Open Access
Biomolecules, volume 11, issue 11, pages 1665
LncRNAs: Novel Biomarkers for Pancreatic Cancer
3
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo 0608638, Japan
|
Publication type: Journal Article
Publication date: 2021-11-10
PubMed ID:
34827663
Biochemistry
Molecular Biology
Abstract
Pancreatic cancer is one of the most deadly neoplasms and the seventh major cause of cancer-related deaths among both males and females. This cancer has a poor prognosis due to the lack of appropriate methods for early detection of cancer. Long non-coding RNAs (lncRNAs) have been recently found to influence the progression and initiation of pancreatic cancer. MACC1-AS1, LINC00976, LINC00462, LINC01559, HOXA-AS2, LINC00152, TP73-AS1, XIST, SNHG12, LUCAT1, and UCA1 are among the oncogenic lncRNAs in pancreatic cancer. On the other hand, LINC01111, LINC01963, DGCR5, MEG3, GAS5, and LINC00261 are among tumor suppressor lncRNAs in this tissue. In the current review, we summarize the roles of these two classes of lncRNAs in pancreatic cancer and discuss their potential as attractive diagnostic and prognostic biomarkers for pancreatic cancer. We also identified that the low expression of MEG3, LINC01963, and LINC00261 and the high expression of MACC1-AS1, LINC00462, LINC01559, and UCA1 were significantly correlated with worse survival in pancreatic cancer patients. Further research on these lncRNAs will provide new clues that could potentially improve the early diagnosis, prognostic prediction, and personalized treatments of patients with pancreatic cancer.
Citations by journals
1
2
3
4
5
6
|
|
Pathology Research and Practice
|
Pathology Research and Practice
6 publications, 16.22%
|
Frontiers in Cell and Developmental Biology
|
Frontiers in Cell and Developmental Biology
3 publications, 8.11%
|
Biomedicine and Pharmacotherapy
|
Biomedicine and Pharmacotherapy
3 publications, 8.11%
|
Medicine (United States)
|
Medicine (United States)
2 publications, 5.41%
|
Doklady Biochemistry and Biophysics
|
Doklady Biochemistry and Biophysics
1 publication, 2.7%
|
World Journal of Gastroenterology
|
World Journal of Gastroenterology
1 publication, 2.7%
|
Cells
|
Cells
1 publication, 2.7%
|
Non-coding RNA
|
Non-coding RNA
1 publication, 2.7%
|
Cell Death Discovery
|
Cell Death Discovery
1 publication, 2.7%
|
Seminars in Cancer Biology
|
Seminars in Cancer Biology
1 publication, 2.7%
|
Drug Discovery Today
|
Drug Discovery Today
1 publication, 2.7%
|
Translational Oncology
|
Translational Oncology, 1, 2.7%
Translational Oncology
1 publication, 2.7%
|
International Journal of Biological Macromolecules
|
International Journal of Biological Macromolecules
1 publication, 2.7%
|
Journal of Immunology Research
|
Journal of Immunology Research
1 publication, 2.7%
|
Cancers
|
Cancers
1 publication, 2.7%
|
Journal of Gastrointestinal Oncology
|
Journal of Gastrointestinal Oncology
1 publication, 2.7%
|
Scientific Reports
|
Scientific Reports
1 publication, 2.7%
|
Advanced Therapeutics
|
Advanced Therapeutics
1 publication, 2.7%
|
Archives of Biochemistry and Biophysics
|
Archives of Biochemistry and Biophysics
1 publication, 2.7%
|
Phytomedicine
|
Phytomedicine
1 publication, 2.7%
|
Pharmaceutics
|
Pharmaceutics
1 publication, 2.7%
|
Nanoscale
|
Nanoscale
1 publication, 2.7%
|
Journal of International Medical Research
|
Journal of International Medical Research
1 publication, 2.7%
|
1
2
3
4
5
6
|
Citations by publishers
2
4
6
8
10
12
14
|
|
Elsevier
|
Elsevier
14 publications, 37.84%
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
4 publications, 10.81%
|
Frontiers Media S.A.
|
Frontiers Media S.A.
