Tetrahedron Letters, volume 61, issue 11, pages 151595

Facile approach to alkaloid-like 6/6/5/5-tetracyclic spiroheterocycles via 1,3-dipolar cycloaddition reaction of fused 1H-pyrrole-2,3-diones with nitrones

Publication typeJournal Article
Publication date2020-03-01
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor1.8
ISSN00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Abstract A facile synthetic approach towards 6/6/5/5-tetracyclic spiroheterocycles has been developed from the highly diastereoselective 1,3-dipolar cycloaddition reaction of [e]-fused 1H-pyrrole-2,3-diones with nitrones. The described novel heterocyclic systems are heteroanalogs of cytotoxic alkaloids, kibalaurifoline and gitingensine. The developed reaction represents the first example of involvement of 1H-pyrrole-2,3-diones fused at [e]-side in a 1,3-dipolar cycloaddition reaction.

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Khramtsova E. E. et al. Facile approach to alkaloid-like 6/6/5/5-tetracyclic spiroheterocycles via 1,3-dipolar cycloaddition reaction of fused 1H-pyrrole-2,3-diones with nitrones // Tetrahedron Letters. 2020. Vol. 61. No. 11. p. 151595.
GOST all authors (up to 50) Copy
Khramtsova E. E., Dmitriev M. V., Maslivets A. N., Dmitriev M. V., Maslivets A. N. Facile approach to alkaloid-like 6/6/5/5-tetracyclic spiroheterocycles via 1,3-dipolar cycloaddition reaction of fused 1H-pyrrole-2,3-diones with nitrones // Tetrahedron Letters. 2020. Vol. 61. No. 11. p. 151595.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.tetlet.2020.151595
UR - https://doi.org/10.1016%2Fj.tetlet.2020.151595
TI - Facile approach to alkaloid-like 6/6/5/5-tetracyclic spiroheterocycles via 1,3-dipolar cycloaddition reaction of fused 1H-pyrrole-2,3-diones with nitrones
T2 - Tetrahedron Letters
AU - Khramtsova, Ekaterina E
AU - Dmitriev, Maksim V.
AU - Maslivets, Andrey N.
AU - Dmitriev, Maksim V
AU - Maslivets, Andrey N
PY - 2020
DA - 2020/03/01 00:00:00
PB - Elsevier
SP - 151595
IS - 11
VL - 61
SN - 0040-4039
SN - 1873-3581
ER -
BibTex |
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BibTex Copy
@article{2020_Khramtsova
author = {Ekaterina E Khramtsova and Maksim V. Dmitriev and Andrey N. Maslivets and Maksim V Dmitriev and Andrey N Maslivets},
title = {Facile approach to alkaloid-like 6/6/5/5-tetracyclic spiroheterocycles via 1,3-dipolar cycloaddition reaction of fused 1H-pyrrole-2,3-diones with nitrones},
journal = {Tetrahedron Letters},
year = {2020},
volume = {61},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016%2Fj.tetlet.2020.151595},
number = {11},
pages = {151595},
doi = {10.1016/j.tetlet.2020.151595}
}
MLA
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MLA Copy
Khramtsova, Ekaterina E., et al. “Facile approach to alkaloid-like 6/6/5/5-tetracyclic spiroheterocycles via 1,3-dipolar cycloaddition reaction of fused 1H-pyrrole-2,3-diones with nitrones.” Tetrahedron Letters, vol. 61, no. 11, Mar. 2020, p. 151595. https://doi.org/10.1016%2Fj.tetlet.2020.151595.
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