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Biomedical Optics Express, volume 9, issue 3, pages 1198

Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods

Smolyanskaya O. A. 1
Schelkanova I J 1
Kulya M S 1
Odlyanitskiy E L 1
Goryachev I S 1
Tcypkin A N 1
Grachev Ya V 1
Toropova Ya G 2
Tuchin V. V. 1
Publication typeJournal Article
Publication date2018-02-16
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor3.4
ISSN21567085
PubMed ID:  29541513
Biotechnology
Atomic and Molecular Physics, and Optics
Abstract
The optical clearing method has been widely used for different spectral ranges where it provides tissue transparency. In this work, we observed the enhanced penetration of the terahertz waves inside biological samples (skin, kidney, and cornea) treated with glycerol solutions inducing changes of optical and dielectric properties. It was supported by the observed trend of free-to-bound water ratio measured by the nuclear magnetic resonance (NMR) method. The terahertz clearing efficiency was found to be less for diabetic samples than for normal ones. Results of the numerical simulation proved that pulse deformation is due to bigger penetration depth caused by the reduction of absorption and refraction at optical clearing.

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Smolyanskaya O. A. et al. Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods // Biomedical Optics Express. 2018. Vol. 9. No. 3. p. 1198.
GOST all authors (up to 50) Copy
Smolyanskaya O. A., Schelkanova I. J., Kulya M. S., Odlyanitskiy E. L., Goryachev I. S., Tcypkin A. N., Grachev Ya. V., Toropova Ya. G., Tuchin V. V. Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods // Biomedical Optics Express. 2018. Vol. 9. No. 3. p. 1198.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1364/BOE.9.001198
UR - https://doi.org/10.1364%2FBOE.9.001198
TI - Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods
T2 - Biomedical Optics Express
AU - Smolyanskaya, O. A.
AU - Schelkanova, I J
AU - Odlyanitskiy, E L
AU - Goryachev, I S
AU - Grachev, Ya V
AU - Toropova, Ya G
AU - Tcypkin, A N
AU - Kulya, M S
AU - Tuchin, V. V.
PY - 2018
DA - 2018/02/16 00:00:00
PB - Optical Society of America
SP - 1198
IS - 3
VL - 9
PMID - 29541513
SN - 2156-7085
ER -
BibTex |
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BibTex Copy
@article{2018_Smolyanskaya,
author = {O. A. Smolyanskaya and I J Schelkanova and E L Odlyanitskiy and I S Goryachev and Ya V Grachev and Ya G Toropova and A N Tcypkin and M S Kulya and V. V. Tuchin},
title = {Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods},
journal = {Biomedical Optics Express},
year = {2018},
volume = {9},
publisher = {Optical Society of America},
month = {feb},
url = {https://doi.org/10.1364%2FBOE.9.001198},
number = {3},
pages = {1198},
doi = {10.1364/BOE.9.001198}
}
MLA
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Smolyanskaya, O. A., et al. “Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods.” Biomedical Optics Express, vol. 9, no. 3, Feb. 2018, p. 1198. https://doi.org/10.1364%2FBOE.9.001198.
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