical Analysis	Journal of Pharmaceutical Analysis, 1, 1.72% Journal of Pharmaceutical Analysis 1 publication, 1.72%
Journal of Asian Natural Products Research	Journal of Asian Natural Products Research, 1, 1.72% Journal of Asian Natural Products Research 1 publication, 1.72%
PeerJ	PeerJ, 1, 1.72% PeerJ 1 publication, 1.72%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 1, 1.72% International Journal of Molecular Sciences 1 publication, 1.72%
Frontiers in Plant Science	Frontiers in Plant Science, 1, 1.72% Frontiers in Plant Science 1 publication, 1.72%
Journal of Genetic Engineering and Biotechnology	Journal of Genetic Engineering and Biotechnology, 1, 1.72% Journal of Genetic Engineering and Biotechnology 1 publication, 1.72%
Environmental Microbiomes	Environmental Microbiomes, 1, 1.72% Environmental Microbiomes 1 publication, 1.72%
Journal of Microbiology	Journal of Microbiology, 1, 1.72% Journal of Microbiology 1 publication, 1.72%
Antonie van Leeuwenhoek	Antonie van Leeuwenhoek, 1, 1.72% Antonie van Leeuwenhoek 1 publication, 1.72%
Annals of Microbiology	Annals of Microbiology, 1, 1.72% Annals of Microbiology 1 publication, 1.72%
Journal of Soil Science and Plant Nutrition	Journal of Soil Science and Plant Nutrition, 1, 1.72% Journal of Soil Science and Plant Nutrition 1 publication, 1.72%
Brazilian Journal of Microbiology	Brazilian Journal of Microbiology, 1, 1.72% Brazilian Journal of Microbiology 1 publication, 1.72%
Die Naturwissenschaften	Die Naturwissenschaften, 1, 1.72% Die Naturwissenschaften 1 publication, 1.72%
Current Microbiology	Current Microbiology, 1, 1.72% Current Microbiology 1 publication, 1.72%
Life	Life, 1, 1.72% Life 1 publication, 1.72%
Environmental Pollution	Environmental Pollution, 1, 1.72% Environmental Pollution 1 publication, 1.72%
Microbiological Research	Microbiological Research, 1, 1.72% Microbiological Research 1 publication, 1.72%
International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 1, 1.72% International Journal of Biological Macromolecules 1 publication, 1.72%
MicrobiologyOpen	MicrobiologyOpen, 1, 1.72% MicrobiologyOpen 1 publication, 1.72%
Ecology	Ecology, 1, 1.72% Ecology 1 publication, 1.72%
New Journal of Chemistry	New Journal of Chemistry, 1, 1.72% New Journal of Chemistry 1 publication, 1.72%
Russian Journal of Marine Biology	Russian Journal of Marine Biology, 1, 1.72% Russian Journal of Marine Biology 1 publication, 1.72%
	1 2 3 4 5 6 7

Citations by publishers

	2 4 6 8 10 12
Springer Nature	Springer Nature, 11, 18.97% Springer Nature 11 publications, 18.97%
Frontiers Media S.A.	Frontiers Media S.A., 10, 17.24% Frontiers Media S.A. 10 publications, 17.24%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 9, 15.52% Multidisciplinary Digital Publishing Institute (MDPI) 9 publications, 15.52%
Wiley	Wiley, 4, 6.9% Wiley 4 publications, 6.9%
Elsevier	Elsevier, 3, 5.17% Elsevier 3 publications, 5.17%
American Phytopathological Society	American Phytopathological Society, 2, 3.45% American Phytopathological Society 2 publications, 3.45%
Xi'an Jiaotong University	Xi'an Jiaotong University, 1, 1.72% Xi'an Jiaotong University 1 publication, 1.72%
Taylor & Francis	Taylor & Francis, 1, 1.72% Taylor & Francis 1 publication, 1.72%
PeerJ	PeerJ, 1, 1.72% PeerJ 1 publication, 1.72%
Han-Gug Misaengmul Hag-hoe/The Microbiological Society of Korea	Han-Gug Misaengmul Hag-hoe/The Microbiological Society of Korea, 1, 1.72% Han-Gug Misaengmul Hag-hoe/The Microbiological Society of Korea 1 publication, 1.72%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 1.72% Royal Society of Chemistry (RSC) 1 publication, 1.72%
Pleiades Publishing	Pleiades Publishing, 1, 1.72% Pleiades Publishing 1 publication, 1.72%
Academic Journals	Academic Journals, 1, 1.72% Academic Journals 1 publication, 1.72%
Hindawi Limited	Hindawi Limited, 1, 1.72% Hindawi Limited 1 publication, 1.72%
	2 4 6 8 10 12

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Jiang Z. et al. Diversity, novelty, and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi, China // Frontiers in Microbiology. 2018. Vol. 9.

GOST all authors (up to 50) Copy

Jiang Z., Tuo Li, Huang D., Osterman I. A., Tyurin A. P., Liu S., Lukyanov D. A., Sergiev P. V., Dontsova O. A., Korshun V. A., Li F., Sun C. Diversity, novelty, and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi, China // Frontiers in Microbiology. 2018. Vol. 9.

RIS |

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RIS Copy

TY - JOUR

DO - 10.3389/fmicb.2018.00868

UR - https://doi.org/10.3389%2Ffmicb.2018.00868

TI - Diversity, novelty, and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi, China

T2 - Frontiers in Microbiology

AU - Jiang, Zhong-Ke

AU - Tuo Li

AU - Huang, Da-Lin

AU - Osterman, Ilya A.

AU - Tyurin, Anton P

AU - Liu, Shao-Wei

AU - Lukyanov, Dmitry A

AU - Sergiev, Petr V.

AU - Dontsova, Olga A.

AU - Korshun, Vladimir A

AU - Li, Fei-Na

AU - Sun, Cheng-Hang

PY - 2018

DA - 2018/05/04 00:00:00

PB - Frontiers Media S.A.

VL - 9

PMID - 29780376

SN - 1664-302X

ER -

BibTex

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@article{2018_Jiang,

author = {Zhong-Ke Jiang and Tuo Li and Da-Lin Huang and Ilya A. Osterman and Anton P Tyurin and Shao-Wei Liu and Dmitry A Lukyanov and Petr V. Sergiev and Olga A. Dontsova and Vladimir A Korshun and Fei-Na Li and Cheng-Hang Sun},

title = {Diversity, novelty, and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi, China},

journal = {Frontiers in Microbiology},

year = {2018},

volume = {9},

publisher = {Frontiers Media S.A.},

month = {may},

url = {https://doi.org/10.3389%2Ffmicb.2018.00868},

doi = {10.3389/fmicb.2018.00868}

}

Found error?

Publisher

Frontiers Media S.A.

Journal

Frontiers in Microbiology

Quartile SCImago

Quartile WOS

Impact factor

5.2

ISSN

1664302X (Print)

Labs

Laboratory of Nucleoprotein Chemistry, Department of Chemistry of Natural Compounds, Faculty of Chemistry

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