3 publications, 8.11%
|
Springer Nature
|
Springer Nature
2 publications, 5.41%
|
Wolters Kluwer Health
|
Wolters Kluwer Health
2 publications, 5.41%
|
Pleiades Publishing
|
Pleiades Publishing
1 publication, 2.7%
|
Baishideng Publishing Group
|
Baishideng Publishing Group
1 publication, 2.7%
|
Neoplasia Press
|
Neoplasia Press, 1, 2.7%
Neoplasia Press
1 publication, 2.7%
|
Hindawi Limited
|
Hindawi Limited
1 publication, 2.7%
|
AME Publishing Company
|
AME Publishing Company
1 publication, 2.7%
|
Wiley
|
Wiley
1 publication, 2.7%
|
Royal Society of Chemistry (RSC)
|
Royal Society of Chemistry (RSC)
1 publication, 2.7%
|
SAGE
|
SAGE
1 publication, 2.7%
|
2
4
6
8
10
12
14
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2022,2023,2024],"ids":[0,0,0],"codes":[0,0,0],"imageUrls":["","",""],"datasets":[{"label":"Citations number","data":[12,19,6],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":["32.43","51.35","16.22"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Pathology Research and Practice","Frontiers in Cell and Developmental Biology","Biomedicine and Pharmacotherapy","Medicine (United States)","Doklady Biochemistry and Biophysics","World Journal of Gastroenterology","Cells","Non-coding RNA","Cell Death Discovery","Seminars in Cancer Biology","Drug Discovery Today","Translational Oncology","International Journal of Biological Macromolecules","Journal of Immunology Research","Cancers","Journal of Gastrointestinal Oncology","Scientific Reports","Advanced Therapeutics","Archives of Biochemistry and Biophysics","Phytomedicine","Pharmaceutics","Nanoscale","Journal of International Medical Research"],"ids":[2120,12128,23951,19945,3773,19469,25293,18908,10757,19338,23042,15165,23035,1960,22471,4410,13767,25457,15591,5424,4502,228,22431],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/bKOjgSt9mSGUD9fzKZyqcKSIgDCDSMd1ZWjJOZzx_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/PYBAYQjpFdxPQPRGY3kU5Xzbu0W7K7umVNk0TY9i_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp"],"datasets":[{"label":"","data":[6,3,3,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[16.22,8.11,8.11,5.41,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","Frontiers Media S.A.","Springer Nature","Wolters Kluwer Health","Pleiades Publishing","Baishideng Publishing Group","Neoplasia Press","Hindawi Limited","AME Publishing Company","Wiley","Royal Society of Chemistry (RSC)","SAGE"],"ids":[17,202,208,8,32,101,7719,4513,6921,1566,11,123,31],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/bKOjgSt9mSGUD9fzKZyqcKSIgDCDSMd1ZWjJOZzx_medium.webp","","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/PYBAYQjpFdxPQPRGY3kU5Xzbu0W7K7umVNk0TY9i_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp"],"datasets":[{"label":"","data":[14,4,3,2,2,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[37.84,10.81,8.11,5.41,5.41,2.7,2.7,2.7,2.7,2.7,2.7,2.7,2.7],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Ghafouri-Fard S. et al. LncRNAs: Novel Biomarkers for Pancreatic Cancer // Biomolecules. 2021. Vol. 11. No. 11. p. 1665.
GOST all authors (up to 50)
Copy
Ghafouri-Fard S., Fathi M., Zhai T., Taheri M., Dong P. LncRNAs: Novel Biomarkers for Pancreatic Cancer // Biomolecules. 2021. Vol. 11. No. 11. p. 1665.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/biom11111665
UR - https://doi.org/10.3390%2Fbiom11111665
TI - LncRNAs: Novel Biomarkers for Pancreatic Cancer
T2 - Biomolecules
AU - Fathi, Mohadeseh
AU - Ghafouri-Fard, Soudeh
AU - Zhai, Tianyue
AU - Taheri, Mohammad
AU - Dong, Peixin
PY - 2021
DA - 2021/11/10 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 1665
IS - 11
VL - 11
PMID - 34827663
SN - 2218-273X
ER -
Cite this
BibTex
Copy
@article{2021_Ghafouri-Fard
author = {Mohadeseh Fathi and Soudeh Ghafouri-Fard and Tianyue Zhai and Mohammad Taheri and Peixin Dong},
title = {LncRNAs: Novel Biomarkers for Pancreatic Cancer},
journal = {Biomolecules},
year = {2021},
volume = {11},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {nov},
url = {https://doi.org/10.3390%2Fbiom11111665},
number = {11},
pages = {1665},
doi = {10.3390/biom11111665}
}
Cite this
MLA
Copy
Ghafouri-Fard, Soudeh, et al. “LncRNAs: Novel Biomarkers for Pancreatic Cancer.” Biomolecules, vol. 11, no. 11, Nov. 2021, p. 1665. https://doi.org/10.3390%2Fbiom11111665.