Journal of Analytical Chemistry, volume 76, issue 11, pages 1312-1320
A New Derivatizing Agent for Determining Nitrofuran Metabolites in Chicken Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Melekhin A O
1, 2
,
Tolmacheva V.V.
1
,
Shubina E G
2
,
Dmitrienko S G
1
,
Apyari V V
1
,
Grudev A I
2
,
2
Central Research and Methodological Veterinary Laboratory, Moscow, Russia
|
Publication type: Journal Article
Publication date: 2021-11-14
Journal:
Journal of Analytical Chemistry
Quartile SCImago
Q4
Quartile WOS
Q4
Impact factor: 1.1
ISSN: 10619348, 16083199
Analytical Chemistry
Abstract
5-Nitro-2-furaldehyde is proposed as a new derivatizing agent for determining four nitrofuran metabolites: 3-amino-2-oxazolidinone, 3-amino-5-methylmorpholino-2-oxazolidinone, 1-aminohydantoin, and semicarbazide in chicken eggs by HPLC with tandem mass spectrometric detection. The derivatization products were identified; they are the initial nitrofurans: furazolidone, furaltadone, nitrofurantoin, and nitrofurazone, respectively. Sample preparation includes acid hydrolysis, derivatization, fat removal by hexane extraction, and the further purification of the extracts on cartridges packed with Diapak P-3 hypercrosslinked polystyrene. The method ensures the quantitative isolation of metabolites (recovery rates are 95 to 106%) and good reproducibility (RSD ≤ 13%).
Citations by journals
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1
2
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Journal of Analytical Chemistry
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Journal of Analytical Chemistry
2 publications, 40%
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Journal of Chromatography A
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Journal of Chromatography A
1 publication, 20%
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Ecotoxicology and Environmental Safety
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Ecotoxicology and Environmental Safety
1 publication, 20%
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ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT
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ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, 1, 20%
ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT
1 publication, 20%
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1
2
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Citations by publishers
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1
2
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Elsevier
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Elsevier
2 publications, 40%
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Pleiades Publishing
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Pleiades Publishing
2 publications, 40%
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Federal Center for Hygiene and Epidemiology
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Federal Center for Hygiene and Epidemiology, 1, 20%
Federal Center for Hygiene and Epidemiology
1 publication, 20%
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1
2
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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GOST
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Melekhin A. O. et al. A New Derivatizing Agent for Determining Nitrofuran Metabolites in Chicken Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry // Journal of Analytical Chemistry. 2021. Vol. 76. No. 11. pp. 1312-1320.
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Melekhin A. O., Tolmacheva V., Shubina E. G., Dmitrienko S. G., Apyari V. V., Grudev A. I., Zolotov Y. A New Derivatizing Agent for Determining Nitrofuran Metabolites in Chicken Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry // Journal of Analytical Chemistry. 2021. Vol. 76. No. 11. pp. 1312-1320.
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TY - JOUR
DO - 10.1134/S1061934821110071
UR - https://doi.org/10.1134%2FS1061934821110071
TI - A New Derivatizing Agent for Determining Nitrofuran Metabolites in Chicken Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry
T2 - Journal of Analytical Chemistry
AU - Melekhin, A O
AU - Tolmacheva, V.V.
AU - Dmitrienko, S G
AU - Grudev, A I
AU - Zolotov, Yu.A
AU - Shubina, E G
AU - Apyari, V V
PY - 2021
DA - 2021/11/14 00:00:00
PB - Pleiades Publishing
SP - 1312-1320
IS - 11
VL - 76
SN - 1061-9348
SN - 1608-3199
ER -
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@article{2021_Melekhin,
author = {A O Melekhin and V.V. Tolmacheva and S G Dmitrienko and A I Grudev and Yu.A Zolotov and E G Shubina and V V Apyari},
title = {A New Derivatizing Agent for Determining Nitrofuran Metabolites in Chicken Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry},
journal = {Journal of Analytical Chemistry},
year = {2021},
volume = {76},
publisher = {Pleiades Publishing},
month = {nov},
url = {https://doi.org/10.1134%2FS1061934821110071},
number = {11},
pages = {1312--1320},
doi = {10.1134/S1061934821110071}
}
Cite this
MLA
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Melekhin, A. O., et al. “A New Derivatizing Agent for Determining Nitrofuran Metabolites in Chicken Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry.” Journal of Analytical Chemistry, vol. 76, no. 11, Nov. 2021, pp. 1312-1320. https://doi.org/10.1134%2FS1061934821110071.