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International Journal of Molecular Sciences, volume 23, issue 19, pages 11134

Magneto-Mechanical Approach in Biomedicine: Benefits, Challenges, and Future Perspectives

Nikitin Aleksey A ^{1, 2}

Ivanova Anna V. ²

Semkina Alevtina S. ²

Lazareva Polina A ²

Abakumov Maxim A. ²

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Laboratory of Biomedical Nanomaterials, National University of Science and Technology (MISIS), 119049 Moscow, Russia |

Department of Medical Nanobiotechnology, N.I. Pirogov Russian National Research Medical University, 117997 Moscow, Russia |

Publication type: Journal Article

Publication date: 2022-09-22

Multidisciplinary Digital Publishing Institute (MDPI)

Journal: International Journal of Molecular Sciences

Quartile SCImago

Quartile WOS

Impact factor: 5.6

ISSN: 16616596, 14220067

DOI: 10.3390/ijms231911134

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PubMed ID: 36232435

Catalysis

Organic Chemistry

Inorganic Chemistry

Physical and Theoretical Chemistry

Computer Science Applications

Spectroscopy

Molecular Biology

General Medicine

Abstract

The magneto-mechanical approach is a powerful technique used in many different applications in biomedicine, including remote control enzyme activity, cell receptors, cancer-selective treatments, mechanically-activated drug releases, etc. This approach is based on the use of a combination of magnetic nanoparticles and external magnetic fields that have led to the movement of such nanoparticles with torques and forces (enough to change the conformation of biomolecules or even break weak chemical bonds). However, despite many theoretical and experimental works on this topic, it is difficult to predict the magneto-mechanical effects in each particular case, while the important results are scattered and often cannot be translated to other experiments. The main reason is that the magneto-mechanical effect is extremely sensitive to changes in any parameter of magnetic nanoparticles and the environment and changes in the parameters of the applied magnetic field. Thus, in this review, we (1) summarize and propose a simplified theoretical explanation of the main factors affecting the efficiency of the magneto-mechanical approach; (2) discuss the nature of the MNP-mediated mechanical forces and their order of magnitude; (3) show some of the main applications of the magneto-mechanical approach in the control over the properties of biological systems.

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Citations by journals

	1 2
Magnetochemistry	Magnetochemistry, 2, 20% Magnetochemistry 2 publications, 20%
Journal of Composites Science	Journal of Composites Science, 1, 10% Journal of Composites Science 1 publication, 10%
Journal of Applied Phycology	Journal of Applied Phycology, 1, 10% Journal of Applied Phycology 1 publication, 10%
International Journal of Nanomedicine	International Journal of Nanomedicine, 1, 10% International Journal of Nanomedicine 1 publication, 10%
Pharmaceutics	Pharmaceutics, 1, 10% Pharmaceutics 1 publication, 10%
ACS Applied Nano Materials	ACS Applied Nano Materials, 1, 10% ACS Applied Nano Materials 1 publication, 10%
Journal of Functional Biomaterials	Journal of Functional Biomaterials, 1, 10% Journal of Functional Biomaterials 1 publication, 10%
Journal of Physical Chemistry Letters	Journal of Physical Chemistry Letters, 1, 10% Journal of Physical Chemistry Letters 1 publication, 10%
Progress in Materials Science	Progress in Materials Science, 1, 10% Progress in Materials Science 1 publication, 10%
	1 2

Citations by publishers

	1 2 3 4 5
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 5, 50% Multidisciplinary Digital Publishing Institute (MDPI) 5 publications, 50%
American Chemical Society (ACS)	American Chemical Society (ACS), 2, 20% American Chemical Society (ACS) 2 publications, 20%
Springer Nature	Springer Nature, 1, 10% Springer Nature 1 publication, 10%
Dove Medical Press	Dove Medical Press, 1, 10% Dove Medical Press 1 publication, 10%
Elsevier	Elsevier, 1, 10% Elsevier 1 publication, 10%
	1 2 3 4 5

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Nikitin A. A. et al. Magneto-Mechanical Approach in Biomedicine: Benefits, Challenges, and Future Perspectives // International Journal of Molecular Sciences. 2022. Vol. 23. No. 19. p. 11134.

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Nikitin A. A., Ivanova A. V., Semkina A. S., Lazareva P. A., Abakumov M. A. Magneto-Mechanical Approach in Biomedicine: Benefits, Challenges, and Future Perspectives // International Journal of Molecular Sciences. 2022. Vol. 23. No. 19. p. 11134.

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RIS Copy

TY - JOUR

DO - 10.3390/ijms231911134

UR - https://doi.org/10.3390%2Fijms231911134

TI - Magneto-Mechanical Approach in Biomedicine: Benefits, Challenges, and Future Perspectives

T2 - International Journal of Molecular Sciences

AU - Ivanova, Anna V.

AU - Semkina, Alevtina S.

AU - Lazareva, Polina A

AU - Abakumov, Maxim A.

AU - Nikitin, Aleksey A

PY - 2022

DA - 2022/09/22 00:00:00

PB - Multidisciplinary Digital Publishing Institute (MDPI)

SP - 11134

IS - 19

VL - 23

PMID - 36232435

SN - 1661-6596

SN - 1422-0067

ER -

BibTex |

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BibTex Copy

@article{2022_Nikitin,

author = {Anna V. Ivanova and Alevtina S. Semkina and Polina A Lazareva and Maxim A. Abakumov and Aleksey A Nikitin},

title = {Magneto-Mechanical Approach in Biomedicine: Benefits, Challenges, and Future Perspectives},

journal = {International Journal of Molecular Sciences},

year = {2022},

volume = {23},

publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},

month = {sep},

url = {https://doi.org/10.3390%2Fijms231911134},

number = {19},

pages = {11134},

doi = {10.3390/ijms231911134}

}

MLA

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Nikitin, Aleksey A., et al. “Magneto-Mechanical Approach in Biomedicine: Benefits, Challenges, and Future Perspectives.” International Journal of Molecular Sciences, vol. 23, no. 19, Sep. 2022, p. 11134. https://doi.org/10.3390%2Fijms231911134.

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Publisher

Multidisciplinary Digital Publishing Institute (MDPI)

Journal

International Journal of Molecular Sciences

Quartile SCImago

Quartile WOS

Impact factor

5.6

ISSN

16616596 (Print)
14220067 (Electronic)

Labs

Biomedical Nanomaterials Laboratory

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