Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya, volume 63, issue 5, pages 4-11
SYNTHESIS AND STUDY OF SPECTRAL PROPERTIES OF AMINO ACIDS – BODIPY CONJUGATES
Publication type: Journal Article
Publication date: 2020-04-13
Quartile SCImago
Q3
Quartile WOS
—
Impact factor: 0.5
ISSN: 05792991, 25003070
General Chemistry
General Chemical Engineering
Abstract
The present work describes direct one-pot synthesis of the two novel amino acids – boron-dipyrromethene (BODIPY) conjugates with histidine and tyrosine residues bound to fluorophore via amino group. The synthesized compounds were fully characterized by means of 1H and 11B nuclear magnetic resonance spectroscopy, infrared spectroscopy, time-of-flight mass spectrometry with matrix-activated laser desorption / ionization. All the data are in accordance with the proposed structures. The amino acids – BODIPY conjugates under study were investigated by means of absorbance and fluorescence spectroscopy. Absorption and emission spectra of the compounds in dimethyl sulfoxide (DMSO) – buffer solution (BS) mixture (1:1) were obtained. Moreover, a number of photophysical characteristics of the conjugates, namely: relative fluorescence quantum yield, molar extinction coefficient, relative fluorescence lifetime, radiative and non-radiative rate constants were calulated. 3D fluorescence spectra of the compounds in DMSO – BS mixture (1:1) were obtained. Absorption and emission titration of the compounds was carried out. The results of the titration allowed us to confirm additionally a stoichiometric composition of the conjugates. Quantum chemical analysis of structural and spectral properties of the compounds in a ground state was carried out. The results of quantum chemical calculations gave an insight to a nature of the BODIPY – amino acid interactions in the conjugates. Besides, the synthesized amino acids – BODIPY conjugates are found to be highly soluble in polar solvents. Thus, a range of unique properties of the objects of the present research enables us to use them for visualization of bioactive macromolecules as well as biochemical processes in living cells.
Citations by journals
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Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya
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Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya
4 publications, 57.14%
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Journal of Molecular Liquids
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Journal of Molecular Liquids
1 publication, 14.29%
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Molecules
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Molecules
1 publication, 14.29%
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Russian Chemical Reviews
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Russian Chemical Reviews
1 publication, 14.29%
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Citations by publishers
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Ivanovo State University of Chemistry and Technology
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Ivanovo State University of Chemistry and Technology
4 publications, 57.14%
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Elsevier
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Elsevier
1 publication, 14.29%
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 14.29%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 14.29%
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- We do not take into account publications that without a DOI.
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- Statistics recalculated weekly.
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Ksenofontova K. V. N. et al. SYNTHESIS AND STUDY OF SPECTRAL PROPERTIES OF AMINO ACIDS – BODIPY CONJUGATES // Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya. 2020. Vol. 63. No. 5. pp. 4-11.
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Ksenofontova K. V. N., Ksenofontov A. A., Khodov I. A., Rumyantsev E. V. N. SYNTHESIS AND STUDY OF SPECTRAL PROPERTIES OF AMINO ACIDS – BODIPY CONJUGATES // Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya. 2020. Vol. 63. No. 5. pp. 4-11.
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TY - JOUR
DO - 10.6060/ivkkt.20206305.6101
UR - https://doi.org/10.6060%2Fivkkt.20206305.6101
TI - SYNTHESIS AND STUDY OF SPECTRAL PROPERTIES OF AMINO ACIDS – BODIPY CONJUGATES
T2 - Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya
AU - Ksenofontova, Ksenia V N
AU - Ksenofontov, Alexander A
AU - Khodov, Ilya A.
AU - Rumyantsev, Evgeniy V N
PY - 2020
DA - 2020/04/13 00:00:00
PB - Ivanovo State University of Chemistry and Technology
SP - 4-11
IS - 5
VL - 63
SN - 0579-2991
SN - 2500-3070
ER -
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@article{2020_Ksenofontova,
author = {Ksenia V N Ksenofontova and Alexander A Ksenofontov and Ilya A. Khodov and Evgeniy V N Rumyantsev},
title = {SYNTHESIS AND STUDY OF SPECTRAL PROPERTIES OF AMINO ACIDS – BODIPY CONJUGATES},
journal = {Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya},
year = {2020},
volume = {63},
publisher = {Ivanovo State University of Chemistry and Technology},
month = {apr},
url = {https://doi.org/10.6060%2Fivkkt.20206305.6101},
number = {5},
pages = {4--11},
doi = {10.6060/ivkkt.20206305.6101}
}
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Ksenofontova, Ksenia V. N., et al. “SYNTHESIS AND STUDY OF SPECTRAL PROPERTIES OF AMINO ACIDS – BODIPY CONJUGATES.” Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya, vol. 63, no. 5, Apr. 2020, pp. 4-11. https://doi.org/10.6060%2Fivkkt.20206305.6101.
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