Open Access
Biopolymers and Cell, volume 35, issue 3, pages 227-228
O-1. The role of the nuclear lamina in cell migration: The connection with aging and metastasis
Ovsiannikova N L
1, 2
,
Lavrushkina S V
1
,
Yudina A. S.
1
,
Strelkova O S
2
,
Zhironkina O A
2
,
Kireev I I
1, 2, 3
Publication type: Journal Article
Publication date: 2019-05-20
Journal:
Biopolymers and Cell
Quartile SCImago
Q4
Quartile WOS
—
Impact factor: —
ISSN: 02337657, 19936842
General Biochemistry, Genetics and Molecular Biology
Abstract
when H2B showed a H2A-like aggregated pattern in the nuclei� The cytoplasmic accumulation of H2B was confirmed also by mass spectrometric identification of elevated levels of H2B following Dox treatment in the dechromatinized samples� Conclusions: Anthra cyclines are widely used anti-cancer drugs exhibiting pleiotropic effects� At the chromatin level these include topoisomerase inhibition, DNA intercalation, aggregation of chromatin, histone eviction as well as direct binding to histones � The above large-scale effects were detected already at Dox concentrations that overlap serum peak levels reached in the typical clinical setting and therefore can be a factor both in the anticarcinogenic mechanism and in the side-effects of this anthracyclin�
Citations by journals
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1
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Biochemistry. Biokhimiia
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Biochemistry. Biokhimiia
1 publication, 50%
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Биохимия
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Биохимия
1 publication, 50%
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1
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Citations by publishers
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1
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Akademizdatcenter Nauka
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Akademizdatcenter Nauka
1 publication, 50%
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Pleiades Publishing
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Pleiades Publishing
1 publication, 50%
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1
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Ovsiannikova N. L. et al. O-1. The role of the nuclear lamina in cell migration: The connection with aging and metastasis // Biopolymers and Cell. 2019. Vol. 35. No. 3. pp. 227-228.
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Ovsiannikova N. L., Lavrushkina S. V., Yudina A. S., Strelkova O. S., Zhironkina O. A., Kireev I. I. O-1. The role of the nuclear lamina in cell migration: The connection with aging and metastasis // Biopolymers and Cell. 2019. Vol. 35. No. 3. pp. 227-228.
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TY - JOUR
DO - 10.7124/bc.0009F2
UR - https://doi.org/10.7124%2Fbc.0009F2
TI - O-1. The role of the nuclear lamina in cell migration: The connection with aging and metastasis
T2 - Biopolymers and Cell
AU - Ovsiannikova, N L
AU - Lavrushkina, S V
AU - Yudina, A. S.
AU - Strelkova, O S
AU - Zhironkina, O A
AU - Kireev, I I
PY - 2019
DA - 2019/05/20 00:00:00
PB - Naukova Dumka
SP - 227-228
IS - 3
VL - 35
SN - 0233-7657
SN - 1993-6842
ER -
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@article{2019_Ovsiannikova,
author = {N L Ovsiannikova and S V Lavrushkina and A. S. Yudina and O S Strelkova and O A Zhironkina and I I Kireev},
title = {O-1. The role of the nuclear lamina in cell migration: The connection with aging and metastasis},
journal = {Biopolymers and Cell},
year = {2019},
volume = {35},
publisher = {Naukova Dumka},
month = {may},
url = {https://doi.org/10.7124%2Fbc.0009F2},
number = {3},
pages = {227--228},
doi = {10.7124/bc.0009F2}
}
Cite this
MLA
Copy
Ovsiannikova, N. L., et al. “O-1. The role of the nuclear lamina in cell migration: The connection with aging and metastasis.” Biopolymers and Cell, vol. 35, no. 3, May. 2019, pp. 227-228. https://doi.org/10.7124%2Fbc.0009F2.