Open Access
Journal of Pharmacy and Bioallied Sciences, volume 3, issue 1, pages 4
Biomembrane models and drug-biomembrane interaction studies: Involvement in drug design and development
Publication type: Journal Article
Publication date: 2011-04-08
Quartile SCImago
Q2
Quartile WOS
—
Impact factor: 0.8
ISSN: 09764879, 09757406
PubMed ID:
21430952
General Biochemistry, Genetics and Molecular Biology
Bioengineering
General Pharmacology, Toxicology and Pharmaceutics
Abstract
Contact with many different biological membranes goes along the destiny of a drug after its systemic administration. From the circulating macrophage cells to the vessel endothelium, to more complex absorption barriers, the interaction of a biomolecule with these membranes largely affects its rate and time of biodistribution in the body and at the target sites. Therefore, investigating the phenomena occurring on the cell membranes, as well as their different interaction with drugs in the physiological or pathological conditions, is important to exploit the molecular basis of many diseases and to identify new potential therapeutic strategies. Of course, the complexity of the structure and functions of biological and cell membranes, has pushed researchers toward the proposition and validation of simpler two- and three-dimensional membrane models, whose utility and drawbacks will be discussed. This review also describes the analytical methods used to look at the interactions among bioactive compounds with biological membrane models, with a particular accent on the calorimetric techniques. These studies can be considered as a powerful tool for medicinal chemistry and pharmaceutical technology, in the steps of designing new drugs and optimizing the activity and safety profile of compounds already used in the therapy.
Citations by journals
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Chemistry and Physics of Lipids
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Chemistry and Physics of Lipids
5 publications, 5.15%
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International Journal of Pharmaceutics
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International Journal of Pharmaceutics
4 publications, 4.12%
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Colloids and Surfaces B: Biointerfaces
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Colloids and Surfaces B: Biointerfaces
3 publications, 3.09%
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Functional Materials
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Functional Materials, 3, 3.09%
Functional Materials
3 publications, 3.09%
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Pharmaceutics
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Pharmaceutics
2 publications, 2.06%
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Membranes
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Membranes
2 publications, 2.06%
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Journal of Solution Chemistry
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Journal of Solution Chemistry
2 publications, 2.06%
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Biochimica et Biophysica Acta - Biomembranes
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Biochimica et Biophysica Acta - Biomembranes
2 publications, 2.06%
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European Journal of Pharmaceutics and Biopharmaceutics
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European Journal of Pharmaceutics and Biopharmaceutics
2 publications, 2.06%
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Journal of Organometallic Chemistry
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Journal of Organometallic Chemistry
2 publications, 2.06%
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Chemical Physics Letters
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Chemical Physics Letters
2 publications, 2.06%
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Inorganic Chemistry
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Inorganic Chemistry
2 publications, 2.06%
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Langmuir
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Langmuir
2 publications, 2.06%
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RSC Advances
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RSC Advances
2 publications, 2.06%
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Biophysics (Russian Federation)
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Biophysics (Russian Federation)
2 publications, 2.06%
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Molecular Crystals and Liquid Crystals
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Molecular Crystals and Liquid Crystals
2 publications, 2.06%
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Materials Today Communications
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Materials Today Communications
1 publication, 1.03%
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Australian Journal of Chemistry
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Australian Journal of Chemistry
1 publication, 1.03%
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EPJ Web of Conferences
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EPJ Web of Conferences
1 publication, 1.03%
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Bioanalysis
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Bioanalysis
1 publication, 1.03%
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Fluids
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Fluids
1 publication, 1.03%
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Materials
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Materials
1 publication, 1.03%
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Molecules
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Molecules
1 publication, 1.03%
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Nanomaterials
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Nanomaterials
1 publication, 1.03%
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International Journal of Molecular Sciences
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International Journal of Molecular Sciences
1 publication, 1.03%
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Surfaces
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Surfaces
1 publication, 1.03%
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Biomimetics
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Biomimetics
