Journal of Biomaterials and Nanobiotechnology, volume 07, issue 02, pages 91-108
Effects of Size and Surface Charge of Polymeric Nanoparticles on in Vitro and in Vivo Applications
Publication type: Journal Article
Publication date: 2016-01-26
Quartile SCImago
— Quartile WOS
—
Impact factor: —
ISSN: 21587027, 21587043
Abstract
Biodegradable polymeric materials are the most common carriers for use in drug delivery systems. With this trend, newer drug delivery systems using targeted and controlled release polymeric nanoparticles (NPs) are being developed to manipulate their navigation in complex in vivo environment. However, a clear understanding of the interactions between biological systems and these nanoparticulates is still unexplored. Different studies have been performed to correlate the physicochemical properties of polymeric NPs with the biological responses. Size and surface charge are the two fundamental physicochemical properties that provide a key direction to design an effective NP formulation. In this critical review, our goal is to provide a brief overview on the influences of size and surface charge of different polymeric NPs in vitro and to highlight the challenges involved with in vivo trials.
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2 publications, 1.74%
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2 publications, 1.74%
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1 publication, 0.87%
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1 publication, 0.87%
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1 publication, 0.87%
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1 publication, 0.87%
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Citations by publishers
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36 publications, 31.3%
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Springer Nature
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13 publications, 11.3%
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Wiley
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11 publications, 9.57%
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American Chemical Society (ACS)
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7 publications, 6.09%
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5 publications, 4.35%
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2 publications, 1.74%
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1 publication, 0.87%
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1 publication, 0.87%
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Future Medicine
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Future Medicine
1 publication, 0.87%
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Portland Press
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Portland Press
1 publication, 0.87%
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1 publication, 0.87%
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Taylor & Francis
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1 publication, 0.87%
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1 publication, 0.87%
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Korean Association of Immunologists
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Korean Association of Immunologists, 1, 0.87%
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1 publication, 0.87%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Sadat S.M., Jahan S.T., Haddadi A. Effects of Size and Surface Charge of Polymeric Nanoparticles on in Vitro and in Vivo Applications // Journal of Biomaterials and Nanobiotechnology. 2016. Vol. 07. No. 02. pp. 91-108.
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Sadat S.M., Jahan S.T., Haddadi A. Effects of Size and Surface Charge of Polymeric Nanoparticles on in Vitro and in Vivo Applications // Journal of Biomaterials and Nanobiotechnology. 2016. Vol. 07. No. 02. pp. 91-108.
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TY - JOUR
DO - 10.4236/jbnb.2016.72011
UR - https://doi.org/10.4236%2Fjbnb.2016.72011
TI - Effects of Size and Surface Charge of Polymeric Nanoparticles on in Vitro and in Vivo Applications
T2 - Journal of Biomaterials and Nanobiotechnology
AU - Sadat, S M
AU - Jahan, S T
AU - Haddadi, A
PY - 2016
DA - 2016/01/26 00:00:00
PB - Scientific Research Publishing
SP - 91-108
IS - 02
VL - 07
SN - 2158-7027
SN - 2158-7043
ER -
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@article{2016,
author = {S M Sadat and S T Jahan and A Haddadi},
title = {Effects of Size and Surface Charge of Polymeric Nanoparticles on in Vitro and in Vivo Applications},
journal = {Journal of Biomaterials and Nanobiotechnology},
year = {2016},
volume = {07},
publisher = {Scientific Research Publishing},
month = {jan},
url = {https://doi.org/10.4236%2Fjbnb.2016.72011},
number = {02},
pages = {91--108},
doi = {10.4236/jbnb.2016.72011}
}