Open Access
Nucleic Acids Research, volume 47, issue 13, pages 6858-6870
Coding palindromes in mitochondrial genes of Nematomorpha
Михайлов К. В.
1, 2
,
Efeykin Boris D.
1, 3
,
Panchin Alexander Y.
1
,
Кнорре Д. А.
2, 4
,
Logacheva Maria D.
1, 2, 5
,
Penin Aleksey A
1, 2
,
Muntyan M. S.
2
,
Никитин М. А.
1, 2
,
Popova Olga V
2
,
Zanegina Olga N
2
,
Vyssokikh M. Yu.
2
,
Aleoshin Vladimir V.
1, 2
,
Panchin Yu. V.
1, 2
Publication type: Journal Article
Publication date: 2019-06-13
Journal:
Nucleic Acids Research
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 14.9
ISSN: 03051048, 13624962
PubMed ID:
31194871
Genetics
Abstract
Inverted repeats are common DNA elements, but they rarely overlap with protein-coding sequences due to the ensuing conflict with the structure and function of the encoded protein. We discovered numerous perfect inverted repeats of considerable length (up to 284 bp) embedded within the protein-coding genes in mitochondrial genomes of four Nematomorpha species. Strikingly, both arms of the inverted repeats encode conserved regions of the amino acid sequence. We confirmed enzymatic activity of the respiratory complex I encoded by inverted repeat-containing genes. The nucleotide composition of inverted repeats suggests strong selection at the amino acid level in these regions. We conclude that the inverted repeat-containing genes are transcribed and translated into functional proteins. The survey of available mitochondrial genomes reveals that several other organisms possess similar albeit shorter embedded repeats. Mitochondrial genomes of Nematomorpha demonstrate an extraordinary evolutionary compromise where protein function and stringent secondary structure elements within the coding regions are preserved simultaneously.
Citations by journals
|
1
|
|
|
Genes
|
Genes
1 publication, 12.5%
|
|
Biosensors and Bioelectronics
|
Biosensors and Bioelectronics
1 publication, 12.5%
|
|
BMC Biology
|
BMC Biology
1 publication, 12.5%
|
|
Nucleic Acids Research
|
Nucleic Acids Research
1 publication, 12.5%
|
|
International Journal of Molecular Sciences
|
International Journal of Molecular Sciences
1 publication, 12.5%
|
|
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution
|
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution
1 publication, 12.5%
|
|
1
|
Citations by publishers
|
1
2
|
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
2 publications, 25%
|
|
Elsevier
|
Elsevier
1 publication, 12.5%
|
|
Springer Nature
|
Springer Nature
1 publication, 12.5%
|
|
Oxford University Press
|
Oxford University Press
1 publication, 12.5%
|
|
Wiley
|
Wiley
1 publication, 12.5%
|
|
1
2
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0],"codes":[0,0,0,0,0,0],"imageUrls":["","","","","",""],"datasets":[{"label":"Citations number","data":[2,0,2,0,3,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["25",0,"25",0,"37.5","12.5"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Genes","Biosensors and Bioelectronics","BMC Biology","Nucleic Acids Research","International Journal of Molecular Sciences","Journal of Experimental Zoology Part B: Molecular and Developmental Evolution"],"ids":[8879,18799,8160,23904,14627,881],"codes":[0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp"],"datasets":[{"label":"","data":[1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[12.5,12.5,12.5,12.5,12.5,12.5],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Multidisciplinary Digital Publishing Institute (MDPI)","Elsevier","Springer Nature","Oxford University Press","Wiley"],"ids":[202,17,8,19,11],"codes":[0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp"],"datasets":[{"label":"","data":[2,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[25,12.5,12.5,12.5,12.5],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Михайлов К. В. et al. Coding palindromes in mitochondrial genes of Nematomorpha // Nucleic Acids Research. 2019. Vol. 47. No. 13. pp. 6858-6870.
GOST all authors (up to 50)
Copy
Михайлов К. В., Efeykin B. D., Panchin A. Y., Кнорре Д. А., Logacheva M. D., Penin A. A., Muntyan M. S., Никитин М. А., Popova O. V., Zanegina O. N., Vyssokikh M. Y., SPIRIDONOV S. E., Aleoshin V. V., Panchin Y. V. Coding palindromes in mitochondrial genes of Nematomorpha // Nucleic Acids Research. 2019. Vol. 47. No. 13. pp. 6858-6870.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1093/nar/gkz517
UR - https://doi.org/10.1093%2Fnar%2Fgkz517
TI - Coding palindromes in mitochondrial genes of Nematomorpha
T2 - Nucleic Acids Research
AU - Михайлов, К. В.
AU - Popova, Olga V
AU - Zanegina, Olga N
AU - Logacheva, Maria D.
AU - Efeykin, Boris D.
AU - Panchin, Alexander Y.
AU - Кнорре, Д. А.
AU - Penin, Aleksey A
AU - Muntyan, M. S.
AU - Никитин, М. А.
AU - Vyssokikh, M. Yu.
AU - SPIRIDONOV, SERGEI E.
AU - Aleoshin, Vladimir V.
AU - Panchin, Yu. V.
PY - 2019
DA - 2019/06/13 00:00:00
PB - Oxford University Press
SP - 6858-6870
IS - 13
VL - 47
PMID - 31194871
SN - 0305-1048
SN - 1362-4962
ER -
Cite this
BibTex
Copy
@article{2019_Михайлов,
author = {К. В. Михайлов and Olga V Popova and Olga N Zanegina and Maria D. Logacheva and Boris D. Efeykin and Alexander Y. Panchin and Д. А. Кнорре and Aleksey A Penin and M. S. Muntyan and М. А. Никитин and M. Yu. Vyssokikh and SERGEI E. SPIRIDONOV and Vladimir V. Aleoshin and Yu. V. Panchin},
title = {Coding palindromes in mitochondrial genes of Nematomorpha},
journal = {Nucleic Acids Research},
year = {2019},
volume = {47},
publisher = {Oxford University Press},
month = {jun},
url = {https://doi.org/10.1093%2Fnar%2Fgkz517},
number = {13},
pages = {6858--6870},
doi = {10.1093/nar/gkz517}
}
Cite this
MLA
Copy
Михайлов, К. В., et al. “Coding palindromes in mitochondrial genes of Nematomorpha.” Nucleic Acids Research, vol. 47, no. 13, Jun. 2019, pp. 6858-6870. https://doi.org/10.1093%2Fnar%2Fgkz517.
Profiles