1 publication, 1.03%
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Scientific Reports
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Scientific Reports
1 publication, 1.03%
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Leukemia
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Leukemia
1 publication, 1.03%
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5
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Citations by publishers
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5
10
15
20
25
30
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Elsevier
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Elsevier
29 publications, 29.9%
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
13 publications, 13.4%
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Springer Nature
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Springer Nature
9 publications, 9.28%
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American Chemical Society (ACS)
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American Chemical Society (ACS)
7 publications, 7.22%
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Taylor & Francis
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Taylor & Francis
6 publications, 6.19%
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Royal Society of Chemistry (RSC)
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Royal Society of Chemistry (RSC)
5 publications, 5.15%
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Wiley
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Wiley
4 publications, 4.12%
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National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka) (Publications)
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National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka) (Publications), 3, 3.09%
National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka) (Publications)
3 publications, 3.09%
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Pleiades Publishing
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Pleiades Publishing
2 publications, 2.06%
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Naukova Dumka
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Naukova Dumka, 2, 2.06%
Naukova Dumka
2 publications, 2.06%
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CSIRO Publishing
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CSIRO Publishing
1 publication, 1.03%
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EDP Sciences
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EDP Sciences
1 publication, 1.03%
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Future Medicine
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Future Medicine
1 publication, 1.03%
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Japan Oil Chemists' Society
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Japan Oil Chemists' Society
1 publication, 1.03%
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Beijing University of Chinese Medicine
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Beijing University of Chinese Medicine, 1, 1.03%
Beijing University of Chinese Medicine
1 publication, 1.03%
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, 1, 1.03%
1 publication, 1.03%
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Dove Medical Press
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Dove Medical Press
1 publication, 1.03%
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EManuscript Services
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EManuscript Services, 1, 1.03%
EManuscript Services
1 publication, 1.03%
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Oxford University Press
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Oxford University Press
1 publication, 1.03%
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American Institute of Mathematical Sciences (AIMS)
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American Institute of Mathematical Sciences (AIMS)
1 publication, 1.03%
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American Institute of Physics (AIP)
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American Institute of Physics (AIP)
1 publication, 1.03%
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Asian Journal of Chemistry
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Asian Journal of Chemistry
1 publication, 1.03%
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Korean Society for Biotechnology and Bioengineering
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Korean Society for Biotechnology and Bioengineering, 1, 1.03%
Korean Society for Biotechnology and Bioengineering
1 publication, 1.03%
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5
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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GOST
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Pignatello R. et al. Biomembrane models and drug-biomembrane interaction studies: Involvement in drug design and development // Journal of Pharmacy and Bioallied Sciences. 2011. Vol. 3. No. 1. p. 4.
GOST all authors (up to 50)
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Pignatello R., Musumeci T., Basile L., Carbone C., Puglisi G. Biomembrane models and drug-biomembrane interaction studies: Involvement in drug design and development // Journal of Pharmacy and Bioallied Sciences. 2011. Vol. 3. No. 1. p. 4.
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RIS
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TY - JOUR
DO - 10.4103/0975-7406.76461
UR - https://doi.org/10.4103%2F0975-7406.76461
TI - Biomembrane models and drug-biomembrane interaction studies: Involvement in drug design and development
T2 - Journal of Pharmacy and Bioallied Sciences
AU - Pignatello, R
AU - Musumeci, T
AU - Basile, L
AU - Carbone, C
AU - Puglisi, G
PY - 2011
DA - 2011/04/08 00:00:00
PB - Wolters Kluwer Health
SP - 4
IS - 1
VL - 3
PMID - 21430952
SN - 0976-4879
SN - 0975-7406
ER -
Cite this
BibTex
Copy
@article{2011,
author = {R Pignatello and T Musumeci and L Basile and C Carbone and G Puglisi},
title = {Biomembrane models and drug-biomembrane interaction studies: Involvement in drug design and development},
journal = {Journal of Pharmacy and Bioallied Sciences},
year = {2011},
volume = {3},
publisher = {Wolters Kluwer Health},
month = {apr},
url = {https://doi.org/10.4103%2F0975-7406.76461},
number = {1},
pages = {4},
doi = {10.4103/0975-7406.76461}
}