European Polymer Journal, volume 113, pages 67-77
Characterization of biomimetic silicate- and strontium-containing hydroxyapatite microparticles embedded in biodegradable electrospun polycaprolactone scaffolds for bone regeneration
Publication type: Journal Article
Publication date: 2019-04-01
Journal:
European Polymer Journal
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 6
ISSN: 00143057
Materials Chemistry
Organic Chemistry
General Physics and Astronomy
Polymers and Plastics
Abstract
Abstract A significant need exists today to develop novel alternatives to traditional bone grafts. Here, we report the potential use of mechanochemically synthesized hydroxyapatite (HA), silicate-, or strontium-containing HA microparticles and microparticle aggregates in combination with polycaprolactone (PCL) as hybrid scaffolds for filling bone defects. The detailed characterization of scaffolds was performed with high-resolution synchrotron radiation–based microcomputed laminography, XRD, EDX, and FTIR. An in vitro cell-scaffold interaction analysis showed a significant improvement of cell spreading in the case of hybrid scaffolds with silicate- and Sr-containing HA. Scaffolds with Sr- and silicate-containing HA affected the expression of several genes involved in morphogenesis and transcription. Scaffolds with Sr-containing HA increased the expression of markers of the primary component of the extracellular matrix, and scaffolds with Sr-containing HA facilitated cell mineralization via an increase in osteocalcin production. The hybrid scaffolds with silicate- and Sr-containing HA microparticles exerted the highest antibacterial activity against gram-positive bacterium Staphylococcus aureus compared to the unmodified PCL scaffolds. Based on these findings, the obtained scaffolds with Sr- or silicate-containing HA are believed to hold promise for bone tissue regeneration as compared to scaffolds containing pure HA.
Citations by journals
|
1
2
3
|
|
|
Polymers
|
Polymers
3 publications, 6.52%
|
|
European Polymer Journal
|
European Polymer Journal
3 publications, 6.52%
|
|
Journal of Materials Science
|
Journal of Materials Science
2 publications, 4.35%
|
|
Materials Today Communications
|
Materials Today Communications
2 publications, 4.35%
|
|
Bioprinting
|
Bioprinting
2 publications, 4.35%
|
|
Journal of Nanomaterials
|
Journal of Nanomaterials
1 publication, 2.17%
|
|
Journal of Thermoplastic Composite Materials
|
Journal of Thermoplastic Composite Materials
1 publication, 2.17%
|
|
Pharmaceutics
|
Pharmaceutics
1 publication, 2.17%
|
|
Biomedicines
|
Biomedicines
1 publication, 2.17%
|
|
Journal of Functional Biomaterials
|
Journal of Functional Biomaterials
1 publication, 2.17%
|
|
Frontiers in Chemistry
|
Frontiers in Chemistry
1 publication, 2.17%
|
|
Biomaterials Advances
|
Biomaterials Advances
1 publication, 2.17%
|
|
Materialia
|
Materialia
1 publication, 2.17%
|
|
Biomedical Materials (Bristol)
|
Biomedical Materials (Bristol)
1 publication, 2.17%
|
|
PLoS ONE
|
PLoS ONE
1 publication, 2.17%
|
|
Polymer Testing
|
Polymer Testing
1 publication, 2.17%
|
|
Composites Part B: Engineering
|
Composites Part B: Engineering
1 publication, 2.17%
|
|
Journal of the Mechanical Behavior of Biomedical Materials
|
Journal of the Mechanical Behavior of Biomedical Materials
1 publication, 2.17%
|
|
Journal of Alloys and Compounds
|
Journal of Alloys and Compounds
1 publication, 2.17%
|
|
Polymer Degradation and Stability
|
Polymer Degradation and Stability
1 publication, 2.17%
|
|
International Journal of Pharmaceutics
|
International Journal of Pharmaceutics
1 publication, 2.17%
|
|
Arabian Journal of Chemistry
|
Arabian Journal of Chemistry
1 publication, 2.17%
|
|
Journal of Orthopaedic Translation
|
Journal of Orthopaedic Translation
1 publication, 2.17%
|
|
Advanced Drug Delivery Reviews
|
Advanced Drug Delivery Reviews
1 publication, 2.17%
|
|
Biomaterials
|
Biomaterials
1 publication, 2.17%
|
|
Heliyon
|
Heliyon
1 publication, 2.17%
|
|
Journal of Materials Research and Technology
|
Journal of Materials Research and Technology
1 publication, 2.17%
|
|
Journal of Applied Polymer Science
|
Journal of Applied Polymer Science
1 publication, 2.17%
|
|
ACS Omega
|
ACS Omega
1 publication, 2.17%
|
|
Biomaterials Science
|
Biomaterials Science
1 publication, 2.17%
|
|
1
2
3
|
Citations by publishers
|
5
10
15
20
25
|
|
|
Elsevier
|
Elsevier
22 publications, 47.83%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
7 publications, 15.22%
|
|
Taylor & Francis
|
Taylor & Francis
3 publications, 6.52%
|
|
Hindawi Limited
|
Hindawi Limited
2 publications, 4.35%
|
|
Springer Nature
|
Springer Nature
2 publications, 4.35%
|
|
SAGE
|
SAGE
1 publication, 2.17%
|
|
Frontiers Media S.A.
|
Frontiers Media S.A.
