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Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step

Auhim H.S., Grigorenko B.L., Harris T.K., Aksakal O.E., Polyakov I.V., Berry C., Gomes G.D., Alabugin I.V., Rizkallah P.J., Nemukhin A.V., Jones D.D.
Тип документаJournal Article
Дата публикации2021-06-14
Название журналаChemical Science
ИздательThe Royal Society of Chemistry
КвартильQ1
ISSN20416520, 20416539
  • General Chemistry
Краткое описание

Fluorescent proteins (FPs) have revolutionised the life sciences, but the chromophore maturation mechanism is still not fully understood. Here we photochemically trap maturation at a crucial stage and structurally characterise the intermediate.

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1. Auhim H.S. и др. Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step // Chemical Science. 2021. Т. 12. № 22. С. 7735–7745.
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TY - JOUR

DO - 10.1039/d0sc06693a

UR - http://dx.doi.org/10.1039/d0sc06693a

TI - Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step

T2 - Chemical Science

AU - Auhim, Husam Sabah

AU - Grigorenko, Bella L.

AU - Harris, Tessa K.

AU - Aksakal, Ozan E.

AU - Polyakov, Igor V.

AU - Berry, Colin

AU - Gomes, Gabriel dos Passos

AU - Alabugin, Igor V.

AU - Rizkallah, Pierre J.

AU - Nemukhin, Alexander V.

AU - Jones, D. Dafydd

PY - 2021

PB - Royal Society of Chemistry (RSC)

SP - 7735-7745

IS - 22

VL - 12

SN - 2041-6520

SN - 2041-6539

ER -

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@article{2021,

doi = {10.1039/d0sc06693a},

url = {https://doi.org/10.1039%2Fd0sc06693a},

year = 2021,

publisher = {Royal Society of Chemistry ({RSC})},

volume = {12},

number = {22},

pages = {7735--7745},

author = {Husam Sabah Auhim and Bella L. Grigorenko and Tessa K. Harris and Ozan E. Aksakal and Igor V. Polyakov and Colin Berry and Gabriel dos Passos Gomes and Igor V. Alabugin and Pierre J. Rizkallah and Alexander V. Nemukhin and D. Dafydd Jones},

title = {Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step}

}

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Auhim, Husam Sabah et al. “Stalling Chromophore Synthesis of the Fluorescent Protein Venus Reveals the Molecular Basis of the Final Oxidation Step.” Chemical Science 12.22 (2021): 7735–7745. Crossref. Web.