1 publication, 2.17%
|
|
IOP Publishing
|
IOP Publishing
1 publication, 2.17%
|
|
Public Library of Science (PLoS)
|
Public Library of Science (PLoS)
1 publication, 2.17%
|
|
King Saud University
|
King Saud University
1 publication, 2.17%
|
|
Wiley
|
Wiley
1 publication, 2.17%
|
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
1 publication, 2.17%
|
|
Royal Society of Chemistry (RSC)
|
Royal Society of Chemistry (RSC)
1 publication, 2.17%
|
|
Dove Medical Press
|
Dove Medical Press
1 publication, 2.17%
|
|
5
10
15
20
25
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0],"codes":[0,0,0,0,0,0],"imageUrls":["","","","","",""],"datasets":[{"label":"Citations number","data":[7,8,11,10,8,2],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["15.22","17.39","23.91","21.74","17.39","4.35"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Polymers","European Polymer Journal","Journal of Materials Science","Materials Today Communications","Bioprinting","Journal of Nanomaterials","Journal of Thermoplastic Composite Materials","Pharmaceutics","Biomedicines","Journal of Functional Biomaterials","Frontiers in Chemistry","Biomaterials Advances","Materialia","Biomedical Materials (Bristol)","PLoS ONE","Polymer Testing","Composites Part B: Engineering","Journal of the Mechanical Behavior of Biomedical Materials","Journal of Alloys and Compounds","Polymer Degradation and Stability","International Journal of Pharmaceutics","Arabian Journal of Chemistry","Journal of Orthopaedic Translation","Advanced Drug Delivery Reviews","Biomaterials","Heliyon","Journal of Materials Research and Technology","Journal of Applied Polymer Science","ACS Omega","Biomaterials Science"],"ids":[11204,17319,11453,12228,10176,20485,21377,4502,24421,19043,6407,27992,11140,13063,24963,25045,10468,16202,4015,10686,3305,18459,14706,12266,13732,21848,18488,513,18901,12476],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/9z7b0TQJNgUxZHYXLrTmbnjJn9y5iq56Wxtqb1Lv_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp"],"datasets":[{"label":"","data":[3,3,2,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[6.52,6.52,4.35,4.35,4.35,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","Taylor & Francis","Hindawi Limited","Springer Nature","SAGE","Frontiers Media S.A.","IOP Publishing","Public Library of Science (PLoS)","King Saud University","Wiley","American Chemical Society (ACS)","Royal Society of Chemistry (RSC)","Dove Medical Press"],"ids":[17,202,18,6921,8,31,208,2075,344,171,11,40,123,417],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/9z7b0TQJNgUxZHYXLrTmbnjJn9y5iq56Wxtqb1Lv_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/wVWp6zaxUsMdR03dYMdOZoesUrVGtNMWkHKByIvT_medium.webp"],"datasets":[{"label":"","data":[22,7,3,2,2,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[47.83,15.22,6.52,4.35,4.35,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17,2.17],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Shkarina S. et al. Characterization of biomimetic silicate- and strontium-containing hydroxyapatite microparticles embedded in biodegradable electrospun polycaprolactone scaffolds for bone regeneration // European Polymer Journal. 2019. Vol. 113. pp. 67-77.
GOST all authors (up to 50)
Copy
Shkarina S., Syromotina D. S., Melnik E. V., Shkarin R., Selezneva I. I., Ivlev S. I., Cecilia A., Weinhardt V., Baumbach T., Rijavec T., Lapanje A., Chaikina M. V., Surmeneva M. A., Surmenev R. A., Ermakov A. M. Characterization of biomimetic silicate- and strontium-containing hydroxyapatite microparticles embedded in biodegradable electrospun polycaprolactone scaffolds for bone regeneration // European Polymer Journal. 2019. Vol. 113. pp. 67-77.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.eurpolymj.2019.01.042
UR - https://doi.org/10.1016%2Fj.eurpolymj.2019.01.042
TI - Characterization of biomimetic silicate- and strontium-containing hydroxyapatite microparticles embedded in biodegradable electrospun polycaprolactone scaffolds for bone regeneration
T2 - European Polymer Journal
AU - Shkarina, Svetlana
AU - Syromotina, Dina S
AU - Melnik, Elizaveta V
AU - Shkarin, Roman
AU - Selezneva, Irina I.
AU - Ivlev, Sergei I.
AU - Cecilia, Angelica
AU - Weinhardt, Venera
AU - Baumbach, Tilo
AU - Rijavec, Tomaž
AU - Lapanje, Ales
AU - Chaikina, Marina V.
AU - Surmeneva, Maria A
AU - Surmenev, Roman A
AU - Ermakov, Artem M
PY - 2019
DA - 2019/04/01 00:00:00
PB - Elsevier
SP - 67-77
VL - 113
SN - 0014-3057
ER -
Cite this
BibTex
Copy
@article{2019_Shkarina,
author = {Svetlana Shkarina and Dina S Syromotina and Elizaveta V Melnik and Roman Shkarin and Irina I. Selezneva and Sergei I. Ivlev and Angelica Cecilia and Venera Weinhardt and Tilo Baumbach and Tomaž Rijavec and Ales Lapanje and Marina V. Chaikina and Maria A Surmeneva and Roman A Surmenev and Artem M Ermakov},
title = {Characterization of biomimetic silicate- and strontium-containing hydroxyapatite microparticles embedded in biodegradable electrospun polycaprolactone scaffolds for bone regeneration},
journal = {European Polymer Journal},
year = {2019},
volume = {113},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016%2Fj.eurpolymj.2019.01.042},
pages = {67--77},
doi = {10.1016/j.eurpolymj.2019.01.042}
}
Profiles